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1.

11001
Accesses

Research article   Open Access Highly Accessed

Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes

Mari Palgi, Dario Greco, Riitta Lindström, Petri Auvinen, Tapio I Heino BMC Genomics 2012, 13:134 (11 April 2012)

Abstract | Full text | PDF | PubMed

2.

5510
Accesses

Research article   Open Access Highly Accessed

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.

3.

1913
Accesses

Research article   Open Access Highly Accessed

Comparative analysis of fungal genomes reveals different plant cell wall degrading capacity in fungi

Zhongtao Zhao, Huiquan Liu, Chenfang Wang, Jin-Rong Xu BMC Genomics 2013, 14:274 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

1829
Accesses

Research article   Open Access Highly Accessed

Genome analyses of the wheat yellow (stripe) rust pathogen Puccinia striiformis f. sp. tritici reveal polymorphic and haustorial expressed secreted proteins as candidate effectors

Dario Cantu, Vanesa Segovia, Daniel MacLean, Rosemary Bayles, Xianming Chen, Sophien Kamoun, Jorge Dubcovsky, Diane GO Saunders, Cristobal Uauy BMC Genomics 2013, 14:270 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

1816
Accesses

Research article   Open Access Highly Accessed

Gene promoters show chromosome-specificity and reveal chromosome territories in humans

Paul Gagniuc, Constantin Ionescu-Tirgoviste BMC Genomics 2013, 14:278 (24 April 2013)

Abstract | Provisional PDF | PubMed

6.

1573
Accesses

Methodology article   Open Access Highly Accessed

A data-driven approach to preprocessing Illumina 450K methylation array data

Ruth Pidsley, Chloe C Y Wong, Manuela Volta, Katie Lunnon, Jonathan Mill, Leonard C Schalkwyk BMC Genomics 2013, 14:293 (1 May 2013)

Abstract | Provisional PDF | PubMed

7.

1457
Accesses

Research article   Open Access Highly Accessed

LEA (Late Embryogenesis Abundant) proteins and their encoding genes in Arabidopsis thaliana

Michaela Hundertmark, Dirk K Hincha BMC Genomics 2008, 9:118 (4 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

1451
Accesses

Research article   Open Access

Characterization of human plasma-derived exosomal RNAs by deep sequencing

Xiaoyi Huang, Tiezheng Yuan, Michael Tschannen, Zhifu Sun, Howard Jacob, Meijun Du, Meihua Liang, Rachel L Dittmar, Yong Liu, Mingyu Liang, Manish Kohli, Stephen N Thibodeau, Lisa Boardman, Liang Wang BMC Genomics 2013, 14:319 (10 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

1364
Accesses

Software   Open Access Highly Accessed

ContigScape: a Cytoscape plugin facilitating microbial genome gap closing

Biao Tang, Qi Wang, Minjun Yang, Feng Xie, Yongqiang Zhu, Ying Zhuo, Shengyue Wang, Hong Gao, Xiaoming Ding, Lixin Zhang, Guoping Zhao, Huajun Zheng BMC Genomics 2013, 14:289 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

1242
Accesses

Research article   Open Access Highly Accessed

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

Colin Clarke, Michael Henry, Padraig Doolan, Shane Kelly, Sinead Aherne, Noelia Sanchez, Paul Kelly, Paula Kinsella, Laura Breen, Stephen F Madden, Lin Zhang, Mark Leonard, Martin Clynes, Paula Meleady, Niall Barron BMC Genomics 2012, 13:656 (21 November 2012)

Abstract | Full text | PDF | PubMed

11.

1239
Accesses

Research article   Open Access

Sequencing platform and library preparation choices impact viral metagenomes

Sergei A Solonenko, J Ignacio-Espinoza, Adriana Alberti, Corinne Cruaud, Steven Hallam, Kostas Konstantinidis, Gene Tyson, Patrick Wincker, Matthew B Sullivan BMC Genomics 2013, 14:320 (10 May 2013)

Abstract | Full text | PDF | PubMed

12.

1203
Accesses

Research article   Open Access Highly Accessed

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

Nicolas C Nalpas, Stephen DE Park, David A Magee, Maria Taraktsoglou, John A Browne, Kevin M Conlon, Kévin Rue-Albrecht, Kate E Killick, Karsten Hokamp, Amanda J Lohan, Brendan J Loftus, Eamonn Gormley, Stephen V Gordon, David E MacHugh BMC Genomics 2013, 14:230 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

1163
Accesses

Research article   Open Access Highly Accessed

Strand-specific RNA-seq reveals widespread occurrence of novel cis-natural antisense transcripts in rice

Tingting Lu, Chuanrang Zhu, Guojun Lu, Yunli Guo, Yan Zhou, Zhiyong Zhang, Yan Zhao, Wenjun Li, Ying Lu, Weihua Tang, Qi Feng, Bin Han BMC Genomics 2012, 13:721 (22 December 2012)

Abstract | Full text | PDF | PubMed

14.

1161
Accesses

Research article   Open Access Highly Accessed

Mapping of pigmentation QTL on an anchored genome assembly of the cichlid fish, Metriaclima zebra

Claire T O¿Quin, Alexi C Drilea, Matthew A Conte, Thomas D Kocher BMC Genomics 2013, 14:287 (27 April 2013)

Abstract | Provisional PDF | PubMed

15.

1156
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of differentially expressed genes during anther development in genetic male sterile and wild type cotton by digital gene-expression profiling

Mingming Wei, Meizhen Song, Shuli Fan, Shuxun Yu BMC Genomics 2013, 14:97 (12 February 2013)

Abstract | Full text | PDF | PubMed

16.

1141
Accesses

Research article   Open Access Highly Accessed

Genome-wide association study of sleep in Drosophila melanogaster

Susan T Harbison, Lenovia J McCoy, Trudy FC Mackay BMC Genomics 2013, 14:281 (25 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

1132
Accesses

Research article   Open Access Highly Accessed

Transcriptome analysis of Sacha Inchi (Plukenetia volubilis L.) seeds at two developmental stages

Xiaojuan Wang, Ronghua Xu, Ruling Wang, Aizhong Liu BMC Genomics 2012, 13:716 (20 December 2012)

Abstract | Full text | PDF | PubMed

18.

1132
Accesses

Research article   Open Access

Pause-melting misalignment: a novel model for the birth and motif indel of tandem repeats in the mitochondrial genome

Wei Shi, Xiao-Yu Kong, Zhong-Ming Wang, Shan-Shan Yu, Hai-Xia Chen, Elizabeth A De Stasio BMC Genomics 2013, 14:103 (15 February 2013)

Abstract | Full text | PDF | PubMed

19.

1149
Accesses

Methodology article   Open Access

Optimizing de novo assembly of short-read RNA-seq data for phylogenomics

Ya Yang, Stephen A Smith BMC Genomics 2013, 14:328 (14 May 2013)

Abstract | Provisional PDF | PubMed

20.

1082
Accesses

Research article   Open Access Highly Accessed

A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly

Warren R Francis, Lynne M Christianson, Rainer Kiko, Meghan L Powers, Nathan C Shaner, Steven H D Haddock BMC Genomics 2013, 14:167 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

21.

1081
Accesses

Research article   Open Access

Comparative genomic analysis of four representative plant growth-promoting rhizobacteria in Pseudomonas

Xuemei Shen, Hongbo Hu, Huasong Peng, Wei Wang, Xuehong Zhang BMC Genomics 2013, 14:271 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

22.

1069
Accesses

Research article   Open Access Highly Accessed

Draft genome sequence of the rubber tree Hevea brasiliensis

Ahmad Yamin Abdul Rahman, Abhilash O Usharraj, Biswapriya B Misra, Gincy P Thottathil, Kandakumar Jayasekaran, Yun Feng, Shaobin Hou, Su Yean Ong, Fui Ling Ng, Ling Sze Lee, Hock Siew Tan, Muhd Khairul Luqman Muhd Sakaff, Beng Soon Teh, Bee Khoo, Siti Suriawati Badai, Nurohaida Ab Aziz, Anton Yuryev, Bjarne Knudsen, Alexandre Dionne-Laporte, Nokuthula P Mchunu, Qingyi Yu, Brennick J Langston, Tracey Allen K Freitas, Aaron G Young, Rui Chen, Lei Wang, Nazalan Najimudin, Jennifer A Saito, Maqsudul Alam BMC Genomics 2013, 14:75 (2 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The draft genome of the rubber tree Hevea brasiliensis is almost 80% repetitive DNA with 12.7% of genes models identified being unique to this species, including key rubber biosynthesis and disease resistance genes

23.

1052
Accesses

Research article   Open Access

A consensus map of rapeseed (Brassica napus L.) based on diversity array technology markers: applications in genetic dissection of qualitative and quantitative traits

Harsh Raman, Rosy Raman, Andrzej Kilian, Frank Detering, Yan Long, David Edwards, Isobel AP Parkin, Andrew G Sharpe, Matthew N Nelson, Nick Larkan, Jun Zou, Jinling Meng, M Naveed Aslam, Jacqueline Batley, Wallace A Cowling, Derek Lydiate BMC Genomics 2013, 14:277 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

24.

1029
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of ‘Suli’ pear (Pyrus pyrifolia white pear group) buds during the dormancy by RNA-Seq

Guoqin Liu, Wanshun Li, Penghua Zheng, Tong Xu, Lijuan Chen, Dongfeng Liu, Sayed Hussain, Yuanwen Teng BMC Genomics 2012, 13:700 (12 December 2012)

Abstract | Full text | PDF | PubMed

25.

1027
Accesses

Reviewer acknowledgement   Open Access

Reviewer Acknowledgement 2012

Catherine M Rice BMC Genomics 2013, 14:231 (2 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

26.

1017
Accesses

Research article   Open Access Highly Accessed

Transcriptomic profiling of the salt-stress response in the wild recretohalophyte Reaumuria trigyna

Zhen-hua Dang, Lin-lin Zheng, Jia Wang, Zhe Gao, Shu-biao Wu, Zhi Qi, Ying-chun Wang BMC Genomics 2013, 14:29 (16 January 2013)

Abstract | Full text | PDF | PubMed

27.

1008
Accesses

Research article   Open Access

A microbial detection array (MDA) for viral and bacterial detection

Shea N Gardner, Crystal J Jaing, Kevin S McLoughlin, Tom R Slezak BMC Genomics 2010, 11:668 (25 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

1007
Accesses

Methodology article   Open Access Highly Accessed

Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes

Petr Dmitriev, Ana Barat, Anna Polesskaya, Mary J O’Connell, Thomas Robert, Philippe Dessen, Thomas A Walsh, Vladimir Lazar, Ahmed Turki, Gilles Carnac, Dalila Laoudj-Chenivesse, Marc Lipinski, Yegor S Vassetzky BMC Genomics 2013, 14:265 (18 April 2013)

Abstract | Full text | PDF | PubMed

29.

999
Accesses

Research article   Open Access

Origins of amyloid-β

William G Tharp, Indra Sarkar BMC Genomics 2013, 14:290 (30 April 2013)

Abstract | Full text | PDF | PubMed

30.

988
Accesses

Research article   Open Access Highly Accessed

Genome sequencing of bacteria: sequencing, de novo assembly and rapid analysis using open source tools

Veljo Kisand, Teresa Lettieri BMC Genomics 2013, 14:211 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

31.

962
Accesses

Research article   Open Access

Physiological stressors and invasive plant infections alter the small RNA transcriptome of the rice blast fungus, Magnaporthe oryzae

Vidhyavathi Raman, Stacey A Simon, Amanda Romag, Feray Demirci, Sandra M Mathioni, Jixian Zhai, Blake C Meyers, Nicole M Donofrio BMC Genomics 2013, 14:326 (12 May 2013)

Abstract | Full text | PDF | PubMed

32.

960
Accesses

Research article   Open Access

Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery

John A Lewis, Elizabeth A Gehman, Christine E Baer, David A Jackson BMC Genomics 2013, 14:291 (30 April 2013)

Abstract | Provisional PDF | PubMed

33.

951
Accesses

Research article   Open Access Highly Accessed

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

Robert Pinard, Alex de Winter, Gary J Sarkis, Mark B Gerstein, Karrie R Tartaro, Ramona N Plant, Michael Egholm, Jonathan M Rothberg, John H Leamon BMC Genomics 2006, 7:216 (23 August 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

34.

939
Accesses

Research article   Open Access Highly Accessed

Genome-wide promoter methylation profile of human testis and epididymis: identified from cell-free seminal DNA

Chunlin Wu, Xiaofang Ding, Honggang Li, Changhong Zhu, Chengliang Xiong BMC Genomics 2013, 14:288 (28 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

35.

909
Accesses

Research article   Open Access Highly Accessed

Transcriptional landscape of Aspergillus niger at breaking of conidial dormancy revealed by RNA-sequencing

Michaela Novodvorska, Kimran Hayer, Steven T Pullan, Raymond Wilson, Martin J Blythe, Hein Stam, Malcolm Stratford, David B Archer BMC Genomics 2013, 14:246 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

36.

895
Accesses

Research article   Open Access

Mitochondrial genomes and Doubly Uniparental Inheritance: new insights from Musculista senhousia sex-linked mitochondrial DNAs (Bivalvia Mytilidae)

Marco Passamonti, Andrea Ricci, Liliana Milani, Fabrizio Ghiselli BMC Genomics 2011, 12:442 (6 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

895
Accesses

Research article   Open Access

Transcriptome analysis of Cymbidium sinense and its application to the identification of genes associated with floral development

Jianxia Zhang, Kunlin Wu, Songjun Zeng, Jaime A Teixeira da Silva, Xiaolan Zhao, Chang-En Tian, Haoqiang Xia, Jun Duan BMC Genomics 2013, 14:279 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

38.

892
Accesses

Research article   Open Access

Sex-biased gene expression in the brown alga Fucus vesiculosus

Maria João F Martins, Catarina F Mota, Gareth A Pearson BMC Genomics 2013, 14:294 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

39.

883
Accesses

Research article   Open Access

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

Joseph M Dhahbi, Stephen R Spindler, Hani Atamna, Amy Yamakawa, Dario Boffelli, Patricia Mote, David IK Martin BMC Genomics 2013, 14:298 (2 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

40.

879
Accesses

Methodology article   Open Access

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

Alexis Christoforides, John D Carpten, Glen J Weiss, Michael J Demeure, Daniel D Von Hoff, David W Craig BMC Genomics 2013, 14:302 (4 May 2013)

Abstract | Provisional PDF | PubMed

41.

867
Accesses

Research article   Open Access Highly Accessed

Insights into the evolution of Darwin’s finches from comparative analysis of the Geospiza magnirostris genome sequence

Chris M Rands, Aaron Darling, Matthew Fujita, Lesheng Kong, Matthew T Webster, Céline Clabaut, Richard D Emes, Andreas Heger, Stephen Meader, Michael Brent Hawkins, Michael B Eisen, Clotilde Teiling, Jason Affourtit, Benjamin Boese, Peter R Grant, Barbara Rosemary Grant, Jonathan A Eisen, Arhat Abzhanov, Chris P Ponting BMC Genomics 2013, 14:95 (12 February 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

204 years after Charles Darwin’s birth, sequencing of the genome of the Darwin’s Finch Geospiza magnirostris reveals over 13,000 predicted genes, of which two under positive selection may have contributed to beak morphology evolution, which so interested Darwin.

42.

863
Accesses

Research article   Open Access

Functional genomic analysis of bile salt resistance in Enterococcus faecium

Xinglin Zhang, Damien Bierschenk, Janetta Top, Iacovos Anastasiou, Marc JM Bonten, Rob JL Willems, Willem van Schaik BMC Genomics 2013, 14:299 (3 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

43.

860
Accesses

Research article   Open Access

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response

Todd E White, Gregory D Ford, Monique C Surles-Zeigler, Alicia S Gates, Michelle C LaPlaca, Byron D Ford BMC Genomics 2013, 14:282 (25 April 2013)

Abstract | Provisional PDF | PubMed

44.

859
Accesses

Research article   Open Access

The Nocardia cyriacigeorgica GUH-2 genome shows ongoing adaptation of an environmental Actinobacteria to a pathogen's lifestyle

Anthony Zoropogui, Petar Pujic, Philippe Normand, Valérie Barbe, Patrick Belli, Arnault Graindorge, David Roche, David Vallenet, Sophie Mangenot, Patrick Boiron, Véronica Rodriguez-Nava, Sebastien Ribun, Yves Richard, Benoit Cournoyer, Didier Blaha BMC Genomics 2013, 14:286 (27 April 2013)

Abstract | Provisional PDF | PubMed

45.

849
Accesses

Research article   Open Access

Global remodeling of nucleosome positions in C. elegans

George Locke, Devorah Haberman, Steven M Johnson, Alexandre V Morozov BMC Genomics 2013, 14:284 (26 April 2013)

Abstract | Provisional PDF | PubMed

46.

832
Accesses

Expression of concern   Open Access Highly Accessed

Expression of concern: subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

Maria K Kowalczuk, Shreeya Nanda, Elizabeth C Moylan BMC Genomics 2013, 14:260 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

47.

830
Accesses

Research article   Open Access

A roadmap of cell-type specific gene expression during sequential stages of the arbuscular mycorrhiza symbiosis

Claudia Hogekamp, Helge Küster BMC Genomics 2013, 14:306 (7 May 2013)

Abstract | Provisional PDF | PubMed

48.

830
Accesses

Methodology article   Open Access

A simple and reproducible breast cancer prognostic test

Luigi Marchionni, Bahman Afsari, Donald Geman, Jeffrey T Leek BMC Genomics 2013, 14:336 (17 May 2013)

Abstract | Provisional PDF

49.

803
Accesses

Research article   Open Access Highly Accessed

RAD tag sequencing as a source of SNP markers in Cynara cardunculus L

Davide Scaglione, Alberto Acquadro, Ezio Portis, Matteo Tirone, Steven J Knapp, Sergio Lanteri BMC Genomics 2012, 13:3 (3 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

801
Accesses

Research article   Open Access

Study of whole genome linkage disequilibrium in Nellore cattle

Rafael Espigolan, Fernando Baldi, Arione A Boligon, Fabio RP Souza, Daniel GM Gordo, Rafael L Tonussi, Diércles F Cardoso, Henrique N Oliveira, Humberto Tonhati, Mehdi Sargolzaei, Flavio S Schenkel, Roberto Carvalheiro, Jesus A Ferro, Lucia G Albuquerque BMC Genomics 2013, 14:305 (5 May 2013)

Abstract | Provisional PDF | PubMed

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