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1.

9047
Accesses

Research article   Open Access Highly Accessed

Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes

Mari Palgi, Dario Greco, Riitta Lindström, Petri Auvinen, Tapio I Heino BMC Genomics 2012, 13:134 (11 April 2012)

Abstract | Full text | PDF | PubMed

2.

5594
Accesses

Research article   Open Access Highly Accessed

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.

3.

1844
Accesses

Research article   Open Access Highly Accessed

Comparative analysis of fungal genomes reveals different plant cell wall degrading capacity in fungi

Zhongtao Zhao, Huiquan Liu, Chenfang Wang, Jin-Rong Xu BMC Genomics 2013, 14:274 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

1778
Accesses

Research article   Open Access Highly Accessed

Genome analyses of the wheat yellow (stripe) rust pathogen Puccinia striiformis f. sp. tritici reveal polymorphic and haustorial expressed secreted proteins as candidate effectors

Dario Cantu, Vanesa Segovia, Daniel MacLean, Rosemary Bayles, Xianming Chen, Sophien Kamoun, Jorge Dubcovsky, Diane GO Saunders, Cristobal Uauy BMC Genomics 2013, 14:270 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

1765
Accesses

Research article   Open Access Highly Accessed

Gene promoters show chromosome-specificity and reveal chromosome territories in humans

Paul Gagniuc, Constantin Ionescu-Tirgoviste BMC Genomics 2013, 14:278 (24 April 2013)

Abstract | Provisional PDF | PubMed

6.

1613
Accesses

Research article   Open Access Highly Accessed

LEA (Late Embryogenesis Abundant) proteins and their encoding genes in Arabidopsis thaliana

Michaela Hundertmark, Dirk K Hincha BMC Genomics 2008, 9:118 (4 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

1462
Accesses

Methodology article   Open Access Highly Accessed

A data-driven approach to preprocessing Illumina 450K methylation array data

Ruth Pidsley, Chloe C Y Wong, Manuela Volta, Katie Lunnon, Jonathan Mill, Leonard C Schalkwyk BMC Genomics 2013, 14:293 (1 May 2013)

Abstract | Provisional PDF | PubMed

8.

1321
Accesses

Research article   Open Access Highly Accessed

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

Nicolas C Nalpas, Stephen DE Park, David A Magee, Maria Taraktsoglou, John A Browne, Kevin M Conlon, Kévin Rue-Albrecht, Kate E Killick, Karsten Hokamp, Amanda J Lohan, Brendan J Loftus, Eamonn Gormley, Stephen V Gordon, David E MacHugh BMC Genomics 2013, 14:230 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

1309
Accesses

Research article   Open Access Highly Accessed

Strand-specific RNA-seq reveals widespread occurrence of novel cis-natural antisense transcripts in rice

Tingting Lu, Chuanrang Zhu, Guojun Lu, Yunli Guo, Yan Zhou, Zhiyong Zhang, Yan Zhao, Wenjun Li, Ying Lu, Weihua Tang, Qi Feng, Bin Han BMC Genomics 2012, 13:721 (22 December 2012)

Abstract | Full text | PDF | PubMed

10.

1311
Accesses

Software   Open Access Highly Accessed

ContigScape: a Cytoscape plugin facilitating microbial genome gap closing

Biao Tang, Qi Wang, Minjun Yang, Feng Xie, Yongqiang Zhu, Ying Zhuo, Shengyue Wang, Hong Gao, Xiaoming Ding, Lixin Zhang, Guoping Zhao, Huajun Zheng BMC Genomics 2013, 14:289 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

1276
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of differentially expressed genes during anther development in genetic male sterile and wild type cotton by digital gene-expression profiling

Mingming Wei, Meizhen Song, Shuli Fan, Shuxun Yu BMC Genomics 2013, 14:97 (12 February 2013)

Abstract | Full text | PDF | PubMed

12.

1264
Accesses

Research article   Open Access Highly Accessed

Transcriptome analysis of Sacha Inchi (Plukenetia volubilis L.) seeds at two developmental stages

Xiaojuan Wang, Ronghua Xu, Ruling Wang, Aizhong Liu BMC Genomics 2012, 13:716 (20 December 2012)

Abstract | Full text | PDF | PubMed

13.

1242
Accesses

Methodology article   Open Access Highly Accessed

Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes

Petr Dmitriev, Ana Barat, Anna Polesskaya, Mary J O’Connell, Thomas Robert, Philippe Dessen, Thomas A Walsh, Vladimir Lazar, Ahmed Turki, Gilles Carnac, Dalila Laoudj-Chenivesse, Marc Lipinski, Yegor S Vassetzky BMC Genomics 2013, 14:265 (18 April 2013)

Abstract | Full text | PDF | PubMed

14.

1236
Accesses

Research article   Open Access Highly Accessed

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

Colin Clarke, Michael Henry, Padraig Doolan, Shane Kelly, Sinead Aherne, Noelia Sanchez, Paul Kelly, Paula Kinsella, Laura Breen, Stephen F Madden, Lin Zhang, Mark Leonard, Martin Clynes, Paula Meleady, Niall Barron BMC Genomics 2012, 13:656 (21 November 2012)

Abstract | Full text | PDF | PubMed

15.

1180
Accesses

Research article   Open Access

Characterization of human plasma-derived exosomal RNAs by deep sequencing

Xiaoyi Huang, Tiezheng Yuan, Michael Tschannen, Zhifu Sun, Howard Jacob, Meijun Du, Meihua Liang, Rachel L Dittmar, Yong Liu, Mingyu Liang, Manish Kohli, Stephen N Thibodeau, Lisa Boardman, Liang Wang BMC Genomics 2013, 14:319 (10 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

1165
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of ‘Suli’ pear (Pyrus pyrifolia white pear group) buds during the dormancy by RNA-Seq

Guoqin Liu, Wanshun Li, Penghua Zheng, Tong Xu, Lijuan Chen, Dongfeng Liu, Sayed Hussain, Yuanwen Teng BMC Genomics 2012, 13:700 (12 December 2012)

Abstract | Full text | PDF | PubMed

17.

1140
Accesses

Research article   Open Access Highly Accessed

Transcriptomic profiling of the salt-stress response in the wild recretohalophyte Reaumuria trigyna

Zhen-hua Dang, Lin-lin Zheng, Jia Wang, Zhe Gao, Shu-biao Wu, Zhi Qi, Ying-chun Wang BMC Genomics 2013, 14:29 (16 January 2013)

Abstract | Full text | PDF | PubMed

18.

1117
Accesses

Research article   Open Access Highly Accessed

Genome-wide association study of sleep in Drosophila melanogaster

Susan T Harbison, Lenovia J McCoy, Trudy FC Mackay BMC Genomics 2013, 14:281 (25 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

1105
Accesses

Research article   Open Access Highly Accessed

Mapping of pigmentation QTL on an anchored genome assembly of the cichlid fish, Metriaclima zebra

Claire T O¿Quin, Alexi C Drilea, Matthew A Conte, Thomas D Kocher BMC Genomics 2013, 14:287 (27 April 2013)

Abstract | Provisional PDF | PubMed

20.

1097
Accesses

Research article   Open Access Highly Accessed

A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly

Warren R Francis, Lynne M Christianson, Rainer Kiko, Meghan L Powers, Nathan C Shaner, Steven H D Haddock BMC Genomics 2013, 14:167 (12 March 2013)

Abstract | Full text | PDF | PubMed

21.

1092
Accesses

Research article   Open Access Highly Accessed

Genome sequencing of bacteria: sequencing, de novo assembly and rapid analysis using open source tools

Veljo Kisand, Teresa Lettieri BMC Genomics 2013, 14:211 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

22.

1083
Accesses

Expression of concern   Open Access Highly Accessed

Expression of concern: subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

Maria K Kowalczuk, Shreeya Nanda, Elizabeth C Moylan BMC Genomics 2013, 14:260 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

1075
Accesses

Research article   Open Access

Pause-melting misalignment: a novel model for the birth and motif indel of tandem repeats in the mitochondrial genome

Wei Shi, Xiao-Yu Kong, Zhong-Ming Wang, Shan-Shan Yu, Hai-Xia Chen, Elizabeth A De Stasio BMC Genomics 2013, 14:103 (15 February 2013)

Abstract | Full text | PDF | PubMed

24.

1069
Accesses

Research article   Open Access

A microbial detection array (MDA) for viral and bacterial detection

Shea N Gardner, Crystal J Jaing, Kevin S McLoughlin, Tom R Slezak BMC Genomics 2010, 11:668 (25 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

1079
Accesses

Research article   Open Access

Sequencing platform and library preparation choices impact viral metagenomes

Sergei A Solonenko, J Ignacio-Espinoza, Adriana Alberti, Corinne Cruaud, Steven Hallam, Kostas Konstantinidis, Gene Tyson, Patrick Wincker, Matthew B Sullivan BMC Genomics 2013, 14:320 (10 May 2013)

Abstract | Full text | PDF | PubMed

26.

1044
Accesses

Research article   Open Access

Comparative genomic analysis of four representative plant growth-promoting rhizobacteria in Pseudomonas

Xuemei Shen, Hongbo Hu, Huasong Peng, Wei Wang, Xuehong Zhang BMC Genomics 2013, 14:271 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

27.

1041
Accesses

Research article   Open Access Highly Accessed

Draft genome sequence of the rubber tree Hevea brasiliensis

Ahmad Yamin Abdul Rahman, Abhilash O Usharraj, Biswapriya B Misra, Gincy P Thottathil, Kandakumar Jayasekaran, Yun Feng, Shaobin Hou, Su Yean Ong, Fui Ling Ng, Ling Sze Lee, Hock Siew Tan, Muhd Khairul Luqman Muhd Sakaff, Beng Soon Teh, Bee Khoo, Siti Suriawati Badai, Nurohaida Ab Aziz, Anton Yuryev, Bjarne Knudsen, Alexandre Dionne-Laporte, Nokuthula P Mchunu, Qingyi Yu, Brennick J Langston, Tracey Allen K Freitas, Aaron G Young, Rui Chen, Lei Wang, Nazalan Najimudin, Jennifer A Saito, Maqsudul Alam BMC Genomics 2013, 14:75 (2 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The draft genome of the rubber tree Hevea brasiliensis is almost 80% repetitive DNA with 12.7% of genes models identified being unique to this species, including key rubber biosynthesis and disease resistance genes

28.

1036
Accesses

Research article   Open Access

Mitochondrial genomes and Doubly Uniparental Inheritance: new insights from Musculista senhousia sex-linked mitochondrial DNAs (Bivalvia Mytilidae)

Marco Passamonti, Andrea Ricci, Liliana Milani, Fabrizio Ghiselli BMC Genomics 2011, 12:442 (6 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

1024
Accesses

Research article   Open Access

A consensus map of rapeseed (Brassica napus L.) based on diversity array technology markers: applications in genetic dissection of qualitative and quantitative traits

Harsh Raman, Rosy Raman, Andrzej Kilian, Frank Detering, Yan Long, David Edwards, Isobel AP Parkin, Andrew G Sharpe, Matthew N Nelson, Nick Larkan, Jun Zou, Jinling Meng, M Naveed Aslam, Jacqueline Batley, Wallace A Cowling, Derek Lydiate BMC Genomics 2013, 14:277 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

30.

1011
Accesses

Research article   Open Access Highly Accessed

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

Robert Pinard, Alex de Winter, Gary J Sarkis, Mark B Gerstein, Karrie R Tartaro, Ramona N Plant, Michael Egholm, Jonathan M Rothberg, John H Leamon BMC Genomics 2006, 7:216 (23 August 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

31.

1007
Accesses

Research article   Open Access Highly Accessed

Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

Sebastiaan van Heesch, Wigard P Kloosterman, Nico Lansu, Frans-Paul Ruzius, Elizabeth Levandowsky, Clarence C Lee, Shiguo Zhou, Steve Goldstein, David C Schwartz, Timothy T Harkins, Victor Guryev, Edwin Cuppen BMC Genomics 2013, 14:257 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

32.

1004
Accesses

Reviewer acknowledgement   Open Access

Reviewer Acknowledgement 2012

Catherine M Rice BMC Genomics 2013, 14:231 (2 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

33.

952
Accesses

Research article   Open Access Highly Accessed

Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver

Jonathan Schug, Lindsay B McKenna, Gabriel Walton, Nicholas Hand, Sarmistha Mukherjee, Kow Essuman, Zhongjie Shi, Yan Gao, Karen Markley, Momo Nakagawa, Vasumathi Kameswaran, Anastassios Vourekas, Joshua R Friedman, Klaus H Kaestner, Linda E Greenbaum BMC Genomics 2013, 14:264 (18 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

34.

942
Accesses

Research article   Open Access

Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery

John A Lewis, Elizabeth A Gehman, Christine E Baer, David A Jackson BMC Genomics 2013, 14:291 (30 April 2013)

Abstract | Provisional PDF | PubMed

35.

928
Accesses

Research article   Open Access

Origins of amyloid-beta

William G Tharp, Indra Neil Sarkar BMC Genomics 2013, 14:290 (30 April 2013)

Abstract | Provisional PDF | PubMed

36.

911
Accesses

Research article   Open Access Highly Accessed

Transcriptional landscape of Aspergillus niger at breaking of conidial dormancy revealed by RNA-sequencing

Michaela Novodvorska, Kimran Hayer, Steven T Pullan, Raymond Wilson, Martin J Blythe, Hein Stam, Malcolm Stratford, David B Archer BMC Genomics 2013, 14:246 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

37.

898
Accesses

Research article   Open Access Highly Accessed

Insights into the evolution of Darwin’s finches from comparative analysis of the Geospiza magnirostris genome sequence

Chris M Rands, Aaron Darling, Matthew Fujita, Lesheng Kong, Matthew T Webster, Céline Clabaut, Richard D Emes, Andreas Heger, Stephen Meader, Michael Brent Hawkins, Michael B Eisen, Clotilde Teiling, Jason Affourtit, Benjamin Boese, Peter R Grant, Barbara Rosemary Grant, Jonathan A Eisen, Arhat Abzhanov, Chris P Ponting BMC Genomics 2013, 14:95 (12 February 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

204 years after Charles Darwin’s birth, sequencing of the genome of the Darwin’s Finch Geospiza magnirostris reveals over 13,000 predicted genes, of which two under positive selection may have contributed to beak morphology evolution, which so interested Darwin.

38.

897
Accesses

Research article   Open Access

Characterization of differential transcript abundance through time during Nematostella vectensis development

Rebecca Rae Helm, Stefan Siebert, Sarah Tulin, Joel Smith, Casey William Dunn BMC Genomics 2013, 14:266 (19 April 2013)

Abstract | Provisional PDF | PubMed

39.

898
Accesses

Research article   Open Access Highly Accessed

Genome-wide promoter methylation profile of human testis and epididymis: identified from cell-free seminal DNA

Chunlin Wu, Xiaofang Ding, Honggang Li, Changhong Zhu, Chengliang Xiong BMC Genomics 2013, 14:288 (28 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

40.

870
Accesses

Research article   Open Access

Transcriptome characterisation of Pinus tabuliformis and evolution of genes in the Pinus phylogeny

Shi-Hui Niu, Zhe-Xin Li, Hu-Wei Yuan, Xiao-Yang Chen, Yue Li, Wei Li BMC Genomics 2013, 14:263 (18 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

41.

854
Accesses

Research article   Open Access Highly Accessed

Genome-wide identification, characterization, and expression analysis of lineage-specific genes within zebrafish

Liandong Yang, Ming Zou, Beide Fu, Shunping He BMC Genomics 2013, 14:65 (31 January 2013)

Abstract | Full text | PDF | PubMed

42.

853
Accesses

Research article   Open Access

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

Joseph M Dhahbi, Stephen R Spindler, Hani Atamna, Amy Yamakawa, Dario Boffelli, Patricia Mote, David IK Martin BMC Genomics 2013, 14:298 (2 May 2013)

Abstract | Full text | PDF | PubMed

43.

852
Accesses

Research article   Open Access

Transcriptome analysis of Cymbidium sinense and its application to the identification of genes associated with floral development

Jianxia Zhang, Kunlin Wu, Songjun Zeng, Jaime A Teixeira da Silva, Xiaolan Zhao, Chang-En Tian, Haoqiang Xia, Jun Duan BMC Genomics 2013, 14:279 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

44.

849
Accesses

Research article   Open Access

Sex-biased gene expression in the brown alga Fucus vesiculosus

Maria João F Martins, Catarina F Mota, Gareth A Pearson BMC Genomics 2013, 14:294 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

45.

847
Accesses

Research article   Open Access

The Nocardia cyriacigeorgica GUH-2 genome shows ongoing adaptation of an environmental Actinobacteria to a pathogen's lifestyle

Anthony Zoropogui, Petar Pujic, Philippe Normand, Valérie Barbe, Patrick Belli, Arnault Graindorge, David Roche, David Vallenet, Sophie Mangenot, Patrick Boiron, Véronica Rodriguez-Nava, Sebastien Ribun, Yves Richard, Benoit Cournoyer, Didier Blaha BMC Genomics 2013, 14:286 (27 April 2013)

Abstract | Provisional PDF | PubMed

46.

843
Accesses

Research article   Open Access Highly Accessed

RAD tag sequencing as a source of SNP markers in Cynara cardunculus L

Davide Scaglione, Alberto Acquadro, Ezio Portis, Matteo Tirone, Steven J Knapp, Sergio Lanteri BMC Genomics 2012, 13:3 (3 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

843
Accesses

Research article   Open Access

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response

Todd E White, Gregory D Ford, Monique C Surles-Zeigler, Alicia S Gates, Michelle C LaPlaca, Byron D Ford BMC Genomics 2013, 14:282 (25 April 2013)

Abstract | Provisional PDF | PubMed

48.

842
Accesses

Methodology article   Open Access

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

Alexis Christoforides, John D Carpten, Glen J Weiss, Michael J Demeure, Daniel D Von Hoff, David W Craig BMC Genomics 2013, 14:302 (4 May 2013)

Abstract | Provisional PDF | PubMed

49.

841
Accesses

Research article   Open Access

Functional genomic analysis of bile salt resistance in Enterococcus faecium

Xinglin Zhang, Damien Bierschenk, Janetta Top, Iacovos Anastasiou, Marc JM Bonten, Rob JL Willems, Willem van Schaik BMC Genomics 2013, 14:299 (3 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

50.

837
Accesses

Research article   Open Access Highly Accessed

Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence

Benoît Remenant, Bénédicte Coupat-Goutaland, Alice Guidot, Gilles Cellier, Emmanuel Wicker, Caitilyn Allen, Mark Fegan, Olivier Pruvost, Mounira Elbaz, Alexandra Calteau, Gregory Salvignol, Damien Mornico, Sophie Mangenot, Valérie Barbe, Claudine Médigue, Philippe Prior BMC Genomics 2010, 11:379 (15 June 2010)

Abstract | Full text | PDF | PubMed

51.

831
Accesses

Research article   Open Access Highly Accessed

How deep is deep enough for RNA-Seq profiling of bacterial transcriptomes?

Brian J Haas, Melissa Chin, Chad Nusbaum, Bruce W Birren, Jonathan Livny BMC Genomics 2012, 13:734 (27 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

52.

829
Accesses

Research article   Open Access Highly Accessed

Genome-wide identification of soybean microRNAs and their targets reveals their organ-specificity and responses to phosphate starvation

Feng Xu, Qian Liu, Luying Chen, Jiebin Kuang, Thomas Walk, Jinxiang Wang, Hong Liao BMC Genomics 2013, 14:66 (31 January 2013)

Abstract | Provisional PDF | PubMed

53.

828
Accesses

Research article   Open Access Highly Accessed

Conserved microstructure of the Brassica B Genome of Brassica nigra in relation to homologous regions of Arabidopsis thaliana, B. rapa and B. oleracea

Zahra-Katy Navabi, Terry Huebert, Andrew G Sharpe, Carmel M O¿Neill, Ian Bancroft, Isobel AP Parkin BMC Genomics 2013, 14:250 (15 April 2013)

Abstract | Provisional PDF | PubMed

54.

819
Accesses

Research article   Open Access Highly Accessed

Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito

Che Julius Ngwa, Matthias Scheuermayer, Gunnar Rudolf Mair, Selina Kern, Thomas Brügl, Christine Clara Wirth, Makoah Nigel Aminake, Jochen Wiesner, Rainer Fischer, Andreas Vilcinskas, Gabriele Pradel BMC Genomics 2013, 14:256 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

55.

825
Accesses

Research article   Open Access

Transcriptome analysis of the Cryptocaryon irritans tomont stage identifies potential genes for the detection and control of cryptocaryonosis

Yogeswaran Lokanathan, Adura Mohd-Adnan, Kiew-Lian Wan, Sheila Nathan BMC Genomics 2010, 11:76 (29 January 2010)

Abstract | Full text | PDF | PubMed

56.

822
Accesses

Research article   Open Access

Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

Ariel Fernández, Yun-Huei Tzeng, Sze-Bi Hsu BMC Genomics 2011, 12:604 (14 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

57.

800
Accesses

Research article   Open Access

miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells

Davide Barbagallo, Salvatore Piro, Angelo G Condorelli, Loriana G Mascali, Francesca Urbano, Nunziatina Parrinello, Adelina Monello, Luisa Statello, Marco Ragusa, Agata M Rabuazzo, Cinzia Di Pietro, Francesco Purrello, Michele Purrello BMC Genomics 2013, 14:62 (29 January 2013)

Abstract | Full text | PDF | PubMed

58.

800
Accesses

Research article   Open Access

Global remodeling of nucleosome positions in C. elegans

George Locke, Devorah Haberman, Steven M Johnson, Alexandre V Morozov BMC Genomics 2013, 14:284 (26 April 2013)

Abstract | Provisional PDF | PubMed

59.

790
Accesses

Research article   Open Access

A roadmap of cell-type specific gene expression during sequential stages of the arbuscular mycorrhiza symbiosis

Claudia Hogekamp, Helge Küster BMC Genomics 2013, 14:306 (7 May 2013)

Abstract | Provisional PDF | PubMed

60.

785
Accesses

Software   Open Access

P2RP: a web-based framework for the identification and analysis of regulatory proteins in prokaryotic genomes

Mohamed Barakat, Philippe Ortet, David E Whitworth BMC Genomics 2013, 14:269 (20 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

61.

784
Accesses

Methodology article   Open Access

Transcriptome screen for fast evolving genes by Inter-Specific Selective Hybridization (ISSH)

Juan I Montoya-Burgos, Aurélia Foulon, Ilham Bahechar BMC Genomics 2010, 11:126 (22 February 2010)

Abstract | Full text | PDF | PubMed

62.

784
Accesses

Research   Open Access

New methods for separating causes from effects in genomics data

Alexander Statnikov, Mikael Henaff, Nikita I Lytkin, Constantin F Aliferis BMC Genomics 2012, 13(Suppl 8):S22 (17 December 2012)

Abstract | Full text | PDF | PubMed

63.

777
Accesses

Research article   Open Access

A microsatellite-based linkage map of salt tolerant tilapia (Oreochromis mossambicus x Oreochromis spp.) and mapping of sex-determining loci

Feng Liu, Fei Sun, Jian Li, Jun Hong Xia, Grace Lin, Rong Jian Tu, Gen Hua Yue BMC Genomics 2013, 14:58 (28 January 2013)

Abstract | Full text | PDF | PubMed

64.

767
Accesses

Research article   Open Access Highly Accessed

Low-pass sequencing for microbial comparative genomics

Young Ah Goo, Jared Roach, Gustavo Glusman, Nitin S Baliga, Kerry Deutsch, Min Pan, Sean Kennedy, Shiladitya DasSarma, Wailap Victor Ng, Leroy Hood BMC Genomics 2004, 5:3 (12 January 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Low-pass shotgun sequencing of four extreme halophiles yields surprisingly useful information, including a family tree, when it is compared with the completed sequence of another Halobacterium.

65.

762
Accesses

Research article   Open Access

High-density SNP-based genetic map development and linkage disequilibrium assessment in Brassica napus L

Régine Delourme, Cyril Falentin, Berline Fomeju, Marie Boillot, Gilles Lassalle, Isabelle André, Jorge Duarte, Valérie Gauthier, Nicole Lucante, Amandine Marty, Maryline Pauchon, Jean-Philippe Pichon, Nicolas Ribière, Gwenn Trotoux, Philippe Blanchard, Nathalie Rivière, Jean-Pierre Martinant, Jérôme Pauquet BMC Genomics 2013, 14:120 (22 February 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

66.

762
Accesses

Research article   Open Access Highly Accessed

Comparing de novo assemblers for 454 transcriptome data

Sujai Kumar, Mark L Blaxter BMC Genomics 2010, 11:571 (16 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

67.

760
Accesses

Research article   Open Access

Transcriptional analysis of the three Nlrp1 paralogs in mice

Inka Sastalla, Devorah Crown, Seth L Masters, Andrew McKenzie, Stephen H Leppla, Mahtab Moayeri BMC Genomics 2013, 14:188 (18 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

68.

758
Accesses

Research article   Open Access

Study of whole genome linkage disequilibrium in Nellore cattle

Rafael Espigolan, Fernando Baldi, Arione A Boligon, Fabio RP Souza, Daniel GM Gordo, Rafael L Tonussi, Diércles F Cardoso, Henrique N Oliveira, Humberto Tonhati, Mehdi Sargolzaei, Flavio S Schenkel, Roberto Carvalheiro, Jesus A Ferro, Lucia G Albuquerque BMC Genomics 2013, 14:305 (5 May 2013)

Abstract | Provisional PDF | PubMed

69.

755
Accesses

Methodology article   Open Access Highly Accessed

Rapid, scalable and highly automated HLA genotyping using next-generation sequencing: a transition from research to diagnostics

Martin Danzer, Norbert Niklas, Stephanie Stabentheiner, Katja Hofer, Johannes Pröll, Christina Stückler, Edeltraud Raml, Helene Polin, Christian Gabriel BMC Genomics 2013, 14:221 (4 April 2013)

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A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

Jennifer Summers McKinney, Sunaina Sethi, Jennifer DeMars Tripp, Thuy N Nguyen, Brian A Sanderson, James W Westmoreland, Michael A Resnick, L Kevin Lewis BMC Genomics 2013, 14:251 (15 April 2013)

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Unscrambling butterfly oogenesis

Jean-Michel Carter, Simon C Baker, Ryan Pink, David RF Carter, Aiden Collins, Jeremie Tomlin, Melanie Gibbs, Casper J Breuker BMC Genomics 2013, 14:283 (26 April 2013)

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Pig immune response to general stimulus and to porcine reproductive and respiratory syndrome virus infection: a meta-analysis approach

Bouabid Badaoui, Christopher K Tuggle, Zhiliang Hu, James M Reecy, Tahar Ait-Ali, Anna Anselmo, Sara Botti BMC Genomics 2013, 14:220 (3 April 2013)

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Short and long-term genome stability analysis of prokaryotic genomes

Matteo Brilli, Pietro Liò, Vincent Lacroix, Marie-France Sagot BMC Genomics 2013, 14:309 (8 May 2013)

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Prediction and identification of natural antisense transcripts and their small RNAs in soybean (Glycine max)

Hu Zheng, Jiang Qiyan, Ni Zhiyong, Zhang Hui BMC Genomics 2013, 14:280 (24 April 2013)

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Functional transcriptomic analysis of the role of MAB-5/Hox in Q neuroblast migration in Caenorhabditis elegans

Joel V Tamayo, Mahekta Gujar, Stuart J Macdonald, Erik A Lundquist BMC Genomics 2013, 14:304 (4 May 2013)

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The RAST Server: Rapid Annotations using Subsystems Technology

Ramy K Aziz, Daniela Bartels, Aaron A Best, Matthew DeJongh, Terrence Disz, Robert A Edwards, Kevin Formsma, Svetlana Gerdes, Elizabeth M Glass, Michael Kubal, Folker Meyer, Gary J Olsen, Robert Olson, Andrei L Osterman, Ross A Overbeek, Leslie K McNeil, Daniel Paarmann, Tobias Paczian, Bruce Parrello, Gordon D Pusch, Claudia Reich, Rick Stevens, Olga Vassieva, Veronika Vonstein, Andreas Wilke, Olga Zagnitko BMC Genomics 2008, 9:75 (8 February 2008)

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Massively-parallel sequencing of genes on a single chromosome: a comparison of solution hybrid selection and flow sorting

Jamie K Teer, Jennifer J Johnston, Sarah L Anzick, Marbin Pineda, Gary Stone, NISC Comparative Sequencing Program1, Paul S Meltzer, James C Mullikin, Leslie G Biesecker BMC Genomics 2013, 14:253 (15 April 2013)

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Physiological stressors and invasive plant infections alter the small RNA transcriptome of the rice blast fungus, Magnaporthe oryzae

Vidhyavathi Raman, Stacey A Simon, Amanda Romag, Feray Demirci, Sandra M Mathioni, Jixian Zhai, Blake C Meyers, Nicole M Donofrio BMC Genomics 2013, 14:326 (12 May 2013)

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Optimizing illumina next-generation sequencing library preparation for extremely at-biased genomes

Samuel O Oyola, Thomas D Otto, Yong Gu, Gareth Maslen, Magnus Manske, Susana Campino, Daniel J Turner, Bronwyn MacInnis, Dominic P Kwiatkowski, Harold P Swerdlow, Michael A Quail BMC Genomics 2012, 13:1 (3 January 2012)

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Venom gland transcriptomes of two elapid snakes (Bungarus multicinctus and Naja atra) and evolution of toxin genes

Yu Jiang, Yan Li, Wenhui Lee, Xun Xu, Yue Zhang, Ruoping Zhao, Yun Zhang, Wen Wang BMC Genomics 2011, 12:1 (3 January 2011)

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Gene-based single nucleotide polymorphism discovery in bovine muscle using next-generation transcriptomic sequencing

Anis Djari, Diane Esquerré, Bernard Weiss, Frédéric Martins, Cédric Meersseman, Mekki Boussaha, Christophe Klopp, Dominique Rocha BMC Genomics 2013, 14:307 (7 May 2013)

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High natural gene expression variation in the reef-building coral Acropora millepora: potential for acclimative and adaptive plasticity

Camila Granados-Cifuentes, Anthony J Bellantuono, Tyrone Ridgway, Ove Hoegh-Guldberg, Mauricio Rodriguez-Lanetty BMC Genomics 2013, 14:228 (8 April 2013)

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Six novel Y chromosome genes in Anopheles mosquitoes discovered by independently sequencing males and females

Andrew Brantley Hall, Yumin Qi, Vladimir Timoshevskiy, Maria V Sharakhova, Igor V Sharakhov, Zhijian Tu BMC Genomics 2013, 14:273 (23 April 2013)

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Comparative gene expression between two yeast species

Yuanfang Guan, Maitreya J Dunham, Olga G Troyanskaya, Amy A Caudy BMC Genomics 2013, 14:33 (16 January 2013)

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RNAseq versus genome-predicted transcriptomes: a large population of novel transcripts identified in an Illumina-454 Hydra transcriptome

Yvan Wenger, Brigitte Galliot BMC Genomics 2013, 14:204 (25 March 2013)

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Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

Kumpei Tanisawa, Eri Mikami, Noriyuki Fuku, Yoko Honda, Shuji Honda, Ikuro Ohsawa, Masafumi Ito, Shogo Endo, Kunio Ihara, Kinji Ohno, Yuki Kishimoto, Akihito Ishigami, Naoki Maruyama, Motoji Sawabe, Hiroyoshi Iseki, Yasushi Okazaki, Sanae Hasegawa-Ishii, Shiro Takei, Atsuyoshi Shimada, Masanori Hosokawa, Masayuki Mori, Keiichi Higuchi, Toshio Takeda, Mitsuru Higuchi, Masashi Tanaka BMC Genomics 2013, 14:248 (15 April 2013)

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Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter

Bridget M Barker, Kristin Kroll, Martin Vödisch, Aurélien Mazurie, Olaf Kniemeyer, Robert A Cramer BMC Genomics 2012, 13:62 (6 February 2012)

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Translational signatures and mRNA levels are highly correlated in human stably expressed genes

Sergio R P Line, Xiaoming Liu, Ana de Souza, Fuli Yu BMC Genomics 2013, 14:268 (19 April 2013)

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Housekeeping and tissue-specific genes in mouse tissues

Kouame E Kouadjo, Yuichiro Nishida, Jean F Cadrin-Girard, Mayumi Yoshioka, Jonny St-Amand BMC Genomics 2007, 8:127 (22 May 2007)

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A hybrid next generation transcript sequencing-based approach to identify allelic and homeolog-specific single nucleotide polymorphisms in allotetraploid white clover

Istvan Nagy, Susanne Barth, Jeanne Mehenni-Ciz, Michael T Abberton, Dan Milbourne BMC Genomics 2013, 14:100 (13 February 2013)

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Optimizing de novo assembly of short-read RNA-seq data for phylogenomics

Ya Yang, Stephen A Smith BMC Genomics 2013, 14:328 (14 May 2013)

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RNA-seq and microarray complement each other in transcriptome profiling

Sunitha Kogenaru, Qing Yan, Yinping Guo, Nian Wang BMC Genomics 2012, 13:629 (15 November 2012)

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Transcriptome-wide comparison of sequence variation in divergent ecotypes of kokanee salmon

Matthew A Lemay, David J Donnelly, Michael A Russello BMC Genomics 2013, 14:308 (7 May 2013)

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Transcriptome-based discovery of pathways and genes related to resistance against Fusarium head blight in wheat landrace Wangshuibai

Jin Xiao, Xiahong Jin, Xinping Jia, Haiyan Wang, Aizhong Cao, Weiping Zhao, Haiyan Pei, Zhaokun Xue, Liqiang He, Qiguang Chen, Xiue Wang BMC Genomics 2013, 14:197 (21 March 2013)

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Comparative transcriptome analysis of Gossypium hirsutum L. in response to sap sucking insects: aphid and whitefly

Neeraj Kumar Dubey, Ridhi Goel, Alok Ranjan, Asif Idris, Sunil Kumar Singh, Sumit K Bag, Krishnappa Chandrashekar, Kapil Deo Pandey, Pradhyumna Kumar Singh, Samir V Sawant BMC Genomics 2013, 14:241 (11 April 2013)

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Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders

Laia Bassaganyas, Eva Riveira-Muñoz, Manel García-Aragonés, Juan R González, Mario Cáceres, Lluís Armengol, Xavier Estivill BMC Genomics 2013, 14:261 (17 April 2013)

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Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

José A Robles, Sumaira E Qureshi, Stuart J Stephen, Susan R Wilson, Conrad J Burden, Jennifer M Taylor BMC Genomics 2012, 13:484 (17 September 2012)

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Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage

Isabelle Rosinski-Chupin, Elisabeth Sauvage, Barbara Mairey, Sophie Mangenot, Laurence Ma, Violette Da Cunha, Christophe Rusniok, Christiane Bouchier, Valérie Barbe, Philippe Glaser BMC Genomics 2013, 14:252 (15 April 2013)

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Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications

Jorge Valdés, Inti Pedroso, Raquel Quatrini, Robert J Dodson, Herve Tettelin, Robert Blake, Jonathan A Eisen, David S Holmes BMC Genomics 2008, 9:597 (11 December 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequence, annotation and bioinformatic analysis extends understanding of the metabolic pathways of the bacterium Acidithiobacillus ferrooxidans including those used during the industrial recovery of copper by bioleaching.

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A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples

Wilbert Zwart, Rutger Koornstra, Jelle Wesseling, Emiel Rutgers, Sabine Linn, Jason S Carroll BMC Genomics 2013, 14:232 (8 April 2013)

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