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		Research article Hepatitis B assays in serum, plasma and whole blood on filter paper Theodor K Mayer, Roberto L Vargas, Ann E Knebel, Scott A Williams, Sean P Culver, Daniel M Clark, Louise R King BMC Clinical Pathology 2012, 12:8 (20 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas Sveinung W Sorbye, Thomas K Kilvaer, Andrej Valkov, Tom Donnem, Eivind Smeland, Khalid Al-Shibli, Roy M Bremnes, Lill-Tove Busund BMC Clinical Pathology 2012, 12:7 (3 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Increased co-expression of M-CSF and TGF-beta in soft tissue sarcoma, and increased expression of Ki67 in peritumoral capsule are independent negative prognostic factors for survival, suggesting that innate immunity markers may serve as prognosticators in soft tissue sarcomas.
		Research article Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional study Shweta Ujaoney, Mukta B Motwani, Shirish Degwekar, Vijay Wadhwan, Prajakta Zade, Minal Chaudhary, Vinay Hazarey, Tushar P Thakre, Manju Mamtani BMC Clinical Pathology 2012, 12:6 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas Sveinung W Sorbye, Thomas K Kilvaer, Andrej Valkov, Tom Donnem, Eivind Smeland, Khalid Al-Shibli, Roy M Bremnes, Lill-Tove Busund BMC Clinical Pathology 2012, 12:5 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas Zhen Haining, Nobuyuki Kawai, Keisuke Miyake, Masaki Okada, Shuichi Okubo, Xiang Zhang, Zhou Fei, Takashi Tamiya BMC Clinical Pathology 2012, 12:4 (28 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Large-type amino acid transporter 1 (LAT1) and heavy chain of 4F2 cell surface antigen (4F2hc) are expressed in human gliomas and their expression levels correlate with pathological grade and proliferation, with LAT1 being associated with glioma angiogenesis.
		Technical advance Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization Jens Mollerup, Ulla Henriksen, Sven Müller, Andreas Schønau BMC Clinical Pathology 2012, 12:3 (14 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer Marco Palma, Lissett Lopez, Margarita García, Nuria de Roja, Tamara Ruiz, Julita García, Elisabet Rosell, Carmen Vela, Paloma Rueda, María-Jose Rodriguez BMC Clinical Pathology 2012, 12:2 (9 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps Matthew D Krasowski, Rebecca M Wilcoxon, Joel Miron BMC Clinical Pathology 2012, 12:1 (12 January 2012) Abstract \| Full text \| PDF \| PubMed
		Technical advance Molecular preservation by extraction and fixation, mPREF: a method for small molecule biomarker analysis and histology on exactly the same tissue Jeffrey R Shuster, Raymond S Lance, Dean A Troyer BMC Clinical Pathology 2011, 11:14 (21 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A modified fixation process preserves prostatectomy tissue biopsy integrity, allowing histology and multiple small molecule biomarker analyses to be performed on the same highly localised sample, enabling the distinction between normal and cancer-containing tissue specimens.
		Research article Decrease in thyroid adenoma associated (THADA) expression is a marker of dedifferentiation of thyroid tissue Lars Kloth, Gazanfer Belge, Käte Burchardt, Siegfried Loeschke, Werner Wosniok, Xin Fu, Rolf Nimzyk, Salah A Mohamed, Norbert Drieschner, Volkhard Rippe, Jörn Bullerdiek BMC Clinical Pathology 2011, 11:13 (4 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary THADA (thyroid adenoma associated) protein levels are higher in the normal thyroid compared to other tissues, but significantly down-regulated in malignant thyroid tumors, suggesting THADA plays a role in maintaining the differentiated state.
		Research article Cortisol in hair measured in young adults - a biomarker of major life stressors? Jerker Karlén, Johnny Ludvigsson, Anneli Frostell, Elvar Theodorsson, Tomas Faresjö BMC Clinical Pathology 2011, 11:12 (25 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Increased cortisol levels in hair may serve as a biomarker of increased cortisol production reflecting exposure to major life stressors or extended physiological illness, with serious life events potentially raising hair hormone levels more than perceived stress.
		Research article Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing Matthias Wielscher, Walter Pulverer, Johannes Peham, Manuela Hofner, Christine F Rappaport, Christian Singer, Christof Jungbauer, Christa Nöhammer, Andreas Weinhäusel BMC Clinical Pathology 2011, 11:11 (6 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Functional characterization of the complement receptor type 1 and its circulating ligands in patients with schizophrenia Arsen Arakelyan, Roksana Zakharyan, Aren Khoyetsyan, David Poghosyan, Rouben Aroutiounian, Frantisek Mrazek, Martin Petrek, Anna Boyajyan BMC Clinical Pathology 2011, 11:10 (25 August 2011) Abstract \| Full text \| PDF \| PubMed
		Technical advance LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood Daisuke Okuzaki, Shoichi Kimura, Norikazu Yabuta, Toshinari Ohmine, Hiroshi Nojima BMC Clinical Pathology 2011, 11:9 (17 August 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary LeukoCatch is a novel tool that can selectively obtain leukocyte extracts without hemoglobin from blood samples and results in a protein recovery rate at least four times better than that of the conventional centrifugation method.
		Research article Plasma concentrations of 25-hydroxyvitamin D among Jordanians: Effect of biological and habitual factors on vitamin D status Eyad M Mallah, Mohammad F Hamad, Mays A ElManaseer, Nidal A Qinna, Nasir M Idkaidek, Tawfiq A Arafat, Khalid Z Matalka BMC Clinical Pathology 2011, 11:8 (4 August 2011) Abstract \| Full text \| PDF \| PubMed
		Case report Intranodal palisaded myofibroblastoma originating from retroperitoneum: an unusual origin Jayesh Sagar, Athanasia Vargiamidou, Hemachandran Manikkapurath BMC Clinical Pathology 2011, 11:7 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Effects of different centrifugation conditions on clinical chemistry and Immunology test results Elisabeth I Minder, Adrian Schibli, Dagmar Mahrer, Predrag Nesic, Kathrin Plüer BMC Clinical Pathology 2011, 11:6 (10 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Centrifuging heparinized blood samples for either seven minutes at 1870g or ten minutes at 2180g provides identical test results compared to those centrifuged under the same conditions for fifteen minutes as proposed by WHO.
		Research article Hemoglobin estimation by the HemoCue^®portable hemoglobin photometer in a resource poor setting Bernard Nkrumah, Samuel Nguah, Nimako Sarpong, Denise Dekker, Ali Idriss, Juergen May, Yaw Adu-Sarkodie BMC Clinical Pathology 2011, 11:5 (21 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Immunohistochemical detection of laminin-1 and Ki-67 in radicular cysts and keratocystic odontogenic tumors Mohamed S Ayoub, Houry M Baghdadi, Moataz El-Kholy BMC Clinical Pathology 2011, 11:4 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer Juho Konsti, Mikael Lundin, Heikki Joensuu, Tiina Lehtimäki, Harri Sihto, Kaija Holli, Taina Turpeenniemi-Hujanen, Vesa Kataja, Liisa Sailas, Jorma Isola, Johan Lundin BMC Clinical Pathology 2011, 11:3 (25 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An automated analysis of Ki-67 expression run on a virtual microscopy platform in breast cancer samples is comparable to visual assessment, and is a significant and independent predictor of outcome.
		Research article Differential effects of frozen storage on the molecular detection of bacterial taxa that inhabit the nasopharynx Brenda A Kwambana, Nuredin I Mohammed, David Jeffries, Mike Barer, Richard A Adegbola, Martin Antonio BMC Clinical Pathology 2011, 11:2 (24 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma Tanner L Bartholow, Uma R Chandran, Michael J Becich, Anil V Parwani BMC Clinical Pathology 2011, 11:1 (14 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Radixin shows a lower expression level in prostatic adenocarcinoma and normal tissue adjacent to adenocarcinoma than other types of prostate tissue and it may have potential as a clinically useful biomarker.
		Technical advance COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma Colin C Pritchard, Laura Akagi, Poluru L Reddy, Loren Joseph, Jonathan F Tait BMC Clinical Pathology 2010, 10:6 (26 November 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The COLD-PCR enhanced melting curve assay can detect down to 1% KRAS-mutant alleles in a wild type background and significantly improves diagnostic accuracy compared to traditional PCR and direct sequencing.
		Research article Use of the GenoType^®MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda Joel Bazira, Benon B Asiimwe, Moses L Joloba, Fred Bwanga, Mecky I Matee BMC Clinical Pathology 2010, 10:5 (6 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The GenoType(R) MTBDRplus assay detects low levels of resistance to antibiotics in tuberculosis patients in Uganda, indicating that this technique may be suitable for use in diagnostic laboratories in countries lacking the capacity to undertake drug susceptibility testing.
		Research article Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study Wendela L Greven, Jitty M Smit, Johannes H Rommes, Peter E Spronk BMC Clinical Pathology 2010, 10:4 (25 May 2010) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Hepatitis B assays in serum, plasma and whole blood on filter paper Theodor K Mayer, Roberto L Vargas, Ann E Knebel, Scott A Williams, Sean P Culver, Daniel M Clark, Louise R King BMC Clinical Pathology 2012, 12:8 (20 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas Sveinung W Sorbye, Thomas K Kilvaer, Andrej Valkov, Tom Donnem, Eivind Smeland, Khalid Al-Shibli, Roy M Bremnes, Lill-Tove Busund BMC Clinical Pathology 2012, 12:7 (3 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Increased co-expression of M-CSF and TGF-beta in soft tissue sarcoma, and increased expression of Ki67 in peritumoral capsule are independent negative prognostic factors for survival, suggesting that innate immunity markers may serve as prognosticators in soft tissue sarcomas.
		Research article Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional study Shweta Ujaoney, Mukta B Motwani, Shirish Degwekar, Vijay Wadhwan, Prajakta Zade, Minal Chaudhary, Vinay Hazarey, Tushar P Thakre, Manju Mamtani BMC Clinical Pathology 2012, 12:6 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas Sveinung W Sorbye, Thomas K Kilvaer, Andrej Valkov, Tom Donnem, Eivind Smeland, Khalid Al-Shibli, Roy M Bremnes, Lill-Tove Busund BMC Clinical Pathology 2012, 12:5 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas Zhen Haining, Nobuyuki Kawai, Keisuke Miyake, Masaki Okada, Shuichi Okubo, Xiang Zhang, Zhou Fei, Takashi Tamiya BMC Clinical Pathology 2012, 12:4 (28 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Large-type amino acid transporter 1 (LAT1) and heavy chain of 4F2 cell surface antigen (4F2hc) are expressed in human gliomas and their expression levels correlate with pathological grade and proliferation, with LAT1 being associated with glioma angiogenesis.
		Technical advance Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization Jens Mollerup, Ulla Henriksen, Sven Müller, Andreas Schønau BMC Clinical Pathology 2012, 12:3 (14 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer Marco Palma, Lissett Lopez, Margarita García, Nuria de Roja, Tamara Ruiz, Julita García, Elisabet Rosell, Carmen Vela, Paloma Rueda, María-Jose Rodriguez BMC Clinical Pathology 2012, 12:2 (9 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps Matthew D Krasowski, Rebecca M Wilcoxon, Joel Miron BMC Clinical Pathology 2012, 12:1 (12 January 2012) Abstract \| Full text \| PDF \| PubMed
		Technical advance Molecular preservation by extraction and fixation, mPREF: a method for small molecule biomarker analysis and histology on exactly the same tissue Jeffrey R Shuster, Raymond S Lance, Dean A Troyer BMC Clinical Pathology 2011, 11:14 (21 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A modified fixation process preserves prostatectomy tissue biopsy integrity, allowing histology and multiple small molecule biomarker analyses to be performed on the same highly localised sample, enabling the distinction between normal and cancer-containing tissue specimens.
		Research article Decrease in thyroid adenoma associated (THADA) expression is a marker of dedifferentiation of thyroid tissue Lars Kloth, Gazanfer Belge, Käte Burchardt, Siegfried Loeschke, Werner Wosniok, Xin Fu, Rolf Nimzyk, Salah A Mohamed, Norbert Drieschner, Volkhard Rippe, Jörn Bullerdiek BMC Clinical Pathology 2011, 11:13 (4 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary THADA (thyroid adenoma associated) protein levels are higher in the normal thyroid compared to other tissues, but significantly down-regulated in malignant thyroid tumors, suggesting THADA plays a role in maintaining the differentiated state.
		Research article Cortisol in hair measured in young adults - a biomarker of major life stressors? Jerker Karlén, Johnny Ludvigsson, Anneli Frostell, Elvar Theodorsson, Tomas Faresjö BMC Clinical Pathology 2011, 11:12 (25 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Increased cortisol levels in hair may serve as a biomarker of increased cortisol production reflecting exposure to major life stressors or extended physiological illness, with serious life events potentially raising hair hormone levels more than perceived stress.
		Research article Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing Matthias Wielscher, Walter Pulverer, Johannes Peham, Manuela Hofner, Christine F Rappaport, Christian Singer, Christof Jungbauer, Christa Nöhammer, Andreas Weinhäusel BMC Clinical Pathology 2011, 11:11 (6 September 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Functional characterization of the complement receptor type 1 and its circulating ligands in patients with schizophrenia Arsen Arakelyan, Roksana Zakharyan, Aren Khoyetsyan, David Poghosyan, Rouben Aroutiounian, Frantisek Mrazek, Martin Petrek, Anna Boyajyan BMC Clinical Pathology 2011, 11:10 (25 August 2011) Abstract \| Full text \| PDF \| PubMed
		Technical advance LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood Daisuke Okuzaki, Shoichi Kimura, Norikazu Yabuta, Toshinari Ohmine, Hiroshi Nojima BMC Clinical Pathology 2011, 11:9 (17 August 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary LeukoCatch is a novel tool that can selectively obtain leukocyte extracts without hemoglobin from blood samples and results in a protein recovery rate at least four times better than that of the conventional centrifugation method.
		Research article Plasma concentrations of 25-hydroxyvitamin D among Jordanians: Effect of biological and habitual factors on vitamin D status Eyad M Mallah, Mohammad F Hamad, Mays A ElManaseer, Nidal A Qinna, Nasir M Idkaidek, Tawfiq A Arafat, Khalid Z Matalka BMC Clinical Pathology 2011, 11:8 (4 August 2011) Abstract \| Full text \| PDF \| PubMed
		Case report Intranodal palisaded myofibroblastoma originating from retroperitoneum: an unusual origin Jayesh Sagar, Athanasia Vargiamidou, Hemachandran Manikkapurath BMC Clinical Pathology 2011, 11:7 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Effects of different centrifugation conditions on clinical chemistry and Immunology test results Elisabeth I Minder, Adrian Schibli, Dagmar Mahrer, Predrag Nesic, Kathrin Plüer BMC Clinical Pathology 2011, 11:6 (10 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Centrifuging heparinized blood samples for either seven minutes at 1870g or ten minutes at 2180g provides identical test results compared to those centrifuged under the same conditions for fifteen minutes as proposed by WHO.
		Research article Hemoglobin estimation by the HemoCue^®portable hemoglobin photometer in a resource poor setting Bernard Nkrumah, Samuel Nguah, Nimako Sarpong, Denise Dekker, Ali Idriss, Juergen May, Yaw Adu-Sarkodie BMC Clinical Pathology 2011, 11:5 (21 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Immunohistochemical detection of laminin-1 and Ki-67 in radicular cysts and keratocystic odontogenic tumors Mohamed S Ayoub, Houry M Baghdadi, Moataz El-Kholy BMC Clinical Pathology 2011, 11:4 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer Juho Konsti, Mikael Lundin, Heikki Joensuu, Tiina Lehtimäki, Harri Sihto, Kaija Holli, Taina Turpeenniemi-Hujanen, Vesa Kataja, Liisa Sailas, Jorma Isola, Johan Lundin BMC Clinical Pathology 2011, 11:3 (25 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An automated analysis of Ki-67 expression run on a virtual microscopy platform in breast cancer samples is comparable to visual assessment, and is a significant and independent predictor of outcome.
		Research article Differential effects of frozen storage on the molecular detection of bacterial taxa that inhabit the nasopharynx Brenda A Kwambana, Nuredin I Mohammed, David Jeffries, Mike Barer, Richard A Adegbola, Martin Antonio BMC Clinical Pathology 2011, 11:2 (24 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma Tanner L Bartholow, Uma R Chandran, Michael J Becich, Anil V Parwani BMC Clinical Pathology 2011, 11:1 (14 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Radixin shows a lower expression level in prostatic adenocarcinoma and normal tissue adjacent to adenocarcinoma than other types of prostate tissue and it may have potential as a clinically useful biomarker.
		Technical advance COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma Colin C Pritchard, Laura Akagi, Poluru L Reddy, Loren Joseph, Jonathan F Tait BMC Clinical Pathology 2010, 10:6 (26 November 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The COLD-PCR enhanced melting curve assay can detect down to 1% KRAS-mutant alleles in a wild type background and significantly improves diagnostic accuracy compared to traditional PCR and direct sequencing.
		Research article Use of the GenoType^®MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda Joel Bazira, Benon B Asiimwe, Moses L Joloba, Fred Bwanga, Mecky I Matee BMC Clinical Pathology 2010, 10:5 (6 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The GenoType(R) MTBDRplus assay detects low levels of resistance to antibiotics in tuberculosis patients in Uganda, indicating that this technique may be suitable for use in diagnostic laboratories in countries lacking the capacity to undertake drug susceptibility testing.
		Research article Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study Wendela L Greven, Jitty M Smit, Johannes H Rommes, Peter E Spronk BMC Clinical Pathology 2010, 10:4 (25 May 2010) Abstract \| Full text \| PDF \| PubMed