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BMC Chemical Biology

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Danielle Burgess PhD


Welcome to BMC Chemical Biology published by BioMed Central
BMC Chemical Biology is an open access journal publishing original peer-reviewed research articles in the application of chemistry to the investigation of biological processes and systems including the biosynthesis and metabolism of natural compounds, drug design and complex molecular rearrangements occurring in living organisms. BMC Chemical Biology (ISSN 1472-6769) is indexed/tracked/covered by PubMed, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.



BMC Featured articles

KEGG
BMC Chemical Biology 2009, 9:5
Proteins with high lysine content and high turnover are more susceptible to covalent modification by xenobiotic reactive metabolites, and an analysis of directly-interacting partners of the most common known targets suggests how adduction has toxic effects.


BMC  Latest articles published in BMC Chemical Biology        [more info]


Research article
Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners
Jianwen Fang, Yakov M Koen, Robert P Hanzlik
BMC Chemical Biology 2009, 9:5 (12June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Local and global modes of drug action in biochemical networks
Jean-Marc Schwartz, Jose C Nacher
BMC Chemical Biology 2009, 9:4 (7April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Chemical tools selectively target components of the PKA system
Daniela Bertinetti, Sonja Schweinsberg, Susanne E Hanke, Frank Schwede, Oliver Bertinetti, Stephan Drewianka, Hans-Gottfried Genieser, Friedrich W Herberg
BMC Chemical Biology 2009, 9:3 (12February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus
John Paul Pezacki, Selena M Sagan, Angela M Tonary, Yanouchka Rouleau, Sylvie Blanger, Lubica Supekova, Andrew I Su
BMC Chemical Biology 2009, 9:2 (16January2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue
Patrick Chne, Jolle Rudloff, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean-Marc Schlaeppi, Rita Schmitz, Thomas Radimerski
BMC Chemical Biology 2009, 9:1 (7January2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Chemogenetic fingerprinting by analysis of cellular growth dynamics
Jonas Warringer, Dragi Anevski, Beidong Liu, Anders Blomberg
BMC Chemical Biology 2008, 8:3 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II
Maria Hgg Olofsson, Aleksandra Mandic Havelka, Slavica Brnjic, Maria C Shoshan, Stig Linder
BMC Chemical Biology 2008, 8:2 (1August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae
Lorena Norambuena, Jan Zouhar, Glenn R Hicks, Natasha V Raikhel
BMC Chemical Biology 2008, 8:1 (7January2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Enhancement of intracellular -tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation
Yuichiro Tanaka, Leslie A Lesoon Wood, Robert V Cooney
BMC Chemical Biology 2007, 7:2 (3July2007)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The effect of amino acid deletions and substitutions in the longest loop of GFP
Gabriela Flores-Ramrez, Manuel Rivera, Alfredo Morales-Pablos, Joel Osuna, Xavier Sobern, Paul Gaytn
BMC Chemical Biology 2007, 7:1 (26June2007)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate
Christina Ramel, Micha Tobler, Martin Meyer, Laurent Bigler, Marc-Olivier Ebert, Barbara Schellenberg, Robert Dudler
BMC Biochemistry 2009, 10:26 (28October2009)
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Research
Breaking the hierarchy - a new cluster selection mechanism for hierarchical clustering methods
Lszl A Zahornszky, Gyula Y Katona, Pter Hri, Andrs Mlnsi-Csizmadia, Katharina A Zweig, Gergely Zahornszky-Khalmi
Algorithms for Molecular Biology 2009, 4:12 (19October2009)
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Research article
Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells
Hiroshi Wada, Hiroaki Nagano, Hirofumi Yamamoto, Takehiro Noda, Masahiro Murakami, Shogo Kobayashi, Shigeru Marubashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori
BMC Cancer 2009, 9:361 (12October2009)
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Research article
Conformational changes and loose packing promote E. coli Tryptophanase cold lability
Anna Kogan, Garik Y Gdalevsky, Rivka Cohen-Luria, Yehuda Goldgur, Robert S Phillips, Abraham H Parola, Orna Almog
BMC Structural Biology 2009, 9:65 (8October2009)
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Review
Eps15: a multifunctional adaptor protein regulating intracellular trafficking
Paul MP van Bergen en Henegouwen
Cell Communication and Signaling 2009, 7:24 (8October2009)
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Research article
Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch
Suvi Sutela, Karoliina Niemi, Jaanika Edesi, Tapio Laakso, Pekka Saranp, Jaana Vuosku, Riina Mkel, Heidi Tiimonen, Vincent L Chiang, Janne Koskimki, Marja Suorsa, Riitta Julkunen-Tiitto, Hely Hggman
BMC Plant Biology 2009, 9:124 (29September2009)
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Research
Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa
Prasan Tangyuenyongwatana, Jariya Kowapradit, Praneet Opanasopit, Wandee Gritsanapan
Chinese Medicine 2009, 4:19 (25September2009)
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Methodology article
MALS: an efficient strategy for multiple site-directed mutagenesis employing a combination of DNA amplification, ligation and suppression PCR
Alexey A Fushan, Dennis T Drayna
BMC Biotechnology 2009, 9:83 (24September2009)
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Research article
Mirrors in the PDB: left-handed -turns guide design with D-amino acids
Srinivas Annavarapu, Vikas Nanda
BMC Structural Biology 2009, 9:61 (22September2009)
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Research article
Prediction of antigenic epitopes on protein surfaces by consensus scoring
Shide Liang, Dandan Zheng, Chi Zhang, Martin Zacharias
BMC Bioinformatics 2009, 10:302 (22September2009)
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