- Patrizia Agostinis, Katholieke Universiteit Leuven
- Anna Akhmanova, Erasmus Medical Center
- Matthias Falk, Lehigh University
- Margarete Goppelt-Struebe, University of Erlangen-Nürnberg
- Andrew Koff, Memorial Sloan-Kettering Cancer Center
- Mark Lemmon, University of Pennsylvania School of Medicine
- Stephen J Royle, University of Liverpool
- Howard J Worman, College of Physicians and Surgeons, Columbia University
- Tim Sands, BioMed Central
All-trans Retinoic Acid (ATRA) is found to have different effects on UCP1 gene expression in human and mouse adipocytes, which may have implications for the treatment of obesity.
Activation of the MEK/ERK signaling pathway is involved in nuclear translocation and G1/S phase transition of human non immortalized intestinal epithelial crypt cells in culture and may be involved in tumour initiation and cell proliferation.
When proteasomal degradation is impaired, the Drosophila ortholog of HIF-1α (Hypoxia Induced Factor 1α), sima, contributes to autophagy activation, linking the two main pathways that regulate protein catabolism in eukaryotic cells.
BMC Cell Biology 2013, 14:54
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