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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Chemical Biology published by BioMed Central
BMC Chemical Biology is an open access journal publishing original peer-reviewed research articles in the application of chemistry to the investigation of biological processes and systems including the biosynthesis and metabolism of natural compounds, drug design and complex molecular rearrangements occurring in living organisms.
BMC Chemical Biology (ISSN 1472-6769) is indexed/tracked/covered by PubMed, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Chemical Biology 2009, 9 :5
Proteins with high lysine content and high turnover are more susceptible to covalent modification by xenobiotic reactive metabolites, and an analysis of directly-interacting partners of the most common known targets suggests how adduction has toxic effects.
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Research article
Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners Jianwen Fang, Yakov M Koen, Robert P Hanzlik BMC Chemical Biology 2009, 9 :5 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Local and global modes of drug action in biochemical networks Jean-Marc Schwartz, Jose C Nacher BMC Chemical Biology 2009, 9 :4 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Chemical tools selectively target components of the PKA system Daniela Bertinetti, Sonja Schweinsberg, Susanne E Hanke, Frank Schwede, Oliver Bertinetti, Stephan Drewianka, Hans-Gottfried Genieser, Friedrich W Herberg BMC Chemical Biology 2009, 9 :3 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus John Paul Pezacki, Selena M Sagan, Angela M Tonary, Yanouchka Rouleau, Sylvie B BMC Chemical Biology 2009, 9 :2 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue Patrick Ch BMC Chemical Biology 2009, 9 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Chemogenetic fingerprinting by analysis of cellular growth dynamics Jonas Warringer, Dragi Anevski, Beidong Liu, Anders Blomberg BMC Chemical Biology 2008, 8 :3 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II Maria H BMC Chemical Biology 2008, 8 :2 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae Lorena Norambuena, Jan Zouhar, Glenn R Hicks, Natasha V Raikhel BMC Chemical Biology 2008, 8 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Enhancement of intracellular Yuichiro Tanaka, Leslie A Lesoon Wood, Robert V Cooney BMC Chemical Biology 2007, 7 :2 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The effect of amino acid deletions and substitutions in the longest loop of GFP Gabriela Flores-Ram BMC Chemical Biology 2007, 7 :1 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate Christina Ramel, Micha Tobler, Martin Meyer, Laurent Bigler, Marc-Olivier Ebert, Barbara Schellenberg, Robert Dudler BMC Biochemistry 2009, 10 :26 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Breaking the hierarchy - a new cluster selection mechanism for hierarchical clustering methods L Algorithms for Molecular Biology 2009, 4 :12 (19 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells Hiroshi Wada, Hiroaki Nagano, Hirofumi Yamamoto, Takehiro Noda, Masahiro Murakami, Shogo Kobayashi, Shigeru Marubashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori BMC Cancer 2009, 9 :361 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Conformational changes and loose packing promote E. coli Tryptophanase cold lability Anna Kogan, Garik Y Gdalevsky, Rivka Cohen-Luria, Yehuda Goldgur, Robert S Phillips, Abraham H Parola, Orna Almog BMC Structural Biology 2009, 9 :65 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Review
Eps15: a multifunctional adaptor protein regulating intracellular trafficking Paul MP van Bergen en Henegouwen Cell Communication and Signaling 2009, 7 :24 (8 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch Suvi Sutela, Karoliina Niemi, Jaanika Edesi, Tapio Laakso, Pekka Saranp BMC Plant Biology 2009, 9 :124 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Cellular transport of anti-inflammatory pro-drugs originated from a herbal formulation of Zingiber cassumunar and Nigella sativa Prasan Tangyuenyongwatana, Jariya Kowapradit, Praneet Opanasopit, Wandee Gritsanapan Chinese Medicine 2009, 4 :19 (25 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
MALS: an efficient strategy for multiple site-directed mutagenesis employing a combination of DNA amplification, ligation and suppression PCR Alexey A Fushan, Dennis T Drayna BMC Biotechnology 2009, 9 :83 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Mirrors in the PDB: left-handed Srinivas Annavarapu, Vikas Nanda BMC Structural Biology 2009, 9 :61 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Prediction of antigenic epitopes on protein surfaces by consensus scoring Shide Liang, Dandan Zheng, Chi Zhang, Martin Zacharias BMC Bioinformatics 2009, 10 :302 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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