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Clinical and radiation oncology

This section focuses on all aspects of clinical oncology. This includes research that impacts on the treatment of cancer using chemotherapy and radiation. Results of randomized controlled trials are particularly welcomed.

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1.

Research article   Open Access

Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial

Maria Teresa Solomó, Julio César Selva, Javier Figueredo, José Vaquer, Carolina Toledo, Nelson Quintanal, Silvia Salva, Rafael Domíngez, José Alert, Jorge Juan Marinello, Mauricio Catalá, Martha González Griego, Juan Antonio Martell, Patricia Lorenzo Luaces, Javier Ballesteros, Niurys de-Castro, Ferdinand Bach, Tania Crombet BMC Cancer 2013, 13:299 (19 June 2013)

Abstract | Provisional PDF

2.

Study protocol   Open Access

CATCH: a randomised clinical trial comparing long-term tinzaparin versus warfarin for treatment of acute venous thromboembolism in cancer patients

Agnes YY Lee, Rupert Bauersachs, Mette S Janas, Mikala F Jarner, Pieter W Kamphuisen, Guy Meyer, Alok A Khorana BMC Cancer 2013, 13:284 (13 June 2013)

Abstract | Provisional PDF | PubMed

3.

Study protocol   Open Access

Phase II/III multicentre randomised controlled trial evaluating a strategy of primary surgery and adjuvant chemotherapy versus peri-operative chemotherapy for resectable gastric signet ring cell adenocarcinomas -- PRODIGE 19 -- FFCD1103 -- ADCI002

Guillaume Piessen, Mathieu Messager, Karine Le Malicot, William B Robb, Frédéric Di Fiore, Marie Guilbert, Marie Moreau, Véronique Christophe, Antoine Adenis, Christophe Mariette BMC Cancer 2013, 13:281 (10 June 2013)

Abstract | Provisional PDF | PubMed

4.

Study protocol   Open Access

Short-course radiotherapy followed by neo-adjuvant chemotherapy in locally advanced rectal cancer – the RAPIDO trial

Per J Nilsson, Boudewijn van Etten, Geke AP Hospers, Lars Påhlman, Cornelis JH van de Velde, Regina GH Beets-Tan, Lennart Blomqvist, Jannet C Beukema, Ellen Kapiteijn, Corrie AM Marijnen, Iris D Nagtegaal, Theo Wiggers, Bengt Glimelius BMC Cancer 2013, 13:279 (7 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research article   Open Access

Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases

Marieke WJLAE Wertenbroek, Marianne Schepers, Hannetta J Kamminga-Rasker, Jan T Bottema, Anneke C Muller Kobold, Han Roelofsen, Koert P de Jong BMC Cancer 2013, 13:266 (30 May 2013)

Abstract | Provisional PDF | PubMed

6.

Research article   Open Access

Dose selection trial of metronomic oral vinorelbine monotherapy in patients with metastatic cancer: a hellenic cooperative oncology group clinical translational study

Evangelos Briasoulis, Gerasimos Aravantinos, George Kouvatseas, Periklis Pappas, Eirini Biziota, Ioannis Sainis, Thomas Makatsoris, Ioannis Varthalitis, Ioannis Xanthakis, Antonios Vassias, George Klouvas, Ioannis Boukovinas, George Fountzilas, Kostantinos N Syrigos, Haralambos Kalofonos, Epaminontas Samantas BMC Cancer 2013, 13:263 (29 May 2013)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central

7.

Case report   Open Access Highly Accessed

Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4–ALK-rearranged non–small–cell lung cancer harbored coexisting EGFR mutation

Akihiko Miyanaga, Kumi Shimizu, Rintaro Noro, Masahiro Seike, Kazuhiro Kitamura, Seiji Kosaihira, Yuji Minegishi, Takehito Shukuya, Akinobu Yoshimura, Masashi Kawamoto, Shinichi Tsuchiya, Koichi Hagiwara, Manabu Soda, Kengo Takeuchi, Nobuyuki Yamamoto, Hiroyuki Mano, Yuichi Ishikawa, Akihiko Gemma BMC Cancer 2013, 13:262 (29 May 2013)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma

Shao-Bo Liang, Yan-Ming Deng, Ning Zhang, Rui-Liang Lu, Hai Zhao, Hai-Yang Chen, Shao-En Li, Dong-Sheng Liu, Yong Chen BMC Cancer 2013, 13:260 (27 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

Research article   Open Access

Nuclear TK1 expression is an independent prognostic factor for survival in pre-malignant and malignant lesions of the cervix

Gang Chen, Cheng He, Ling Li, An Lin, Xiongwei Zheng, Ellen He, Sven Skog BMC Cancer 2013, 13:249 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research article   Open Access

Neoadjuvant rh-endostatin, docetaxel and epirubicin for breast cancer: efficacy and safety in a prospective, randomized, phase II study

Jianghao Chen, Qing Yao, Dong Li, Juliang Zhang, Ting Wang, Ming Yu, Xiaodong Zhou, Yi Huan, Jing Wang, Ling Wang BMC Cancer 2013, 13:248 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

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