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Image of the Month – July 2008
E-cadherin expression in the mouse yolk sac. E-cadherin, an endothelial cell marker, localizes to the apical brush-border surface of the yolk sac but not to the mesodermal layer of an E13.5 mouse embryo. Under confocal microscopy and using antibodies against E-cadherin (green fluorescence) and a second endothelial cell marker PECAM-1 (red fluorescence), the overlap of signal appears yellow. Nuclei are stained with DAPI (blue).
Taken from: Mary L Holtz and Ravi P Misra. BMC Developmental Biology 2008,
8:65 [View article]