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1.

1527
Accesses

Research article   Open Access Highly Accessed

Sex and the single embryo: early deveopment in the Mediterranean fruit fly, Ceratitis capitata

Paolo Gabrieli, Andrea Falaguerra, Paolo Siciliano, Ludvik M Gomulski, Francesca Scolari, Antigone Zacharopoulou, Gerald Franz, Anna R Malacrida, Giuliano Gasperi BMC Developmental Biology 2010, 10:12 (26 January 2010)

Abstract | Full text | PDF | PubMed

2.

1363
Accesses

Research article   Open Access Highly Accessed

Characterization of the stem cell system of the acoel Isodiametra pulchra

Katrien De Mulder, Georg Kuales, Daniela Pfister, Maxime Willems, Bernhard Egger, Willi Salvenmoser, Marlene Thaler, Anne-Kathrin Gorny, Martina Hrouda, Gaëtan Borgonie, Peter Ladurner BMC Developmental Biology 2009, 9:69 (18 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The acoel Isodiametra pulchra has neoblasts that are potent stem cells crucial for tissue homeostasis, development and regeneration, and is a new model organism for studying development in this primitive bilaterian phylum.

3.

1276
Accesses

Research article   Open Access Highly Accessed

Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1

Anne-Christine Hick, Jonathan M van Eyll, Sabine Cordi, Céline Forez, Lara Passante, Hiroshi Kohara, Takashi Nagasawa, Pierre Vanderhaeghen, Pierre J Courtoy, Guy G Rousseau, Frédéric P Lemaigre, Christophe E Pierreux BMC Developmental Biology 2009, 9:66 (14 December 2009)

Abstract | Full text | PDF | PubMed

4.

1133
Accesses

Research article   Open Access Highly Accessed

Standardised classification of pre-release development in male-brooding pipefish, seahorses, and seadragons (Family Syngnathidae)

Stefan Sommer, Camilla M Whittington, Anthony B Wilson BMC Developmental Biology 2012, 12:39 (29 December 2012)

Abstract | Full text | PDF | PubMed

5.

680
Accesses

Research article   Open Access

Human amniotic fluid stem cells have a potential to recover ovarian function in mice with chemotherapy-induced sterility

Dongmei Lai, Fangyuan Wang, Yifei Chen, Li Wang, Yanlin Wang, Weiwei Cheng BMC Developmental Biology 2013, 13:34 (4 September 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Human amniotic fluid stem cells (hAFCs), injected into the ovaries of sterile mice, have the ability to restore ovarian morphology, indicating the potential of these cells for reproductive regenerative medicine.

6.

646
Accesses

Research article   Open Access

The gene transformer-2 of Sciara (Diptera, Nematocera) and its effect on Drosophila sexual development

Iker Martín, María F Ruiz, Lucas Sánchez BMC Developmental Biology 2011, 11:19 (15 March 2011)

Abstract | Full text | PDF | PubMed

7.

616
Accesses

Methodology article   Open Access Highly Accessed

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Shankar Srinivas, Tomoko Watanabe, Chyuan-Sheng Lin, Chris M William, Yasuto Tanabe, Thomas M Jessell, Frank Costantini BMC Developmental Biology 2001, 1:4 (27 March 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Two new reporter lines of mice enable Cre expression to be monitored in living tissues. This provides a valuable tool to trace cell lineage and simultaneously monitor gene expression in the developing embryo.

8.

516
Accesses

Research article   Open Access Highly Accessed

Molecular characterization of retinal stem cells and their niches in adult zebrafish

Pamela A Raymond, Linda K Barthel, Rebecca L Bernardos, John J Perkowski BMC Developmental Biology 2006, 6:36 (26 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

476
Accesses

Research article   Open Access Highly Accessed

Expression patterns of plexins and neuropilins are consistent with cooperative and separate functions during neural development

Olivier Mauti, Rejina Sadhu, Joelle Gemayel, Matthias Gesemann, Esther T Stoeckli BMC Developmental Biology 2006, 6:32 (17 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

384
Accesses

Research article   Open Access Highly Accessed

Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds

Aimée Zuniga, Frédéric Laurent, Javier Lopez-Rios, Christian Klasen, Nicolas Matt, Rolf Zeller BMC Developmental Biology 2012, 12:23 (13 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Distant cis-regulatory regions scattered through a larger genome region control the highly dynamic expression of Gremlin1 (GREM1), a Bone Morphogenetic Protein (BMP) antagonist, which is key to normal progression of mouse limb bud development.

11.

379
Accesses

Review   Open Access Highly Accessed

Evolution of Hox gene clusters in deuterostomes

Juan Pascual-Anaya, Salvatore D’Aniello, Shigeru Kuratani, Jordi Garcia-Fernàndez BMC Developmental Biology 2013, 13:26 (2 July 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Jordi Garcia-Fernandez and colleagues review our current knowledge of Hox gene cluster evolution in deuterostomes, and discuss ways to increase our understanding of the evolutionary processes of these transcription factors in future.

12.

377
Accesses

Research article   Open Access

Expression of phosphatase of regenerating liver family genes during embryogenesis: an evolutionary developmental analysis among Drosophila, amphioxus, and zebrafish

Ming-Der Lin, Hsun-Tzu Lee, Szu-Chieh Wang, Han-Ru Li, Hsin-Lun Hsien, Kai-Wen Cheng, Yu-Di Chang, Min-Lang Huang, Jr-Kai Yu, Yau-Hung Chen BMC Developmental Biology 2013, 13:18 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

356
Accesses

Methodology article   Open Access

Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice

Laina Freyer, Sonja Nowotschin, Melinda K Pirity, Antonio Baldini, Bernice E Morrow BMC Developmental Biology 2013, 13:33 (23 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

14.

332
Accesses

Research article   Open Access Highly Accessed

Endothelial-specific ablation of Serum Response Factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality

Mary L Holtz, Ravi P Misra BMC Developmental Biology 2008, 8:65 (20 June 2008)

Abstract | Full text | PDF | PubMed

15.

312
Accesses

Research article   Open Access Highly Accessed

The zebrafish transcriptome during early development

Liselotte Vesterlund, Hong Jiao, Per Unneberg, Outi Hovatta, Juha Kere BMC Developmental Biology 2011, 11:30 (24 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

306
Accesses

Research article   Open Access Highly Accessed

Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation

Santanu De, Douglas Kline BMC Developmental Biology 2013, 13:10 (1 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

302
Accesses

Research article   Open Access Highly Accessed

Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells

Wu Ma, Tara Tavakoli, Eric Derby, Yevgeniya Serebryakova, Mahendra S Rao, Mark P Mattson BMC Developmental Biology 2008, 8:90 (22 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

300
Accesses

Methodology article   Open Access Highly Accessed

A bright single-cell resolution live imaging reporter of Notch signaling in the mouse

Sonja Nowotschin, Panagiotis Xenopoulos, Nadine Schrode, Anna-Katerina Hadjantonakis BMC Developmental Biology 2013, 13:15 (25 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Transgenic mice expressing a nuclear-localized fluorescent protein driven by responsive elements, taken from the CBF1 transcription factor, allow single-cell resolution of the Notch signaling pathway, with greater sensitivity and resolution than previous reporter lines.  

19.

285
Accesses

Methodology article   Open Access Highly Accessed

Live imaging and analysis of postnatal mouse retinal development

Philip EB Nickerson, Kara M Ronellenfitch, Nicklaus F Csuzdi, Jamie D Boyd, Perry L Howard, Kerry R Delaney, Robert L Chow BMC Developmental Biology 2013, 13:24 (10 June 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

An improved method, using CO2-independent culture medium and agarose embedding, for live imaging of mouse retinal explants allows tracking of interkinetic nuclear migration within individual retinal cells, and analysis of changes in retinal progenitor cell morphology.

20.

280
Accesses

Research article   Open Access Highly Accessed

Characterization of adipocyte differentiation from human mesenchymal stem cells in bone marrow

Shu-Wen Qian, Xi Li, You-You Zhang, Hai-Yan Huang, Yuan Liu, Xia Sun, Qi-Qun Tang BMC Developmental Biology 2010, 10:47 (7 May 2010)

Abstract | Full text | PDF | PubMed

21.

274
Accesses

Methodology article   Open Access Highly Accessed

Calcium dynamics during fertilization in C. elegans

Aravinthan DT Samuel, Venkatesh N Murthy, Michael O Hengartner BMC Developmental Biology 2001, 1:8 (26 April 2001)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A new technique, based on monitoring the fluorescence of calcium indicator dyes introduced into the cytosol of oocytes, allows the observation of a single calcium transient in C. elegans fertilization in vivo.

22.

272
Accesses

Research article   Open Access

Changes in sub-cellular localisation of trophoblast and inner cell mass specific transcription factors during bovine preimplantation development

Zofia E Madeja, Jaroslaw Sosnowski, Kamila Hryniewicz, Ewelina Warzych, Piotr Pawlak, Natalia Rozwadowska, Berenika Plusa, Dorota Lechniak BMC Developmental Biology 2013, 13:32 (13 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

268
Accesses

Methodology article   Open Access Highly Accessed

Two-color fluorescent in situ hybridization in the embryonic zebrafish brain using differential detection systems

Gilbert Lauter, Iris Söll, Giselbert Hauptmann BMC Developmental Biology 2011, 11:43 (4 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A new methodology for whole mount in situ hybridization (WISH) permits comparison of two different gene expression patterns at the cellular level in the embryonic zebrafish brain with greater sensitivity than conventional methods.

24.

255
Accesses

Database   Open Access Highly Accessed

FishFace: interactive atlas of zebrafish craniofacial development at cellular resolution

B Frank Eames, April DeLaurier, Bonnie Ullmann, Tyler R Huycke, James T Nichols, John Dowd, Marcie McFadden, Mark M Sasaki, Charles B Kimmel BMC Developmental Biology 2013, 13:23 (28 May 2013)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central |  Editor’s summary

The 3D -interactive FishFace Atlas represents a powerful high-resolution tool for learning about growth and development of the zebrafish craniofacial skeleton, providing a reference for comparative and mutational analyses.

25.

251
Accesses

Methodology article   Open Access Highly Accessed

Proteomics of early zebrafish embryos

Vinzenz Link, Andrej Shevchenko, Carl-Philipp Heisenberg BMC Developmental Biology 2006, 6:1 (13 January 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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