Volume 2 (2002) - October 2002
J Arjan GM de Visser, Richard E Lenski BMC Evolutionary Biology 2002, 2:19 (30 October 2002)
Early incorporation of the major mutations that provide the greatest gains in fitness accounts for the deceleration in the rate of fitness improvement observed during experimental evolution of E. coli over 20,000 generations.
Georgy P Karev, Yuri I Wolf, Andrey Y Rzhetsky, Faina S Berezovskaya, Eugene V Koonin BMC Evolutionary Biology 2002, 2:18 (14 October 2002)
A simple model of evolution of the domain composition of proteins which includes domain birth, death and innovation, but not explicitly selection, can explain the observed power law distribution of domain family size.