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1.

Research article   Open Access Highly Accessed

Mobile phone radiation might alter protein expression in human skin

Anu Karinen, Sirpa Heinävaara, Reetta Nylund, Dariusz Leszczynski BMC Genomics 2008, 9:77 (11 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 5 comments |  Editor’s summary

Mobile phone radiation affected the expression level of certain proteins in the skin of 10 human volunteers as measured by proteomic techniques, tentative support for earlier in vitro results.

2.

Methodology article   Open Access Highly Accessed

Comparison of next generation sequencing technologies for transcriptome characterization

P Kerr Wall, Jim Leebens-Mack, André S Chanderbali, Abdelali Barakat, Erik Wolcott, Haiying Liang, Lena Landherr, Lynn P Tomsho, Yi Hu, John E Carlson, Hong Ma, Stephan C Schuster, Douglas E Soltis, Pamela S Soltis, Naomi Altman, Claude W dePamphilis BMC Genomics 2009, 10:347 (1 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

Correspondence   Open Access Highly Accessed

Addressing challenges in the production and analysis of illumina sequencing data

Martin Kircher, Patricia Heyn, Janet Kelso BMC Genomics 2011, 12:382 (29 July 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Janet Kelso and colleagues review the potential problems and suggested solutions for users of Illumina sequencers, including general principles for library preparation, image analysis, run parameters and handling of sequences containing adapter chimeras.

4.

Research article   Open Access Highly Accessed

Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers

Xinxia Peng, Yu Li, Kathie-Anne Walters, Elizabeth R Rosenzweig, Sharon L Lederer, Lauri D Aicher, Sean Proll, Michael G Katze BMC Genomics 2009, 10:373 (11 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

Research article   Open Access Highly Accessed

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.

6.

Research article   Open Access Highly Accessed

Sugarcane genes associated with sucrose content

Flávia S Papini-Terzi, Flávia R Rocha, Ricardo ZN Vêncio, Juliana M Felix, Diana S Branco, Alessandro J Waclawovsky, Luiz EV Del Bem, Carolina G Lembke, Maximiller DL Costa, Milton Y Nishiyama, Renato Vicentini, Michel GA Vincentz, Eugênio C Ulian, Marcelo Menossi, Glaucia M Souza BMC Genomics 2009, 10:120 (21 March 2009)

Abstract | Full text | PDF | PubMed

7.

Methodology article   Open Access Highly Accessed

Viral genome sequencing by random priming methods

Appolinaire Djikeng, Rebecca Halpin, Ryan Kuzmickas, Jay DePasse, Jeremy Feldblyum, Naomi Sengamalay, Claudio Afonso, Xinsheng Zhang, Norman G Anderson, Elodie Ghedin, David J Spiro BMC Genomics 2008, 9:5 (7 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

Research article   Open Access Highly Accessed

Horizontal transfer of expressed genes in a parasitic flowering plant

Zhenxiang Xi, Robert K Bradley, Kenneth J Wurdack, KM Wong, M Sugumaran, Kirsten Bomblies, Joshua S Rest, Charles C Davis BMC Genomics 2012, 13:227 (8 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Charles Davis and colleagues provide first evidence of horizontal gene transfer from host to the parasitic flowering plant, Rafflesia cantleyi, on an unprecedented scale raising the possibility that there is a 'fitness' benefit to the parasite.

9.

Research article   Open Access Highly Accessed

Sequencing and de novo analysis of a coral larval transcriptome using 454 GSFlx

Eli Meyer, Galina V Aglyamova, Shi Wang, Jade Buchanan-Carter, David Abrego, John K Colbourne, Bette L Willis, Mikhail V Matz BMC Genomics 2009, 10:219 (12 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Rapid sequencing of the transcribed genes of coral larvae is made possible by the use of adapted next-generation sequencing methods, revealing around 11,000 expressed genes and candidate genes for the response to temperature stress.

10.

Research article   Open Access Highly Accessed

Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications

Jorge Valdés, Inti Pedroso, Raquel Quatrini, Robert J Dodson, Herve Tettelin, Robert Blake, Jonathan A Eisen, David S Holmes BMC Genomics 2008, 9:597 (11 December 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sequence, annotation and bioinformatic analysis extends understanding of the metabolic pathways of the bacterium Acidithiobacillus ferrooxidans including those used during the industrial recovery of copper by bioleaching.

11.

Research article   Open Access Highly Accessed

Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs

Steffen G Jensen, Philippe Lamy, Mads H Rasmussen, Marie S Ostenfeld, Lars Dyrskjøt, Torben F Ørntoft, Claus L Andersen BMC Genomics 2011, 12:435 (26 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

Software   Open Access Highly Accessed

BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons

Nabil-Fareed Alikhan, Nicola K Petty, Nouri L Ben Zakour, Scott A Beatson BMC Genomics 2011, 12:402 (8 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The BLAST Ring Image Generator (BRIG) software allows users to rapidly visualize comparisons between large numbers of bacterial genomes, including unfinished or unassembled genome data, in a single image.

13.

Research article   Open Access Highly Accessed

Matching curated genome databases: a non trivial task

Stéphane Descorps-Declère, Matthieu Barba, Bernard Labedan BMC Genomics 2008, 9:501 (24 October 2008)

Abstract | Full text | PDF | PubMed

14.

Methodology article   Open Access Highly Accessed

RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization

Tomas Hruz, Markus Wyss, Mylene Docquier, Michael W Pfaffl, Sabine Masanetz, Lorenzo Borghi, Phebe Verbrugghe, Luba Kalaydjieva, Stefan Bleuler, Oliver Laule, Patrick Descombes, Wilhelm Gruissem, Philip Zimmermann BMC Genomics 2011, 12:156 (21 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

15.

Research article   Open Access Highly Accessed

Protein abundance profiling of the Escherichia coli cytosol

Yasushi Ishihama, Thorsten Schmidt, Juri Rappsilber, Matthias Mann, F Ulrich Hartl, Michael J Kerner, Dmitrij Frishman BMC Genomics 2008, 9:102 (27 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

16.

Research article   Open Access Highly Accessed

Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays

Joshua S Bloom, Zia Khan, Leonid Kruglyak, Mona Singh, Amy A Caudy BMC Genomics 2009, 10:221 (12 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

17.

Methodology article   Open Access Highly Accessed

Genome-wide transcription factor binding site/promoter databases for the analysis of gene sets and co-occurrence of transcription factor binding motifs

Srinivas Veerla, Markus Ringnér, Mattias Höglund BMC Genomics 2010, 11:145 (1 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

Research article   Open Access Highly Accessed

Characterization of microRNA expression profiles in normal human tissues

Yu Liang, Dana Ridzon, Linda Wong, Caifu Chen BMC Genomics 2007, 8:166 (12 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

Methodology article   Open Access Highly Accessed

Estimating accuracy of RNA-Seq and microarrays with proteomics

Xing Fu, Ning Fu, Song Guo, Zheng Yan, Ying Xu, Hao Hu, Corinna Menzel, Wei Chen, Yixue Li, Rong Zeng, Philipp Khaitovich BMC Genomics 2009, 10:161 (16 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

Research article   Open Access Highly Accessed

Comparing de novo assemblers for 454 transcriptome data

Sujai Kumar, Mark L Blaxter BMC Genomics 2010, 11:571 (16 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

21.

Database   Open Access Highly Accessed

PlantPAN: Plant promoter analysis navigator, for identifying combinatorial cis-regulatory elements with distance constraint in plant gene groups

Wen-Chi Chang, Tzong-Yi Lee, Hsien-Da Huang, His-Yuan Huang, Rong-Long Pan BMC Genomics 2008, 9:561 (26 November 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

Research article   Open Access Highly Accessed

Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay

Laurent G Deluc, David R Quilici, Alain Decendit, Jérôme Grimplet, Matthew D Wheatley, Karen A Schlauch, Jean-Michel Mérillon, John C Cushman, Grant R Cramer BMC Genomics 2009, 10:212 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

Research article   Open Access Highly Accessed

The adaptive evolution of the mammalian mitochondrial genome

Rute R da Fonseca, Warren E Johnson, Stephen J O'Brien, Maria Ramos, Agostinho Antunes BMC Genomics 2008, 9:119 (4 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Methodology article   Open Access Highly Accessed

Digital PCR provides sensitive and absolute calibration for high throughput sequencing

Richard A White, Paul C Blainey, H Christina Fan, Stephen R Quake BMC Genomics 2009, 10:116 (19 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Research article   Open Access Highly Accessed

What can you do with 0.1× genome coverage? A case study based on a genome survey of the scuttle fly Megaselia scalaris (Phoridae)

David A Rasmussen, Mohamed AF Noor BMC Genomics 2009, 10:382 (18 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Random pyrosequencing of approximately 10% of the scuttle fly genome yielded novel repetitive elements, a near-complete mitochondrial genome sequence and microsatellite markers, showing that inexpensive low-coverage screens can provide useful data on non-model organisms.

26.

Research article   Open Access Highly Accessed

A universal DNA mini-barcode for biodiversity analysis

Isabelle Meusnier, Gregory AC Singer, Jean-François Landry, Donal A Hickey, Paul DN Hebert, Mehrdad Hajibabaei BMC Genomics 2008, 9:214 (12 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

Proceedings   Open Access Highly Accessed

The value of avian genomics to the conservation of wildlife

Michael N Romanov, Elaina M Tuttle, Marlys L Houck, William S Modi, Leona G Chemnick, Marisa L Korody, Emily Mork, Christie A Otten, Tanya Renner, Kenneth C Jones, Sugandha Dandekar, Jeanette C Papp, Yang Da, NISC Comparative Sequencing Program, Eric D Green, Vincent Magrini, Matthew T Hickenbotham, Jarret Glasscock, Sean McGrath, Elaine R Mardis, Oliver A Ryder BMC Genomics 2009, 10(Suppl 2):S10 (14 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

Research article   Open Access Highly Accessed

Transcriptome sequencing in an ecologically important tree species: assembly, annotation, and marker discovery

Thomas L Parchman, Katherine S Geist, Johan A Grahnen, Craig W Benkman, C Alex Buerkle BMC Genomics 2010, 11:180 (16 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

Research article   Open Access Highly Accessed

Transcriptome analysis of the venom gland of the scorpion Scorpiops jendeki: implication for the evolution of the scorpion venom arsenal

Yibao Ma, Ruiming Zhao, Yawen He, Songryong Li, Jun Liu, Yingliang Wu, Zhijian Cao, Wenxin Li BMC Genomics 2009, 10:290 (1 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A transcriptome analysis of the Scorpiops jendeki venom gland has highlighted a number of venom peptides which may help drug development and aid our understanding of how the scorpion evolved its venom arsenal.

30.

Research article   Open Access Highly Accessed

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

Alessandro Guffanti, Michele Iacono, Paride Pelucchi, Namshin Kim, Giulia Soldà, Larry J Croft, Ryan J Taft, Ermanno Rizzi, Marjan Askarian-Amiri, Raoul J Bonnal, Maurizio Callari, Flavio Mignone, Graziano Pesole, Giovanni Bertalot, Luigi Bernardi, Alberto Albertini, Christopher Lee, John S Mattick, Ileana Zucchi, Gianluca De Bellis BMC Genomics 2009, 10:163 (20 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

Research article   Open Access

Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome

Alexandra M Lopes, Paul S Burgoyne, Andrew Ojarikre, Julien Bauer, Carole A Sargent, António Amorim, Nabeel A Affara BMC Genomics 2010, 11:82 (1 February 2010)

Abstract | Full text | PDF | PubMed

32.

Research article   Open Access Highly Accessed

Genome-wide search reveals a novel GacA-regulated small RNA in Pseudomonas species

Nicolas González, Stephan Heeb, Claudio Valverde, Elisabeth Kay, Cornelia Reimmann, Thomas Junier, Dieter Haas BMC Genomics 2008, 9:167 (13 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

Research article   Open Access Highly Accessed

Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation

Sergei A Manakov, Seth GN Grant, Anton J Enright BMC Genomics 2009, 10:419 (8 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

Research article   Open Access Highly Accessed

Comparative mapping of Brassica juncea and Arabidopsis thaliana using Intron Polymorphism (IP) markers: homoeologous relationships, diversification and evolution of the A, B and C Brassica genomes

Priya Panjabi, Arun Jagannath, Naveen C Bisht, K Lakshmi Padmaja, Sarita Sharma, Vibha Gupta, Akshay K Pradhan, Deepak Pental BMC Genomics 2008, 9:113 (3 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

Research article   Open Access Highly Accessed

Identification of plant promoter constituents by analysis of local distribution of short sequences

Yoshiharu Y Yamamoto, Hiroyuki Ichida, Minami Matsui, Junichi Obokata, Tetsuya Sakurai, Masakazu Satou, Motoaki Seki, Kazuo Shinozaki, Tomoko Abe BMC Genomics 2007, 8:67 (8 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

36.

Research article   Open Access Highly Accessed

Gene expression during Drosophila melanogaster egg development before and after reproductive diapause

Dean A Baker, Steven Russell BMC Genomics 2009, 10:242 (24 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

Methodology article   Open Access Highly Accessed

Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing

Philippe Lefrançois, Ghia M Euskirchen, Raymond K Auerbach, Joel Rozowsky, Theodore Gibson, Christopher M Yellman, Mark Gerstein, Michael Snyder BMC Genomics 2009, 10:37 (21 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

Methodology article   Open Access Highly Accessed

Gene Expression and Isoform Variation Analysis using Affymetrix Exon Arrays

Amandine Bemmo, David Benovoy, Tony Kwan, Daniel J Gaffney, Roderick V Jensen, Jacek Majewski BMC Genomics 2008, 9:529 (7 November 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

Research article   Open Access Highly Accessed

Low-pass shotgun sequencing of the barley genome facilitates rapid identification of genes, conserved non-coding sequences and novel repeats

Thomas Wicker, Apurva Narechania, Francois Sabot, Joshua Stein, Giang TH Vu, Andreas Graner, Doreen Ware, Nils Stein BMC Genomics 2008, 9:518 (31 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

40.

Research article   Open Access Highly Accessed

Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

José A Robles, Sumaira E Qureshi, Stuart J Stephen, Susan R Wilson, Conrad J Burden, Jennifer M Taylor BMC Genomics 2012, 13:484 (17 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

41.

Research article   Open Access Highly Accessed

Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction

Kun-Chieh Cheng, Hsuan-Cheng Huang, Jenn-Han Chen, Jia-Wei Hsu, Hsu-Chieh Cheng, Chern-Han Ou, Wen-Bin Yang, Shui-Tein Chen, Chi-Huey Wong, Hsueh-Fen Juan BMC Genomics 2007, 8:411 (9 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

Research article   Open Access Highly Accessed

Hidden layers of human small RNAs

Hideya Kawaji, Mari Nakamura, Yukari Takahashi, Albin Sandelin, Shintaro Katayama, Shiro Fukuda, Carsten O Daub, Chikatoshi Kai, Jun Kawai, Jun Yasuda, Piero Carninci, Yoshihide Hayashizaki BMC Genomics 2008, 9:157 (10 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Unbiased sequencing of 19 to 40 nucleotide-long RNAs in human cells suggests the existence of small RNAs originating from longer, more well-characterized non-coding RNAs, such as tRNAs, and also reveals six previously unknown miRNAs.

43.

Research article   Open Access

Sessile snails, dynamic genomes: gene rearrangements within the mitochondrial genome of a family of caenogastropod molluscs

Timothy A Rawlings, Martin J MacInnis, Rüdiger Bieler, Jeffrey L Boore, Timothy M Collins BMC Genomics 2010, 11:440 (19 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

44.

Research article   Open Access Highly Accessed

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

Robert Pinard, Alex de Winter, Gary J Sarkis, Mark B Gerstein, Karrie R Tartaro, Ramona N Plant, Michael Egholm, Jonathan M Rothberg, John H Leamon BMC Genomics 2006, 7:216 (23 August 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

45.

Research article   Open Access Highly Accessed

Horizontal gene transfer between Wolbachia and the mosquito Aedes aegypti

Lisa Klasson, Zakaria Kambris, Peter E Cook, Thomas Walker, Steven P Sinkins BMC Genomics 2009, 10:33 (20 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

46.

Research article   Open Access Highly Accessed

Comparison of frozen and RNALater solid tissue storage methods for use in RNA expression microarrays

George L Mutter, David Zahrieh, Chunmei Liu, Donna Neuberg, David Finkelstein, Heather E Baker, Janet A Warrington BMC Genomics 2004, 5:88 (10 November 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

47.

Software   Open Access Highly Accessed

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

Tim Hulsen, Jacob de Vlieg, Wynand Alkema BMC Genomics 2008, 9:488 (16 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

Database   Open Access

ArachnoServer: a database of protein toxins from spiders

David LA Wood, Tomas Miljenović, Shuzhi Cai, Robert J Raven, Quentin Kaas, Pierre Escoubas, Volker Herzig, David Wilson, Glenn F King BMC Genomics 2009, 10:375 (13 August 2009)

Abstract | Full text | PDF | PubMed

49.

Research article   Open Access Highly Accessed

Comparative genomics of Toll-like receptor signalling in five species

Oliver C Jann, Annemarie King, Nestor Corrales, Susan I Anderson, Kirsty Jensen, Tahar Ait-ali, Haizhou Tang, Chunhua Wu, Noelle E Cockett, Alan L Archibald, Elizabeth J Glass BMC Genomics 2009, 10:216 (11 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Toll-like receptors (TLRs) form part of the immune arsenal of mammals and mapping of TLR loci in sheep and pigs reveals genes for resistance to particular infections that appear conserved across several mammalian species.

50.

Research article   Open Access Highly Accessed

The Odorant Binding Protein Gene Family from the Genome of Silkworm, Bombyx mori

Da-Ping Gong, Hui-Jie Zhang, Ping Zhao, Qing-You Xia, Zhong-Huai Xiang BMC Genomics 2009, 10:332 (23 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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