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1.

886
Accesses

Research article   Open Access Highly Accessed

Lipid droplets as ubiquitous fat storage organelles in C. elegans

Shaobing O Zhang, Rhonda Trimble, Fengli Guo, Ho Mak BMC Cell Biology 2010, 11:96 (8 December 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A combination of biochemical, histological and microscopy approaches demonstrates that C. elegans uses lipid droplets as ubiquitous fat storage organelles, with promising implications for the study of fat metabolism in this model organism.

2.

785
Accesses

Review   Open Access Highly Accessed

Circulating microparticles: square the circle

Natasha S Barteneva, Elizaveta Fasler-Kan, Michael Bernimoulin, Joel NH Stern, Eugeny D Ponomarev, Larry Duckett, Ivan A Vorobjev BMC Cell Biology 2013, 14:23 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

534
Accesses

Methodology article   Open Access Highly Accessed

Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue

David Robertson, Kay Savage, Jorge S Reis-Filho, Clare M Isacke BMC Cell Biology 2008, 9:13 (19 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

504
Accesses

Research article   Open Access Highly Accessed

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility

Wenqi Wang, Yang Liu, Kan Liao BMC Cell Biology 2011, 12:49 (13 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

437
Accesses

Research article   Open Access Highly Accessed

Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status

Leticia Basciano, Christophe Nemos, Bernard Foliguet, Natalia de Isla, Marcelo de Carvalho, Nguyen Tran, Ali Dalloul BMC Cell Biology 2011, 12:12 (30 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

436
Accesses

Research article   Open Access

The cell cycle of the planctomycete Gemmata obscuriglobus with respect to cell compartmentalization

Kuo-Chang Lee, Rick I Webb, John A Fuerst BMC Cell Biology 2009, 10:4 (14 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

437
Accesses

Research article   Open Access

Cell metabolism sets the differences between subpopulations of satellite cells (SCs)

Andrea Repele, Ramona Lupi, Simon Eaton, Luca Urbani, Paolo De Coppi, Michelangelo Campanella BMC Cell Biology 2013, 14:24 (3 May 2013)

Abstract | Provisional PDF | PubMed

8.

429
Accesses

Commentary   Open Access Highly Accessed

The MDCK variety pack: choosing the right strain

Joseph D Dukes, Paul Whitley, Andrew D Chalmers BMC Cell Biology 2011, 12:43 (7 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Joseph Dukes and colleagues describe the history and features of the different strains of MDCK (Madin-Darby Canine Kidney) cells, often inadequately reported in the literature, thus providing a useful guide to this widespread epithelial model system.

9.

412
Accesses

Research article   Open Access Highly Accessed

mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging

Rahul B Yadav, Pierre Burgos, Anthony W Parker, Valentina Iadevaia, Christopher G Proud, Rodger A Allen, James P O'Connell, Ananya Jeshtadi, Christopher D Stubbs, Stanley W Botchway BMC Cell Biology 2013, 14:3 (12 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Direct interaction of rapamycin (mTOR) with both Ras homologue enriched in brain (RheB) and regulatory associate protein of mTOR (raptor) identified in living cells using Fluorescence resonance energy transfer–fluorescence lifetime imaging (FRET-FLIM).  

10.

402
Accesses

Methodology article   Open Access Highly Accessed

The CMV early enhancer/chicken β actin (CAG) promoter can be used to drive transgene expression during the differentiation of murine embryonic stem cells into vascular progenitors

Annika N Alexopoulou, John R Couchman, James R Whiteford BMC Cell Biology 2008, 9:2 (11 January 2008)

Abstract | Full text | PDF | PubMed

11.

364
Accesses

Research article   Open Access

H-RN, a peptide derived from hepatocyte growth factor, inhibits corneal neovascularization by inducing endothelial apoptosis and arresting the cell cycle

Ye Sun, Li Su, Zhongxiao Wang, Yi Xu, Xun Xu BMC Cell Biology 2013, 14:8 (24 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A peptide derived from the hepatocyte growth factor kringle 1 domain displays anti-angiogenic activity in HUVEC cells and effectively inhibits VEGF-induced corneal angiogenesis in a mouse model of corneal neovascularization.

12.

359
Accesses

Methodology article   Open Access Highly Accessed

Visualising single molecules of HIV-1 and miRNA nucleic acids

Kate L Jones, Adam Karpala, Bevan Hirst, Kristie Jenkins, Mark Tizard, Cândida F Pereira, Andrew Leis, Paul Monaghan, Alex Hyatt, Johnson Mak BMC Cell Biology 2013, 14:21 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

335
Accesses

Research article   Open Access

Claudins play a role in normal and tumor cell motility

Patricia G Webb, Monique A Spillman, Heidi K Baumgartner BMC Cell Biology 2013, 14:19 (23 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

14.

320
Accesses

Research article   Open Access

Integrin-mediated internalization of Staphylococcus aureus does not require vinculin

Marina Borisova, Yong Shi, Alexander Buntru, Susanne Wörner, Wolfgang H Ziegler, Christof R Hauck BMC Cell Biology 2013, 14:2 (7 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Complementation of vinculin in vinculin-deficient cells, shRNA-mediated knock-down and overexpression in different cell types suggests that vinculin may be insignificant for integrin-mediated internalization of Staphylococcus aureus.

15.

325
Accesses

Research article   Open Access Highly Accessed

Aging of mesenchymal stem cell in vitro

Mandana Bonab, Kamran Alimoghaddam, Fatemeh Talebian, Syed Ghaffari, Ardeshir Ghavamzadeh, Behrouz Nikbin BMC Cell Biology 2006, 7:14 (10 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

314
Accesses

Research article   Open Access Highly Accessed

Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models

Ines Hammami, Jingkui Chen, Frederic Murschel, Vincenzo Bronte, Gregory De Crescenzo, Mario Jolicoeur BMC Cell Biology 2012, 13:18 (4 July 2012)

Abstract | Full text | PDF | PubMed

17.

313
Accesses

Research article   Open Access

Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex

Christoph Kluge, Thorsten Seidel, Susanne Bolte, Shanti S Sharma, Miriam Hanitzsch, Beatrice Satiat-Jeunemaitre, Joachim Roß, Markus Sauer, Dortje Golldack, Karl-Josef Dietz BMC Cell Biology 2004, 5:29 (13 August 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The VHA-a protein is an essential functional, as well as structural, subunit of the vacuolar H+ ATPase of a plant, Mesembryanthemum crytallinum, and is primarily located to the endoplasmic reticulum.

18.

288
Accesses

Research article   Open Access Highly Accessed

Hernia fibroblasts lack β-estradiol induced alterations of collagen gene expression

Petra Jansen, Raphael Rosch, Melanie Rezvani, Peter R Mertens, Karsten Junge, Marc Jansen, Uwe Klinge BMC Cell Biology 2006, 7:36 (29 September 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

280
Accesses

Research article   Open Access

Constant or fluctuating hyperglycemias increases cytomembrane stiffness of human umbilical vein endothelial cells in culture: roles of cytoskeletal rearrangement and nitric oxide synthesis

Xianxian Chen, Lie Feng, Hua Jin BMC Cell Biology 2013, 14:22 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

20.

271
Accesses

Methodology article   Open Access Highly Accessed

Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

Asako Sakaue-Sawano, Tamiyo Kobayashi, Kenji Ohtawa, Atsushi Miyawaki BMC Cell Biology 2011, 12:2 (13 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

271
Accesses

Research article   Open Access

Characterization of adipose-derived stromal/stem cells from the twitcher mouse model of krabbe disease

Xiujuan Zhang, Julie A Semon, Shijia Zhang, Amy L Strong, Brittni A Scruggs, Jeffrey M Gimble, Bruce A Bunnell BMC Cell Biology 2013, 14:20 (16 April 2013)

Abstract | Full text | PDF | PubMed

22.

262
Accesses

Research article   Open Access

Ligands specify estrogen receptor alpha nuclear localization and degradation

Silvia Kocanova, Mahta Mazaheri, Stéphanie Caze-Subra, Kerstin Bystricky BMC Cell Biology 2010, 11:98 (10 December 2010)

Abstract | Full text | PDF | PubMed

23.

254
Accesses

Research article   Open Access Highly Accessed

Anti-proliferative activity of silver nanoparticles

PV AshaRani, M Prakash Hande, Suresh Valiyaveettil BMC Cell Biology 2009, 10:65 (17 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

249
Accesses

Research article   Open Access

Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153

Seungwoo Kim, Hyo-Soon Cheon, So-Young Kim, Yong-Sung Juhnn, Young-Youl Kim BMC Cell Biology 2013, 14:4 (22 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

GADD153 transcription factor sensitizes cells to reactive oxygen species (ROS) through mechanisms that involve up-regulation of BAK and enhanced oxidant injury in neuroblastoma cells.

25.

247
Accesses

Methodology article   Open Access Highly Accessed

3D cell nuclei segmentation based on gradient flow tracking

Gang Li, Tianming Liu, Ashley Tarokh, Jingxin Nie, Lei Guo, Andrew Mara, Scott Holley, Stephen TC Wong BMC Cell Biology 2007, 8:40 (4 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

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