Restoring retinal lamination in the zebrafish mosaic eyes mutant
In zebrafish, loss of the protein Mosaic Eyes (Moe) results in defects in brain ventricle formation and retinal formation. Injection of mRNA of an alternatively spliced form of Moe from mice, Epb4.1l5long, rescues zebrafish moe- mutants. The Muller glial cells can be seen to be radially oriented (labeled with anti-Carbonic Anhydrase II, red) with the GFP+ rods (green) and double cones (ZPR-1 antibody, blue) being adjacent to the retinal pigment epithelium.
Taken from: Abbie Jensen et al., 2008, BMC Developmental Biology [View article]
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