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- Inge Depoortere, Catholic University Leuven
- Arthur Kaser, University of Cambridge
- Rakesh Tandon, Pushpawati Singhania Research Institute
- Christian Trautwein, Universitätsklinikum Aachen
- David Watson, Flinders University
- Joanne Young, Queensland Institute of Medical Research
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BMC Gastroenterology 2012, 12:41Oral arginine reduces intestinal injury
In a rat model, dietary L-Arginine supplementation prevents mucosal injury, decreases cell death via apoptosis and improves intestinal recovery following methotrexate (MTX)-induced intestinal injury, suggesting that oral arginine may have clinical value for the treatment of chemotherapy-induced mucositis.
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BMC Gastroenterology 2012, 12:9Luteolin reduces IGF-IR signalling
Luteolin, a flavonoid found in fruits and vegetables, reduces insulin-like growth factor-I receptor (IGF-IR) signaling in colon cancer cells, suggesting that this mechanism may contribute to luteolin-induced apoptosis and cell cycle arrest.
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BMC Gastroenterology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of gastrointestinal and hepatobiliary disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.
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