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Protein degradation and cell death Section edited by Patrizia Agostinis

This section will consider submissions on cellular disease mechanisms, protein degradation, autophagy and cell death.

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1.

Research article   Open Access

Respiratory uncoupling by increased H+ or K+ flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition

Saori Morota, Sarah Piel, Magnus J Hansson BMC Cell Biology 2013, 14:40 (22 September 2013)

Abstract | Full text | PDF | PubMed

2.

Methodology article   Open Access

A simple methodology to assess endolysosomal protease activity involved in antigen processing in human primary cells

Archana Vaithilingam, Nicole Y Lai, Ellen Duong, Julie Boucau, Yang Xu, Mariko Shimada, Malini Gandhi, Sylvie Le Gall BMC Cell Biology 2013, 14:35 (9 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

Research article   Open Access

Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis

Matthew Brentnall, Luis Rodriguez-Menocal, Rebeka De Guevara, Enrique Cepero, Lawrence H Boise BMC Cell Biology 2013, 14:32 (9 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

Research article   Open Access

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila

Péter Lőw, Ágnes Varga, Karolina Pircs, Péter Nagy, Zsuzsanna Szatmári, Miklós Sass, Gábor Juhász BMC Cell Biology 2013, 14:29 (25 June 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

When proteasomal degradation is impaired, the Drosophila ortholog of HIF-1α (Hypoxia Induced Factor 1α), sima, contributes to autophagy activation, linking the two main pathways that regulate protein catabolism in eukaryotic cells.

5.

Research article   Open Access

Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153

Seungwoo Kim, Hyo-Soon Cheon, So-Young Kim, Yong-Sung Juhnn, Young-Youl Kim BMC Cell Biology 2013, 14:4 (22 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

GADD153 transcription factor sensitizes cells to reactive oxygen species (ROS) through mechanisms that involve up-regulation of BAK and enhanced oxidant injury in neuroblastoma cells.

6.

Research article   Open Access

Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans

Xiaokun Yu, Junfeng Ma, Feng Lin, Wanke Zhao, Xueqi Fu, Zhizhuang Zhao BMC Cell Biology 2012, 13:28 (31 October 2012)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Phosphorylation of P68 RNA Helicase by P38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin

Heena Dey, Zhi-Ren Liu BMC Cell Biology 2012, 13:27 (31 October 2012)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Unfertilized frog eggs die by apoptosis following meiotic exit

Alexander A Tokmakov, Sho Iguchi, Tetsushi Iwasaki, Yasuo Fukami BMC Cell Biology 2011, 12:56 (23 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

Research article   Open Access

Sirtuin-mediated nuclear differentiation and programmed degradation in Tetrahymena

Kristin M Slade, Sydney Freggiaro, Kyle A Cottrell, Joshua J Smith, Emily A Wiley BMC Cell Biology 2011, 12:40 (21 September 2011)

Abstract | Full text | PDF | PubMed

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