- Simon R Carding, University of Leeds
- Lucienne Chatenoud, Hospital Necker
- Olivier Garraud, Institut National de la Transfusion Sanguine
- Catherine M Hawrylowicz, King's College London
- James Li, University of Hong Kong
- J Philip McCoy, National Institutes of Health
- Christopher Morrey, BioMed Central
Analysis of venous blood from sepsis patients suggests that an early decrease in gene expression of TREM-1 in monocytes is associated with poor outcome and a reciprocal decrease of the surface receptor TREM-1 linked with sepsis-induced immunosuppression may be part of the explanation.
Studies in primary CD4+ T cells from mice suggest that lipid raft-based membrane order is critical for clonal expansion of CD4+ T cells in response to a model peptide.
A novel web based application ImmunoGlobulin Galaxy (IGGalaxy) can analyze next-generation sequencing results and report immunoglobulin heavy chain (IHG) gene rearrangements for both repertoire and clonality studies.
Unique and common gene sets, pathways, immune system categories and functional clusters of genes in four autoimmune diseases suggest it is possible to develop molecular classifications of autoimmune and inflammatory events.
Sara Montagner, Lorenzo Dehó1 and Silvia MonticelliBMC Immunology 2014, 15:14 (31 March 2014)
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Day of Immunology 2015
Published: 28 April 2015
Last updated: 29 April 2015
Current questions and challenges in infection and immunity
Edited by: Dr James Li, Prof Olivier Garraud
Published: 26 March 2015
Last updated: 29 May 2015
Section Editor's profile
Olivier Garraud is currently Professor of Immunology at the University of Lyon (the Faculty of Medicine of Saint-Etienne). Dr Garraud graduated as a physician and was trained in haematology and infectious diseases. He pursued his early career at the Institut Pasteur in Paris where he became involved with fundamental immunology. After more than a decade at the Institut Pasteur, Dr Garraud moved back to the field of medicine and was appointed the Executive Director of one of the 14 regional settings of the National Blood Service in France. Dr Garraud is currently supervising research programs focused on non-conventional B cell biology and platelet immunology in transfusion medicine but also in pathology, especially in infectious diseases such as sepsis, HIV infection and more generally in inflammation. Read more about his research interests in his recent review article.
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