- Anna Akhmanova, Erasmus Medical Center
- Matthias Falk, Lehigh University
- Margarete Goppelt-Struebe, University of Erlangen-Nürnberg
- Xuejun Jiang, Memorial Sloan-Kettering Cancer Center
- Andrew Koff, Memorial Sloan-Kettering Cancer Center
- Mark Lemmon, University of Pennsylvania School of Medicine
- Andrew Peden, University of Sheffield
- Howard J Worman, College of Physicians and Surgeons, Columbia University
- Tim Sands, BioMed Central
Human mesenchymal stem cell-derived adipocytes transfer RNAs into hMSC-derived osteoblasts using extracellular vesicles containing adipogenic genes and anti-osteoblastic micro-RNAs, but additional studies are needed to clarify if this mechanism has a role in the adipocytic switch.
Long-term embryonic stem cell cultures grown in the absence of Leukemia Inhibitory Factor converts multilayered colonies into epistem cell-like monolayers, but in the long term they regain embryonic stem cell-like expression profile of central stem cell markers.
Expression of protein kinase C delta is increased during osteogenesis of human bone marrow derived mesenchymal stem cells (hBMSCs), and its inhibition attenuates osteogenesis and increases lipid accumulation, pointing to a critical role in this balance between osteogenesis and adipogenesis
BMC Cell Biology 2015, 16:13
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