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BMC Developmental Biology

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Melissa Norton, MD

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Penelope Webb, PhD

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J. Ann Le Good



BMC  BMC Developmental Biology - Image of the Month


Every month, BMC Developmental Biology features an image from a previously published article as Image of the Month. Publish an article in BMC Developmental Biology and your image could be featured on this page.


Image of the Month – December 2007

TGFbeta receptor rescue of neural tube closure in MZoep zebrafish mutants. Overexpression of an activated form of a TGFbeta receptor (Taram–A*) rescues a neural tube closure defect in MZoep zebrafish embryos, which lack both maternal and zygotic mRNA for oep (one-eyed pinhead) and cannot respond properly to Nodal signals. Taram–A* mRNA and mGFP mRNA were co-injected into one blastomere of 16-cell stage MZoep embryos. The embryos were imaged at 24 h post-fertilization by bright field (top) and fluorescence microscopy (bottom), with green fluorescence visible in the mesoderm-derived anterior mesendoderm and notochord.

Taken from: Allisan Aquilina-Beck, Kristine Ilagan, Qin Liu and Jennifer Liang.
BMC Developmental Biology 2007, 7:126 [View article]


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