BMC Developmental Biology
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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Developmental Biology published by BioMed Central
BMC Developmental Biology is an open access journal publishing original peer-reviewed research articles in the development, growth, differentiation and regeneration of multicellular organisms, including molecular, cellular, tissue, organ and whole organism research.
BMC Developmental Biology (ISSN 1471-213X) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Current Contents, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Developmental Biology 2009, 9 :53
A loss-of-function ras allele (rasKP) causes excessive apoptosis in the Drosophila eye via activation of JNK and, to a lesser extent, Hid, with cell and organ size also affected in the wing.
BMC Developmental Biology 2009, 9 :45
Expression of the transcription factor Yin Yang 2 (YY2) in the cerebellum and neocortex of mice varies during embryonic and postnatal development, suggesting a functional role of YY2 in brain development.
BMC Developmental Biology 2009, 9 :42
When four tick host genes, whose expression is altered by the cattle pathogen Anaplasma marginale, are silenced by RNA interference, no salivary gland infections are seen in the gene-silenced insects, suggesting a role in the pathogen life-cycle in ticks.
Image highlight
Undersized eye of zebrafish embryo with a mutated condensin gene. [more ]
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Research article
Wnt4 is not sufficient to induce lobuloalveolar mammary development Young Chul Kim, Rod J Clark, Francisco Pelegri, Caroline M Alexander BMC Developmental Biology 2009, 9 :55 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development Ita Costello, Christine A Biondi, Jennifer M Taylor, Elizabeth K Bikoff, Elizabeth J Robertson BMC Developmental Biology 2009, 9 :54 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye Yue Wu, Yuan Zhuang, Min Han, Tian Xu, Kejing Deng BMC Developmental Biology 2009, 9 :53 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Expanded progenitor populations, vitreo-retinal abnormalities, and Mleprechaun/patched 2 retina Jonathan Bibliowicz, Jeffrey M Gross BMC Developmental Biology 2009, 9 :52 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
A tamoxifen inducible knock-in allele for investigation of E2A function Mary E Jones, Motonari Kondo, Yuan Zhuang BMC Developmental Biology 2009, 9 :51 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells Jingxian Zhang, Robert J Lipinski, Jerry J Gipp, Aubie K Shaw, Wade Bushman BMC Developmental Biology 2009, 9 :50 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryos Sonja Nowotschin, Anna-Katerina Hadjantonakis BMC Developmental Biology 2009, 9 :49 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Muscle differentiation in a colonial ascidian: organisation, gene expression and evolutionary considerations Valentina Degasperi, Fabio Gasparini, Sebastian M Shimeld, Chiara Sinigaglia, Paolo Burighel, Lucia Manni BMC Developmental Biology 2009, 9 :48 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification Tatsuo Ito, Neelu Yadav, Jaeho Lee, Takayuki Furumatsu, Satoshi Yamashita, Kenji Yoshida, Noboru Taniguchi, Megumi Hashimoto, Megumi Tsuchiya, Toshifumi Ozaki, Martin Lotz, Mark T Bedford, Hiroshi Asahara BMC Developmental Biology 2009, 9 :47 (2 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors Perrine Castets, Svetlana Maugenre, Corine Gartioux, Mathieu Rederstorff, Alain Krol, Alain Lescure, Shahragim Tajbakhsh, Val BMC Developmental Biology 2009, 9 :46 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps Jochen Trauner, Johannes Schinko, Marce D Lorenzen, Teresa D Shippy, Ernst A Wimmer, Richard W Beeman, Martin Klingler, Gregor Bucher, Susan J Brown BMC Biology 2009, 7 :73 (5 [Abstract ] [Provisional PDF ]
Research
The molecular basis for stability of heterochromatin-mediated silencing in mammals
Kyoko Hiragami-Hamada, Sheila Q Xie, Alexander Saveliev, Santiago Uribe-Lewis, Ana Pombo, Richard Festenstein Epigenetics & Chromatin 2009, 2 :14 (4 [Abstract ] [Provisional PDF ]
Research article
Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function Lorena Varela-Nallar, Catalina P. Grabowski, Ivan E. Alfaro, Alejandra R. Alvarez, Nibaldo C. Inestrosa Neural Development 2009, 4 :41 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Promotion of embryonic cortico-cerebral neuronogenesis by miR-124 Nicola Antonio Maiorano, Antonello Mallamaci Neural Development 2009, 4 :40 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Temporal patterns of broad isoform expression during the development of neuronal lineages in Drosophila
Baohua Zhou, Darren W Williams, Janet Altman, Lynn M Riddiford, James W Truman Neural Development 2009, 4 :39 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Editorial
Epigenetics & Chromatin celebrates its first anniversary Steven Henikoff, Frank Grosveld Epigenetics & Chromatin 2009, 2 :13 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy R Geoffrey Burwell, Ranjit K Aujla, Michael P Grevitt, Peter H Dangerfield, Alan Moulton, Tabitha L Randell, Susan I Anderson Scoliosis 2009, 4 :24 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
EST and microarray analysis of horn development in Onthophagus beetles Teiya Kijimoto, James Costello, Zuojian Tang, Armin P Moczek, Justen Andrews BMC Genomics 2009, 10 :504 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting Grace E Snow, Allison C Kasper, Alexander M Busch, Elisabeth Schwarz, Katherine E Ewings, Thomas Bee, Michael J Spinella, Ethan Dmitrovsky, Sarah J Freemantle BMC Cancer 2009, 9 :383 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Pollen development in Annona cherimola Mill. (Annonaceae). Implications for the evolution of aggregated pollen Jorge Lora, Pilar S Testillano, Maria C Risueno, Jose I Hormaza, Maria Herrero BMC Plant Biology 2009, 9 :129 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
ller glial reactivity in the zebrafish leprechaun/patched2 retina
rie Allamand, Pascale Guicheney