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Translational oncology

This section aims to consider publications which bridge laboratory basic science and applied clinical research. The section will publish studies of diagnostic and prognostic markers which may ultimately be applicable in a clinical setting with a special focus on molecular and experimental pathology. Submissions need to be REMARK compliant as established in NCI-EORTC's "Reporting Recommendations for Tumor Marker Prognostic Studies " (J Clin Oncol 23:9067, 2005) and should report biomarkers that have a clear biologic relevance to a particular tumor type.

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1.

Research article   Open Access

High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

Albrecht Stenzinger, Volker Endris, Frederick Klauschen, Bruno Sinn, Katja Lorenz, Arne Warth, Benjamin Goeppert, Volker Ehemann, Alexander Muckenhuber, Carsten Kamphues, Marcus Bahra, Peter Neuhaus, Wilko Weichert BMC Cancer 2013, 13:450 (2 October 2013)

Abstract | Provisional PDF

2.

Research article   Open Access

High-risk human papillomavirus (HPV) DNA sequences in metaplastic breast carcinomas of Mexican women

Roberto Herrera-Goepfert, Teresa Vela-Chávez, Adela Carrillo-García, Marcela Lizano-Soberón, Alfredo Amador-Molina, Luis F Oñate-Ocaña, Rita Sotelo-Regil Hallmann BMC Cancer 2013, 13:445 (1 October 2013)

Abstract | Provisional PDF

3.

Research article   Open Access

Preoperative neutrophil/lymphocyte ratio predicts overall survival but does not predict recurrence or cancer-specific survival after curative resection of node-positive colorectal cancer

Lucy Jankova, Owen F Dent, Charles Chan, Pierre Chapuis, Stephen J Clarke BMC Cancer 2013, 13:442 (1 October 2013)

Abstract | Provisional PDF

4.

Research article   Open Access

Expression of activator protein-1 (AP-1) family members in breast cancer

Amirhossein Kharman-Biz, Hui Gao, Reza Ghiasvand, Chunyan Zhao, Kazem Zendehdel, Karin Dahlman-Wright BMC Cancer 2013, 13:441 (28 September 2013)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

Vlad Popovici, Eva Budinska, Fred T Bosman, Sabine Tejpar, Arnaud D Roth, Mauro Delorenzi BMC Cancer 2013, 13:439 (27 September 2013)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access

The presence of tumour-associated lymphocytes confers a good prognosis in pancreatic ductal adenocarcinoma: an immunohistochemical study of tissue microarrays

Nilanjana Tewari, Abed M Zaitoun, Arvind Arora, Srinivasan Madhusudan, Mohammad Ilyas, Dileep N Lobo BMC Cancer 2013, 13:436 (24 September 2013)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Class III beta-tubulin is a predictive marker for taxane-based chemotherapy in recurrent and metastatic gastric cancer

Jun-Eul Hwang, Ji-Yun Hong, Karham Kim, Seung-Hun Kim, Won-Young Choi, Min-Jee Kim, Sung-Hoon Jung, Hyun-Jeong Shim, Woo-Kyun Bae, Eu-Chang Hwang, Kyung-Hwa Lee, Jae-Hyuk Lee, Sang-Hee Cho, Ik-Joo Chung BMC Cancer 2013, 13:431 (23 September 2013)

Abstract | Provisional PDF | PubMed

8.

Research article   Open Access

Intestinal-type of differentiation predicts favourable overall survival: confirmatory clinicopathological analysis of 198 periampullary adenocarcinomas of pancreatic, biliary, ampullary and duodenal origin

Peter Bronsert, Ilona Kohler, Martin Werner, Frank Makowiec, Simon Kuesters, Jens Hoeppner, Ulrich Hopt, Tobias Keck, Dirk Bausch, Ulrich Wellner BMC Cancer 2013, 13:428 (22 September 2013)

Abstract | Full text | PDF | PubMed

9.

Technical advance   Open Access

Method validation of circulating tumour cell enumeration at low cell counts

Jeffrey Cummings, Karen Morris, Cong Zhou, Robert Sloane, Matt Lancashire, Daniel Morris, Stephen Bramley, Matt Krebs, Leila Khoja, Caroline Dive BMC Cancer 2013, 13:415 (11 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research article   Open Access

ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma

Masaki Nagata, Arhab A Noman, Kenji Suzuki, Hiroshi Kurita, Makoto Ohnishi, Tokio Ohyama, Nobutaka Kitamura, Takanori Kobayashi, Kohya Uematsu, Katsu Takahashi, Naoki Kodama, Tomoyuki Kawase, Hideyuki Hoshina, Nobuyuki Ikeda, Susumu Shingaki, Ritsuo Takagi BMC Cancer 2013, 13:410 (5 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

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