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Research article   Open Access

Impact of hepatitis C virus co-infection on HIV patients before and after highly active antiretroviral therapy: an immunological and clinical chemistry observation, Addis Ababa, Ethiopia

Solomon Taye, Mekuria Lakew BMC Immunology 2013, 14:23 (17 May 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

Expression of Toll-like Receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum

Maria M Figueiredo, Izabela FG Amorim, Aldair JW Pinto, Vítor S Barbosa, Lucélia de Jesus Pinheiro, Beatriz Deoti, Ana MC Faria, Wagner L Tafuri BMC Immunology 2013, 14:22 (14 May 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese Chinese

Yun-Ping Lim, Yu-An Hsu, Kun-Hsi Tsai, Fuu-Jen Tsai, Cheng-Yuan Peng, Wen-Ling Liao, Dong-Zong Hung, Ni Tien, Chien-Yih Lin, Lei Wan BMC Immunology 2013, 14:21 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

Inhibitory effect of IL-17 on neural stem cell proliferation and neural cell differentiation

Zichen Li, Ke Li, Lin Zhu, Quancheng Kan, Yaping Yan, Priyanka Kumar, Hui Xu, Abdolmohamad Rostami, Guang-Xian Zhang BMC Immunology 2013, 14:20 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

The distribution of IgG subclass deposition on renal tissues from patients with anti-glomerular basement membrane disease

Zhen Qu, Zhao Cui, Gang Liu, Ming-hui Zhao BMC Immunology 2013, 14:19 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Reviewer acknowledgement   Open Access

Annual acknowledgement of manuscript reviewers

Christopher Morrey BMC Immunology 2013, 14:13 (10 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

Expression profiling of lymph node cells from deer mice infected with Andes virus

Tony Schountz, Timothy I Shaw, Travis C Glenn, Heinz Feldmann, Joseph Prescott BMC Immunology 2013, 14:18 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Novel methodology for designing real-time PCR arrays in deer mice indicates that lymph node T cells from those infected with ANDV express mostly genes of the Th2 phenotype but fewer genes of Th1 and Treg phenotypes.

Research article   Open Access

Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock

Rafael Bojalil, María Teresa Mata-González, Fausto Sánchez-Muñoz, Yepci Yee, Iván Argueta, Lucía Bolaños, Luis Manuel Amezcua-Guerra, Tanya Amanda Camacho-Villegas, Edna Sánchez-Castrejón, Walter Jakob García-Ubbelohde, Alexei Fedorovish Licea-Navarro, Ricardo Márquez-Velasco, Jorge Fernando Paniagua-Solís BMC Immunology 2013, 14:17 (2 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

BATF regulates the development and function of IL-17 producing iNKT cells

Kimberly L Jordan-Williams, Stacie Poston, Elizabeth J Taparowsky BMC Immunology 2013, 14:16 (27 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

Winnie A Okeyo, Elly O Munde, Wilson Okumu, Evans Raballah, Samuel B Anyona, John M Vulule, John M Ong’echa, Douglas J Perkins, Collins Ouma BMC Immunology 2013, 14:15 (25 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Characterisation of CD154+ T cells following ex vivo birch allergen stimulation defines a close relationship between T cell subsets in healthy volunteers

Karen A Smith, Nicola J Gray, Elizabeth Cheek, Femi Saleh, Jo Lavender, Anthony J Frew, Florian Kern, Michael D Tarzi BMC Immunology 2013, 14:14 (22 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

CD154+ T cell responses to birch allergen in an ex vivo stimulation system suggest a close relationship between Th1, Th2 and Tr1-like responses to birch allergen that maintain a low Th2:Th1 ratio.

Research article   Open Access

CpG oligonucleotides bind TLR9 and RRM-Containing proteins in Atlantic Salmon (Salmo salar)

Dimitar B Iliev, Ingrid Skjæveland, Jorunn B Jørgensen BMC Immunology 2013, 14:12 (1 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Blomia tropicalis Blo t 5 and Blo t 21 recombinant allergens might confer higher specificity to serodiagnostic assays than whole mite extract

Kellyanne dos Anjos Carvalho, Osvaldo Pompílio de Melo-Neto, Franklin Barbalho Magalhães, João Carlos Marques Ponte, Filipe Adriano Borba Felipe, Mariese Conceição Alves dos Santos, Givaneide dos Santos Lima, Álvaro Augusto Cruz, Carina Silva Pinheiro, Lain Carlos Pontes-de-Carvalho, Neuza Maria Alcantara-Neves BMC Immunology 2013, 14:11 (27 February 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin

Peggy Bodammer, Elisabeth Zirzow, Sebastian Klammt, Claudia Maletzki, Claus Kerkhoff BMC Immunology 2013, 14:10 (20 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Serum biomarker analysis of collagen disease patients with acute-onset diffuse interstitial lung disease

Shomi Oka, Hiroshi Furukawa, Kota Shimada, Hiromi Hayakawa, Naoshi Fukui, Naoyuki Tsuchiya, Shigeto Tohma BMC Immunology 2013, 14:9 (14 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Serum biomarker profiling in collagen disease patients supports MMP-3 to MMP-1 ratio, and levels of TIMP-3, MMP-9, and osteopontin as prognosis markers for acute-onset diffuse interstitial lung disease. 

Research article   Open Access Highly Accessed

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study

Axel Nierhaus, Stefanie Klatte, Jo Linssen, Nina M Eismann, Dominic Wichmann, Jörg Hedke, Stephan A Braune, Stefan Kluge BMC Immunology 2013, 14:8 (12 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Immature granulocyte (IG) count in peripheral blood is an effective marker for identifying infected patients during the early onset of systemic inflammatory response syndrome (SIRS), suggesting routine measurement could offer new potential for rapid screening.

Research article   Open Access Highly Accessed

Budesonide suppresses pulmonary antibacterial host defense by down-regulating cathelicidin-related antimicrobial peptide in allergic inflammation mice and in lung epithelial cells

Peng Wang, Xiaoyun Wang, Xiaoqiong Yang, Zhigang Liu, Min Wu, Guoping Li BMC Immunology 2013, 14:7 (6 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The suppression of pulmonary antibacterial host defense by budesonide in an asthmatic mouse model and in lung epithelium cells in vitro is dependent on down-regulation of cathelicidin-related antimicrobial peptide. 

Research article   Open Access Highly Accessed

Characterization of murine macrophages from bone marrow, spleen and peritoneum

Changqi Wang, Xiao Yu, Qi Cao, Ya Wang, Guoping Zheng, Thian Kui Tan, Hong Zhao, Ye Zhao, Yiping Wang, David CH Harris BMC Immunology 2013, 14:6 (5 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A comparison study of mouse macrophages derived from spleen, bone marrow and peritoneum demonstrates their distinct characteristics which may be relevant to their respective roles in the immune response.

Research article   Open Access Highly Accessed

Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors

Kimberly Gwin, Joseph J Dolence, Mariya B Shapiro, Kay L Medina BMC Immunology 2013, 14:5 (30 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Effects of HIV-1-induced CD1c and CD1d modulation and endogenous lipid presentation on CD1c-restricted T-cell activation

Halonna Kelly, Rajakumar Mandraju, Jordana GA Coelho-dos-Reis, Moriya Tsuji BMC Immunology 2013, 14:4 (24 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Human CD3γ, but not CD3δ, haploinsufficiency differentially impairs γδ versus αβ surface TCR expression

Miguel Muñoz-Ruiz, Verónica Pérez-Flores, Beatriz Garcillán, Alberto C Guardo, Marina S Mazariegos, Hidetoshi Takada, Luis M Allende, Sara S Kilic, Ozden Sanal, Chaim M Roifman, Eduardo López-Granados, María J Recio, Eduardo Martínez-Naves, Edgar Fernández-Malavé, José R Regueiro BMC Immunology 2013, 14:3 (21 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Injury-elicited stressors alter endogenous retrovirus expression in lymphocytes depending on cell type and source lymphoid organ

Kang-Hoon Lee, Debora Lim, Tajia Green, David Greenhalgh, Kiho Cho BMC Immunology 2013, 14:2 (5 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Cytotoxic function of CD8+ T lymphocytes isolated from patients with acute severe cerebral infarction: an assessment of stroke-induced immunosuppression

Gang Li, Xin Wang, Li-hong Huang, Yue Wang, Jun-jie Hao, Xia Ge, Xiao-yun Xu BMC Immunology 2013, 14:1 (3 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum

Yuki Hitomi, Takahiro Adachi, Naoyuki Tsuchiya, Zen-Ichiro Honda, Katsushi Tokunaga, Takeshi Tsubata BMC Immunology 2012, 13:72 (26 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome

Hetty Prinsen, I Jolanda M de Vries, Ruurd Torensma, Jeanette M Pots, Sasja F Mulder, Carla M L van Herpen, Lammy D Elving, Gijs Bleijenberg, Foekje F Stelma, Hanneke W M van Laarhoven BMC Immunology 2012, 13:71 (17 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice

Chang-Qing Xia, Anna V Chernatynskaya, Clive H Wasserfall, Suigui Wan, Benjamin M Looney, Scott Eisenbeis, John Williams, Michael J Clare-Salzler, Mark A Atkinson BMC Immunology 2012, 13:70 (14 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden

Eva Källberg, Martin Stenström, David Liberg, Fredrik Ivars, Tomas Leanderson BMC Immunology 2012, 13:69 (12 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Identification and characterization of H-2d restricted CD4+ T cell epitopes on Lpp20 of Helicobacter pylori

Yan Li, Yin Jiang, Yue Xi, Lili Zhang, Jun Luo, Diandian He, Shuang Zeng, Yunshan Ning BMC Immunology 2012, 13:68 (12 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Sequence-based in silico analysis of well studied Hepatitis C Virus epitopes and their variants in other genotypes (particularly genotype 5a) against South African human leukocyte antigen backgrounds

Nishi Prabdial-Sing, Adrian J Puren, Sheila M Bowyer BMC Immunology 2012, 13:67 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The major CD8 T cell effector memory subset in the normal and Chlamydia trachomatis-infected human endocervix is low in perforin

Joyce A Ibana, Leann Myers, Constance Porretta, Maria Lewis, Stephanie N Taylor, David H Martin, Alison J Quayle BMC Immunology 2012, 13:66 (7 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Depletion of neutrophils in a protective model of pulmonary cryptococcosis results in increased IL-17A production by gamma/delta T cells

Karen L Wozniak, Jay K Kolls, Floyd L Wormley BMC Immunology 2012, 13:65 (7 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

The P2X7 loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels

Anke Wesselius, Martijn JL Bours, Ilja CW Arts, Esther HE Theunisz, Piet Geusens, Pieter C Dagnelie BMC Immunology 2012, 13:64 (4 December 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond

Olivier Garraud, Gwenoline Borhis, Gamal Badr, Séverine Degrelle, Bruno Pozzetto, Fabrice Cognasse, Yolande Richard BMC Immunology 2012, 13:63 (29 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Elevation of soluble major histocompatibility complex class I related chain A protein in malignant and infectious diseases in Chinese patients

Xiaoxin Jiang, Ju-Fang Huang, Zhi Huo, Qiuqui Zhang, Yan Jiang, Xiaoping Wu, Yanwen Li, Guanmin Jiang, Leping Zeng, Xiao-Xin Yan, Ping Yu, Renxian Cao BMC Immunology 2012, 13:62 (26 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine model

Rosanna Capparelli, Francesco De Chiara, Nunzia Nocerino, Rosa Montella, Marco Iannaccone, Andrea Fulgione, Alessandra Romanelli, Concetta Avitabile, Giuseppe Blaiotta, Federico Capuano BMC Immunology 2012, 13:61 (17 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat

Nils-Holger Zschemisch, Silke Glage, Dirk Wedekind, Edward J Weinstein, Xiaoxia Cui, Martina Dorsch, Hans-Jürgen Hedrich BMC Immunology 2012, 13:60 (8 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Zinc-finger nuclease mediated disruption of Rag1 produced a mutant rat with a complete depletion of mature B cells, hypoplastic thymus, and lack of lymphocytes in the spleen and lymph nodes, representing a potentially useful model for transplantation studies.

Research article   Open Access

Low-dose plasmid DNA treatment increases plasma vasopressin and regulates blood pressure in experimental endotoxemia

Thiago Malardo, Marcelo E Batalhão, Ademilson Panunto-Castelo, Luciana P Almeida, Everton Padilha, Isabela C Fontoura, Célio L Silva, Evelin C Carnio, Arlete AM Coelho-Castelo BMC Immunology 2012, 13:59 (8 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells

Guoying Wu, Keiji Hirabayashi, Shinya Sato, Nobuko Akiyama, Taishin Akiyama, Kunio Shiota, Shintaro Yagi BMC Immunology 2012, 13:58 (2 November 2012)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates

Paul J Groot-Kormelink, Lindsay Fawcett, Paul D Wright, Martin Gosling, Toby C Kent BMC Immunology 2012, 13:57 (26 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Important role of CCR2 in a murine model of coronary vasculitis

Hernan G Martinez, Marlon P Quinones, Fabio Jimenez, Carlos Estrada, Kassandra M Clark, Kazuo Suzuki, Noriko Miura, Naohito Ohno, Sunil K Ahuja, Seema S Ahuja BMC Immunology 2012, 13:56 (17 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Boosting immune response with the invariant chain segments via association with non-peptide binding region of major histocompatibility complex class II molecules

Fangfang Chen, Fantao Meng, Ling Pan, Fazhi Xu, Xuelan Liu, Weiyi Yu BMC Immunology 2012, 13:55 (27 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines

Song-yue Zheng, Bin Yu, Ke Zhang, Min Chen, Yan-Hong Hua, Shuofeng Yuan, Rory M Watt, Bo-Jian Zheng, Kwok-Yung Yuen, Jian-Dong Huang BMC Immunology 2012, 13:54 (26 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associated molecular pattern poly(I:C)

Julio Villena, Eriko Chiba, Yohsuke Tomosada, Susana Salva, Gabriela Marranzino, Haruki Kitazawa, Susana Alvarez BMC Immunology 2012, 13:53 (18 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Oral administration of the probiotic Lr1505 induces a mobilization of inflammatory cells and changes in the cytokine profile which beneficially modulate respiratory mucosal immunity and may offer a prophylactic defense against respiratory virus infection.

Research article   Open Access Highly Accessed

Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire

Peter A Larsen, Timothy P L Smith BMC Immunology 2012, 13:52 (14 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Characterization of functional mannose receptor in a continuous hybridoma cell line

David J Vigerust, Sherell Vick, Virginia L Shepherd BMC Immunology 2012, 13:51 (12 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction

Jun Huang, Yingnan Cao, Xianzhang Bu, Changyou Wu BMC Immunology 2012, 13:50 (10 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Responses to pandemic ASO3-adjuvanted A/California/07/09 H1N1 influenza vaccine in human immunodeficiency virus-infected individuals

Deborah Kelly, Kimberley Burt, Bayan Missaghi, Lisa Barrett, Yoav Keynan, Keith Fowke, Michael Grant BMC Immunology 2012, 13:49 (31 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Serum activity of DPPIV and its expression on lymphocytes in patients with melanoma and in people with vitiligo

Ivana Z Matić, Marija Đorđić, Nađa Grozdanić, Ana Damjanović, Branka Kolundžija, Aleksandra Erić-Nikolić, Radan Džodić, Miomir Šašić, Srđan Nikolić, Danijela Dobrosavljević, Sanvila Rašković, Slađana Andrejević, Dušica Gavrilović, Oscar J Cordero, Zorica D Juranić BMC Immunology 2012, 13:48 (21 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

In-vitro inhibition of IFNγ+ iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function

Volker Daniel, Mahmoud Sadeghi, Haihao Wang, Gerhard Opelz BMC Immunology 2012, 13:47 (21 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation

Ekta S Patel, Starlyn Okada, Kevin Hachey, Li-jun Yang, Scott K Durum, Jan S Moreb, Lung-Ji Chang BMC Immunology 2012, 13:46 (16 August 2012)

Abstract | Full text | PDF | PubMed

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