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1.

6417
Accesses

Research article   Open Access Highly Accessed

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.

2.

3986
Accesses

Research article   Open Access Highly Accessed

Draft genome sequence of the rubber tree Hevea brasiliensis

Ahmad Yamin Abdul Rahman, Abhilash O Usharraj, Biswapriya B Misra, Gincy P Thottathil, Kandakumar Jayasekaran, Yun Feng, Shaobin Hou, Su Yean Ong, Fui Ling Ng, Ling Sze Lee, Hock Siew Tan, Muhd Khairul Luqman Muhd Sakaff, Beng Soon Teh, Bee Khoo, Siti Suriawati Badai, Nurohaida Ab Aziz, Anton Yuryev, Bjarne Knudsen, Alexandre Dionne-Laporte, Nokuthula P Mchunu, Qingyi Yu, Brennick J Langston, Tracey Allen K Freitas, Aaron G Young, Rui Chen, Lei Wang, Nazalan Najimudin, Jennifer A Saito, Maqsudul Alam BMC Genomics 2013, 14:75 (2 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The draft genome of the rubber tree Hevea brasiliensis is almost 80% repetitive DNA with 12.7% of genes models identified being unique to this species, including key rubber biosynthesis and disease resistance genes

3.

3417
Accesses

Research article   Open Access Highly Accessed

Insights into the evolution of Darwin’s finches from comparative analysis of the Geospiza magnirostris genome sequence

Chris M Rands, Aaron Darling, Matthew Fujita, Lesheng Kong, Matthew T Webster, Céline Clabaut, Richard D Emes, Andreas Heger, Stephen Meader, Michael Brent Hawkins, Michael B Eisen, Clotilde Teiling, Jason Affourtit, Benjamin Boese, Peter R Grant, Barbara Rosemary Grant, Jonathan A Eisen, Arhat Abzhanov, Chris P Ponting BMC Genomics 2013, 14:95 (12 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

204 years after Charles Darwin’s birth, sequencing of the genome of the Darwin’s Finch Geospiza magnirostris reveals over 13,000 predicted genes, of which two under positive selection may have contributed to beak morphology evolution, which so interested Darwin.

4.

2568
Accesses

Research article   Open Access Highly Accessed

Genome-wide identification, characterization, and expression analysis of lineage-specific genes within zebrafish

Liandong Yang, Ming Zou, Beide Fu, Shunping He BMC Genomics 2013, 14:65 (31 January 2013)

Abstract | Provisional PDF | PubMed

5.

2537
Accesses

Methodology article   Open Access Highly Accessed

Genotyping 1000 yeast strains by next-generation sequencing

Stefan Wilkening, Manu M Tekkedil, Gen Lin, Emilie S Fritsch, Wu Wei, Julien Gagneur, David W Lazinski, Andrew Camilli, Lars M Steinmetz BMC Genomics 2013, 14:90 (9 February 2013)

Abstract | Full text | PDF | PubMed

6.

2142
Accesses

Research article   Open Access Highly Accessed

Comparative genomic analyses of Mycoplasma hyopneumoniae pathogenic 168 strain and its high-passaged attenuated strain

Wei Liu, Shaobo Xiao, Mao Li, Shaohua Guo, Sha Li, Rui Luo, Zhixin Feng, Bin Li, Zhemin Zhou, Guoqing Shao, Huanchun Chen, Liurong Fang BMC Genomics 2013, 14:80 (5 February 2013)

Abstract | Provisional PDF | PubMed

7.

2124
Accesses

Research article   Open Access Highly Accessed

An R2R3 MYB transcription factor determines red petal colour in an Actinidia (kiwifruit) hybrid population

Lena G Fraser, Alan G Seal, Mirco Montefiori, Tony K McGhie, Gianna K Tsang, Paul M Datson, Elena Hilario, Hinga E Marsh, Juanita K Dunn, Roger P Hellens, Kevin M Davies, Mark A McNeilage, H Nihal Silva, Andrew C Allan BMC Genomics 2013, 14:28 (16 January 2013)

Abstract | Provisional PDF | PubMed

8.

2056
Accesses

Research article   Open Access Highly Accessed

Transcriptome analysis of rice root heterosis by RNA-Seq

Rongrong Zhai, Yue Feng, Huimin Wang, Xiaodeng Zhan, Xihong Shen, Weiming Wu, Yingxin Zhang, Daibo Chen, Gaoxing Dai, Zhanlie Yang, Liyong Cao, Shihua Cheng BMC Genomics 2013, 14:19 (16 January 2013)

Abstract | Full text | PDF | PubMed

9.

1931
Accesses

Research article   Open Access Highly Accessed

Genome-wide analysis of histone modifiers in tomato: gaining an insight into their developmental roles

Riccardo Aiese Cigliano, Walter Sanseverino, Gaetana Cremona, Maria R Ercolano, Clara Conicella, Federica M Consiglio BMC Genomics 2013, 14:57 (28 January 2013)

Abstract | Full text | PDF | PubMed

10.

1815
Accesses

Research article   Open Access Highly Accessed

Eukaryotic genomes may exhibit up to 10 generic classes of gene promoters

Paul Gagniuc, Constantin Ionescu-Tirgoviste BMC Genomics 2012, 13:512 (28 September 2012)

Abstract | Full text | PDF | PubMed

11.

1814
Accesses

Research article   Open Access Highly Accessed

LEA (Late Embryogenesis Abundant) proteins and their encoding genes in Arabidopsis thaliana

Michaela Hundertmark, Dirk K Hincha BMC Genomics 2008, 9:118 (4 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

1791
Accesses

Research article   Open Access Highly Accessed

Comparison of metagenomic samples using sequence signatures

Bai Jiang, Kai Song, Jie Ren, Minghua Deng, Fengzhu Sun, Xuegong Zhang BMC Genomics 2012, 13:730 (27 December 2012)

Abstract | Full text | PDF | PubMed

13.

1690
Accesses

Research article   Open Access Highly Accessed

Transcriptome of the dead: characterisation of immune genes and marker development from necropsy samples in a free-ranging marine mammal

Joseph I Hoffman, Michael AS Thorne, Philip N Trathan, Jaume Forcada BMC Genomics 2013, 14:52 (24 January 2013)

Abstract | Full text | PDF | PubMed

14.

1669
Accesses

Research article   Open Access Highly Accessed

Genome sequence reveals that Pseudomonas fluorescens F113 possesses a large and diverse array of systems for rhizosphere function and host interaction

Miguel Redondo-Nieto, Matthieu Barret, John Morrissey, Kieran Germaine, Francisco Martínez-Granero, Emma Barahona, Ana Navazo, María Sánchez-Contreras, Jennifer A Moynihan, Candela Muriel, David Dowling, Fergal O’Gara, Marta Martín, Rafael Rivilla BMC Genomics 2013, 14:54 (25 January 2013)

Abstract | Full text | PDF | PubMed

15.

1635
Accesses

Research article   Open Access Highly Accessed

Identification and characterization of microRNAs in Phaseolus vulgaris by high-throughput sequencing

Pablo Peláez, Minerva S Trejo, Luis P Iñiguez, Georgina Estrada-Navarrete, Alejandra A Covarrubias, José L Reyes, Federico Sanchez BMC Genomics 2012, 13:83 (6 March 2012)

Abstract | Full text | PDF | PubMed

16.

1631
Accesses

Research article   Open Access Highly Accessed

Combining proteomics and transcriptome sequencing to identify active plant-cell-wall-degrading enzymes in a leaf beetle

Roy Kirsch, Natalie Wielsch, Heiko Vogel, Aleš Svatoš, David G Heckel, Yannick Pauchet BMC Genomics 2012, 13:587 (1 November 2012)

Abstract | Full text | PDF | PubMed

17.

1633
Accesses

Research article   Open Access Highly Accessed

Transcriptomic profiling of the salt-stress response in the wild recretohalophyte Reaumuria trigyna

Zhen-hua Dang, Lin-lin Zheng, Jia Wang, Zhe Gao, Shu-biao Wu, Zhi Qi, Ying-chun Wang BMC Genomics 2013, 14:29 (16 January 2013)

Abstract | Full text | PDF | PubMed

18.

1628
Accesses

Research article   Open Access Highly Accessed

Small RNA pyrosequencing in the protozoan parasite Entamoeba histolytica reveals strain-specific small RNAs that target virulence genes

Hanbang Zhang, Gretchen M Ehrenkaufer, Neil Hall, Upinder Singh BMC Genomics 2013, 14:53 (25 January 2013)

Abstract | Provisional PDF | PubMed

19.

1592
Accesses

Research article   Open Access Highly Accessed

Powdery mildew fungal effector candidates share N-terminal Y/F/WxC-motif

Dale Godfrey, Henrik Böhlenius, Carsten Pedersen, Ziguo Zhang, Jeppe Emmersen, Hans Thordal-Christensen BMC Genomics 2010, 11:317 (20 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

20.

1579
Accesses

Research article   Open Access Highly Accessed

Whole transcriptome analysis of the silicon response of the diatom Thalassiosira pseudonana

Roshan Shrestha, Benoit Tesson, Trina Norden-Krichmar, Stephen Federowicz, Mark Hildebrand, Andrew E Allen BMC Genomics 2012, 13:499 (20 September 2012)

Abstract | Full text | PDF | PubMed

21.

1570
Accesses

Methodology article   Open Access Highly Accessed

Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing

Junwen Wang, Yudong Xia, Lili Li, Desheng Gong, Yu Yao, Huijuan Luo, Hanlin Lu, Na Yi, Honglong Wu, Xiuqing Zhang, Qian Tao, Fei Gao BMC Genomics 2013, 14:11 (16 January 2013)

Abstract | Full text | PDF | PubMed

22.

1563
Accesses

Research article   Open Access Highly Accessed

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Combiz Khozoie, Michael G Borland, Bokai Zhu, Songjoon Baek, Sam John, Gordon L Hager, Yatrik M Shah, Frank J Gonzalez, Jeffrey M Peters BMC Genomics 2012, 13:665 (24 November 2012)

Abstract | Full text | PDF | PubMed

23.

1538
Accesses

Research article   Open Access Highly Accessed

Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018

Shiyuan Hu, Huajun Zheng, Yang Gu, Jingbo Zhao, Weiwen Zhang, Yunliu Yang, Shengyue Wang, Guoping Zhao, Sheng Yang, Weihong Jiang BMC Genomics 2011, 12:93 (2 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

1526
Accesses

Research article   Open Access Highly Accessed

De novo sequencing and analysis of root transcriptome using 454 pyrosequencing to discover putative genes associated with drought tolerance in Ammopiptanthus mongolicus

Yijun Zhou, Fei Gao, Ran Liu, Jinchao Feng, Hongjie Li BMC Genomics 2012, 13:266 (21 June 2012)

Abstract | Full text | PDF | PubMed

25.

1527
Accesses

Research article   Open Access Highly Accessed

Centering, scaling, and transformations: improving the biological information content of metabolomics data

Robert A van den Berg, Huub CJ Hoefsloot, Johan A Westerhuis, Age K Smilde, Mariët J van der Werf BMC Genomics 2006, 7:142 (8 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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