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	1. 711 Accesses	Research article Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people MRC/BHF Heart Protection Study Collaborative Group BMC Clinical Pharmacology 2009, 9:6 (31 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Simvastatin treatment for patients at high risk of cardiovascular events or with diabetes results in only a minor increase in the risk of myopathy and hepatobiliary diseases over 5 years of use.
	2. 677 Accesses	Research article Finasteride induced depression: a prospective study Babak Rahimi-Ardabili, Ramin Pourandarjani, Peiman Habibollahi, Amir Mualeki BMC Clinical Pharmacology 2006, 6:7 (7 October 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	3. 569 Accesses	Research article Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics Andres F Zuluaga, Maria Agudelo, Carlos A Rodriguez, Omar Vesga BMC Clinical Pharmacology 2009, 9:1 (16 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Pharmaceutical equivalence of generic intravenous antibiotics can be assessed prior to their clinical use by providing information about potency and efficacy using a new microbiological assay with reference bacteria
	4. 471 Accesses	Research article Errors in medication history at hospital admission: prevalence and predicting factors Lina M Hellström, Åsa Bondesson, Peter Höglund, Tommy Eriksson BMC Clinical Pharmacology 2012, 12:9 (3 April 2012) Abstract \| Full text \| PDF \| PubMed
	5. 430 Accesses	Research article Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A - Medical results James B Adams, Matthew Baral, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Andrea Hensley, Irene Zappia, Sanford Newmark, Eva Gehn, Robert A Rubin, Ken Mitchell, Jeff Bradstreet, Jane El-Dahr BMC Clinical Pharmacology 2009, 9:16 (23 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 408 Accesses	Case report Intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump: A case report Imran Mohammed, Asif Hussain BMC Clinical Pharmacology 2004, 4:6 (9 August 2004) Abstract \| Full text \| PDF \| PubMed
	7. 403 Accesses	Research article Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers Peter M Dewland, Sandie Reader, Phillip Berry BMC Clinical Pharmacology 2009, 9:19 (4 December 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The time to maximum blood concentration of ibuprofen is cut from 90 minutes to just 35 minutes if ibuprofen sodium dihydrate is taken rather than the standard formulation, but adding poloxamer makes no significant difference to bioavailability.
	8. 369 Accesses	Research article Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects Howard A Smithline, Michael Donnino, David J Greenblatt BMC Clinical Pharmacology 2012, 12:4 (4 February 2012) Abstract \| Full text \| PDF \| PubMed
	9. 337 Accesses	Research article Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria George I Eluwa, Titilope Badru, Kesiena J Akpoigbe BMC Clinical Pharmacology 2012, 12:7 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
	10. 322 Accesses	Research article Sodium pentosan polysulfate resulted in cartilage improvement in knee osteoarthritis - An open clinical trial- Kenji Kumagai, Susumu Shirabe, Noriaki Miyata, Masakazu Murata, Atsushi Yamauchi, Yasuhumi Kataoka, Masami Niwa BMC Clinical Pharmacology 2010, 10:7 (28 March 2010) Abstract \| Full text \| PDF \| PubMed
	11. 308 Accesses	Research article Quality and safety of medication use in primary care: consensus validation of a new set of explicit medication assessment criteria and prioritisation of topics for improvement Tobias Dreischulte, Aileen M Grant, Colin McCowan, John J McAnaw, Bruce Guthrie BMC Clinical Pharmacology 2012, 12:5 (8 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A new set of criteria to assess medication quality and safety, that complements existing medication assessment instruments, can be implemented in electronic data sets and focuses on common and severe preventable drug related morbidity in primary care.
	12. 305 Accesses	Research article Traumeel S^®for pain relief following hallux valgus surgery: a randomized controlled trial Shepherd R Singer, Michal Amit-Kohn, Samuel Weiss, Jonathan Rosenblum, Guy Maoz, Noah Samuels, Esther Lukasiewicz, Laurence Freedman, Ora Paltiel, Menachem Itzchaki, Meir Niska, Menachem Oberbaum BMC Clinical Pharmacology 2010, 10:9 (12 April 2010) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	13. 292 Accesses	Research article The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol Trevor Tanner, Sue Aspley, Andrew Munn, Tracy Thomas BMC Clinical Pharmacology 2010, 10:10 (5 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Paracetemol is absorbed significantly faster when taken in a combination dose with ibuprofen compared to when taken in isolation, with greater blood plasma concentrations of both being reached earlier, offering potentially enhanced pain relief.
	14. 291 Accesses	Research article The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903] Edward Mills, Jonathan Prousky, Gannady Raskin, Joel Gagnier, Beth Rachlis, Victor M Montori, David Juurlink BMC Clinical Pharmacology 2003, 3:4 (13 November 2003) Abstract \| Full text \| PDF \| PubMed
	15. 278 Accesses	Research article A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka S M D K Ganga Senarathna, Shalini Ranganathan, Nick Buckley, Rohini Fernandopulle BMC Clinical Pharmacology 2012, 12:6 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	16. 271 Accesses	Research article Effect of exenatide on the pharmacokinetics of a combination oral contraceptive in healthy women: an open-label, randomised, crossover trial Prajakti A Kothare, Mary E Seger, Justin Northrup, Kenneth Mace, Malcolm I Mitchell, Helle Linnebjerg BMC Clinical Pharmacology 2012, 12:8 (19 March 2012) Abstract \| Provisional PDF \| PubMed
	17. 268 Accesses	Technical advance Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA Armin Buchwald, Karl Winkler, Thomas Epting BMC Clinical Pharmacology 2012, 12:2 (11 January 2012) Abstract \| Full text \| PDF \| PubMed
	18. 251 Accesses	Research article Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls Pekka Rapeli, Carola Fabritius, Hannu Alho, Mikko Salaspuro, Kristian Wahlbeck, Hely Kalska BMC Clinical Pharmacology 2007, 7:5 (12 June 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19. 250 Accesses	Debate Promiscuous drugs compared to selective drugs (promiscuity can be a virtue) Simon K Mencher, Long G Wang BMC Clinical Pharmacology 2005, 5:3 (26 April 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Truly selective drugs may be less desirable than more 'promiscuous' drugs which correct the imbalance of several molecules involved in a disease process; this viewpoint has implications for current research trends focused on drug selectivity.
	20. 249 Accesses	Research article Effects of paliperidone extended release on the symptoms and functioning of schizophrenia Min-Wei Huang, Tsung-Tsair Yang, Po-Ren Ten, Po-Wen Su, Bo-Jian Wu, Chin-Hong Chan, Tsuo-Hung Lan, I-Chao Liu, Wei-Cheh Chiu, Chun-Ying Li, Kuo-Sheng Cheng, Yu-Chi Yeh BMC Clinical Pharmacology 2012, 12:1 (6 January 2012) Abstract \| Full text \| PDF \| PubMed
	21. 240 Accesses	Research article Systematic review of dexketoprofen in acute and chronic pain R Andrew Moore, Jodie Barden BMC Clinical Pharmacology 2008, 8:11 (31 October 2008) Abstract \| Full text \| PDF \| PubMed
	22. 238 Accesses	Research article Reporting of adverse drug reactions in randomised controlled trials – a systematic survey Yoon Loke, Sheena Derry BMC Clinical Pharmacology 2001, 1:3 (12 September 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Trial reports of adverse drug effects often fail to provide sufficient methodological information and lack of coherency in reporting the rates of adverse drug reactions, thus making comparative evaluation potentially unreliable, a systematic survey shows.
	23. 228 Accesses	Research article Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials Oliver Löwenstein, Petra Leyendecker, Eberhard A Lux, Mark Blagden, Karen H Simpson, Michael Hopp, Björn Bosse, Karen Reimer BMC Clinical Pharmacology 2010, 10:12 (29 September 2010) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Chronic non-malignant pain sufferers with opiod-induced constipation have improved bowel function without compromising analgesic efficacy when taking a combination of oxycodone and naloxone pain relief, compared to patients taking oxycodone on its own.
	24. 227 Accesses	Research article Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study Andrew Spencer, Andrew Roberts, Nola Kennedy, Christina Ravera, Serge Cremers, Sanela Bilic, Terry Neeman, Michael Copeman, Horst Schran, Kevin Lynch BMC Clinical Pharmacology 2008, 8:2 (31 March 2008) Abstract \| Full text \| PDF \| PubMed
	25. 211 Accesses	Technical advance High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection Anders Andersen, David J Warren, Paal F Brunsvig, Steinar Aamdal, Gunnar B Kristensen, Harald Olsen BMC Clinical Pharmacology 2006, 6:2 (13 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A high performance liquid chromatography method which uses UV detection is capable of quantifying nM concentrations of taxanes in human plasma samples, making it suitable for the sensitive monitoring of taxane levels in people receiving low dose therapy for cancer treatment.