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Regeneration and repair Section edited by Enrique Amaya

This section considers studies in the regeneration and repair of organisms and tissues.

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1.

Research article   Open Access

Human amniotic fluid stem cells have a potential to recover ovarian function in mice with chemotherapy-induced sterility

Dongmei Lai, Fangyuan Wang, Yifei Chen, Li Wang, Yanlin Wang, Weiwei Cheng BMC Developmental Biology 2013, 13:34 (4 September 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Human amniotic fluid stem cells (hAFCs), injected into the ovaries of sterile mice, have the ability to restore ovarian morphology, indicating the potential of these cells for reproductive regenerative medicine.

2.

Methodology article   Open Access

Foamy virus for efficient gene transfer in regeneration studies

Shahryar Khattak, Tatiana Sandoval-Guzmán, Nicole Stanke, Stephanie Protze, Elly M Tanaka, Dirk Lindemann BMC Developmental Biology 2013, 13:17 (3 May 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Replication-deficient foamy virus vectors are an efficient means of transferring genes into axolotl limb and tail cells, with infection persisting throughout regeneration and re-amputation allowing tests of gene function in this experimental model.

3.

Methodology article   Open Access Highly Accessed

In situ hybridization protocol for enhanced detection of gene expression in the planarian Schmidtea mediterranea

Ryan S King, Phillip A Newmark BMC Developmental Biology 2013, 13:8 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Modification of multiple steps in in situ hybridization methods for the freshwater planarian Schmidtea mediterranea greatly increase signal detection and may prove useful for whole-mount fluorescent in situ hybridization (FISH) in other model organisms

4.

Research article   Open Access

Cell proliferation is necessary for the regeneration of oral structures in the anthozoan cnidarian Nematostella vectensis

Yale J Passamaneck, Mark Q Martindale BMC Developmental Biology 2012, 12:34 (4 December 2012)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access Highly Accessed

An amputation resets positional information to a proximal identity in the regenerating zebrafish caudal fin

Ana Azevedo, Sara Sousa, António Jacinto, Leonor Saúde BMC Developmental Biology 2012, 12:24 (25 August 2012)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access Highly Accessed

Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae

Alexandre Rodrigues, Bea Christen, Mercé Martí, Juan Carlos Izpisúa Belmonte BMC Developmental Biology 2012, 12:9 (27 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | f1000 |  Editor’s summary

Regenerating limbs in lower amphibians, such as tadpoles and zebrafish, show no evidence of myofibre dedifferentiation indicating that this process is less important to regeneration than previously thought and implicating progenitor cells as the major players.

7.

Research article   Open Access Highly Accessed

Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration

Nick R Love, Yaoyao Chen, Boyan Bonev, Michael J Gilchrist, Lynne Fairclough, Robert Lea, Timothy J Mohun, Roberto Paredes, Leo AH Zeef, Enrique Amaya BMC Developmental Biology 2011, 11:70 (15 November 2011)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea

Tracy Chong, Joel M Stary, Yuying Wang, Phillip A Newmark BMC Developmental Biology 2011, 11:69 (10 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

Research article   Open Access

Cell dedifferentiation and epithelial to mesenchymal transitions during intestinal regeneration in H. glaberrima

José E García-Arrarás, Griselle Valentín-Tirado, Jaime E Flores, Rey J Rosa, Angélica Rivera-Cruz, José E San Miguel-Ruiz, Karen Tossas BMC Developmental Biology 2011, 11:61 (17 October 2011)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access Highly Accessed

A novel amniote model of epimorphic regeneration: the leopard gecko, Eublepharis macularius

Katherine E McLean, Matthew K Vickaryous BMC Developmental Biology 2011, 11:50 (16 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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