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1.

9047
Accesses

Research article   Open Access Highly Accessed

Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes

Mari Palgi, Dario Greco, Riitta Lindström, Petri Auvinen, Tapio I Heino BMC Genomics 2012, 13:134 (11 April 2012)

Abstract | Full text | PDF | PubMed

2.

5594
Accesses

Research article   Open Access Highly Accessed

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.

3.

1844
Accesses

Research article   Open Access Highly Accessed

Comparative analysis of fungal genomes reveals different plant cell wall degrading capacity in fungi

Zhongtao Zhao, Huiquan Liu, Chenfang Wang, Jin-Rong Xu BMC Genomics 2013, 14:274 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

1778
Accesses

Research article   Open Access Highly Accessed

Genome analyses of the wheat yellow (stripe) rust pathogen Puccinia striiformis f. sp. tritici reveal polymorphic and haustorial expressed secreted proteins as candidate effectors

Dario Cantu, Vanesa Segovia, Daniel MacLean, Rosemary Bayles, Xianming Chen, Sophien Kamoun, Jorge Dubcovsky, Diane GO Saunders, Cristobal Uauy BMC Genomics 2013, 14:270 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

1765
Accesses

Research article   Open Access Highly Accessed

Gene promoters show chromosome-specificity and reveal chromosome territories in humans

Paul Gagniuc, Constantin Ionescu-Tirgoviste BMC Genomics 2013, 14:278 (24 April 2013)

Abstract | Provisional PDF | PubMed

6.

1613
Accesses

Research article   Open Access Highly Accessed

LEA (Late Embryogenesis Abundant) proteins and their encoding genes in Arabidopsis thaliana

Michaela Hundertmark, Dirk K Hincha BMC Genomics 2008, 9:118 (4 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

1462
Accesses

Methodology article   Open Access Highly Accessed

A data-driven approach to preprocessing Illumina 450K methylation array data

Ruth Pidsley, Chloe C Y Wong, Manuela Volta, Katie Lunnon, Jonathan Mill, Leonard C Schalkwyk BMC Genomics 2013, 14:293 (1 May 2013)

Abstract | Provisional PDF | PubMed

8.

1321
Accesses

Research article   Open Access Highly Accessed

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

Nicolas C Nalpas, Stephen DE Park, David A Magee, Maria Taraktsoglou, John A Browne, Kevin M Conlon, Kévin Rue-Albrecht, Kate E Killick, Karsten Hokamp, Amanda J Lohan, Brendan J Loftus, Eamonn Gormley, Stephen V Gordon, David E MacHugh BMC Genomics 2013, 14:230 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

1309
Accesses

Research article   Open Access Highly Accessed

Strand-specific RNA-seq reveals widespread occurrence of novel cis-natural antisense transcripts in rice

Tingting Lu, Chuanrang Zhu, Guojun Lu, Yunli Guo, Yan Zhou, Zhiyong Zhang, Yan Zhao, Wenjun Li, Ying Lu, Weihua Tang, Qi Feng, Bin Han BMC Genomics 2012, 13:721 (22 December 2012)

Abstract | Full text | PDF | PubMed

10.

1311
Accesses

Software   Open Access Highly Accessed

ContigScape: a Cytoscape plugin facilitating microbial genome gap closing

Biao Tang, Qi Wang, Minjun Yang, Feng Xie, Yongqiang Zhu, Ying Zhuo, Shengyue Wang, Hong Gao, Xiaoming Ding, Lixin Zhang, Guoping Zhao, Huajun Zheng BMC Genomics 2013, 14:289 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

1276
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of differentially expressed genes during anther development in genetic male sterile and wild type cotton by digital gene-expression profiling

Mingming Wei, Meizhen Song, Shuli Fan, Shuxun Yu BMC Genomics 2013, 14:97 (12 February 2013)

Abstract | Full text | PDF | PubMed

12.

1264
Accesses

Research article   Open Access Highly Accessed

Transcriptome analysis of Sacha Inchi (Plukenetia volubilis L.) seeds at two developmental stages

Xiaojuan Wang, Ronghua Xu, Ruling Wang, Aizhong Liu BMC Genomics 2012, 13:716 (20 December 2012)

Abstract | Full text | PDF | PubMed

13.

1242
Accesses

Methodology article   Open Access Highly Accessed

Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes

Petr Dmitriev, Ana Barat, Anna Polesskaya, Mary J O’Connell, Thomas Robert, Philippe Dessen, Thomas A Walsh, Vladimir Lazar, Ahmed Turki, Gilles Carnac, Dalila Laoudj-Chenivesse, Marc Lipinski, Yegor S Vassetzky BMC Genomics 2013, 14:265 (18 April 2013)

Abstract | Full text | PDF | PubMed

14.

1236
Accesses

Research article   Open Access Highly Accessed

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

Colin Clarke, Michael Henry, Padraig Doolan, Shane Kelly, Sinead Aherne, Noelia Sanchez, Paul Kelly, Paula Kinsella, Laura Breen, Stephen F Madden, Lin Zhang, Mark Leonard, Martin Clynes, Paula Meleady, Niall Barron BMC Genomics 2012, 13:656 (21 November 2012)

Abstract | Full text | PDF | PubMed

15.

1180
Accesses

Research article   Open Access

Characterization of human plasma-derived exosomal RNAs by deep sequencing

Xiaoyi Huang, Tiezheng Yuan, Michael Tschannen, Zhifu Sun, Howard Jacob, Meijun Du, Meihua Liang, Rachel L Dittmar, Yong Liu, Mingyu Liang, Manish Kohli, Stephen N Thibodeau, Lisa Boardman, Liang Wang BMC Genomics 2013, 14:319 (10 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

1165
Accesses

Research article   Open Access Highly Accessed

Transcriptomic analysis of ‘Suli’ pear (Pyrus pyrifolia white pear group) buds during the dormancy by RNA-Seq

Guoqin Liu, Wanshun Li, Penghua Zheng, Tong Xu, Lijuan Chen, Dongfeng Liu, Sayed Hussain, Yuanwen Teng BMC Genomics 2012, 13:700 (12 December 2012)

Abstract | Full text | PDF | PubMed

17.

1140
Accesses

Research article   Open Access Highly Accessed

Transcriptomic profiling of the salt-stress response in the wild recretohalophyte Reaumuria trigyna

Zhen-hua Dang, Lin-lin Zheng, Jia Wang, Zhe Gao, Shu-biao Wu, Zhi Qi, Ying-chun Wang BMC Genomics 2013, 14:29 (16 January 2013)

Abstract | Full text | PDF | PubMed

18.

1117
Accesses

Research article   Open Access Highly Accessed

Genome-wide association study of sleep in Drosophila melanogaster

Susan T Harbison, Lenovia J McCoy, Trudy FC Mackay BMC Genomics 2013, 14:281 (25 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

1105
Accesses

Research article   Open Access Highly Accessed

Mapping of pigmentation QTL on an anchored genome assembly of the cichlid fish, Metriaclima zebra

Claire T O¿Quin, Alexi C Drilea, Matthew A Conte, Thomas D Kocher BMC Genomics 2013, 14:287 (27 April 2013)

Abstract | Provisional PDF | PubMed

20.

1097
Accesses

Research article   Open Access Highly Accessed

A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly

Warren R Francis, Lynne M Christianson, Rainer Kiko, Meghan L Powers, Nathan C Shaner, Steven H D Haddock BMC Genomics 2013, 14:167 (12 March 2013)

Abstract | Full text | PDF | PubMed

21.

1092
Accesses

Research article   Open Access Highly Accessed

Genome sequencing of bacteria: sequencing, de novo assembly and rapid analysis using open source tools

Veljo Kisand, Teresa Lettieri BMC Genomics 2013, 14:211 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

22.

1083
Accesses

Expression of concern   Open Access Highly Accessed

Expression of concern: subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances

Maria K Kowalczuk, Shreeya Nanda, Elizabeth C Moylan BMC Genomics 2013, 14:260 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

1075
Accesses

Research article   Open Access

Pause-melting misalignment: a novel model for the birth and motif indel of tandem repeats in the mitochondrial genome

Wei Shi, Xiao-Yu Kong, Zhong-Ming Wang, Shan-Shan Yu, Hai-Xia Chen, Elizabeth A De Stasio BMC Genomics 2013, 14:103 (15 February 2013)

Abstract | Full text | PDF | PubMed

24.

1069
Accesses

Research article   Open Access

A microbial detection array (MDA) for viral and bacterial detection

Shea N Gardner, Crystal J Jaing, Kevin S McLoughlin, Tom R Slezak BMC Genomics 2010, 11:668 (25 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

1079
Accesses

Research article   Open Access

Sequencing platform and library preparation choices impact viral metagenomes

Sergei A Solonenko, J Ignacio-Espinoza, Adriana Alberti, Corinne Cruaud, Steven Hallam, Kostas Konstantinidis, Gene Tyson, Patrick Wincker, Matthew B Sullivan BMC Genomics 2013, 14:320 (10 May 2013)

Abstract | Full text | PDF | PubMed

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