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Cell and molecular biology

This section covers all aspects of tumor biology from a molecular and cellular point of view. Topics of interest include, but are not limited to, animal models, hypoxia, angiogenesis, metastasis, cellular signaling, cancer stem cells, DNA damage and repair, cell cycle and apoptosis.

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1.

Research article   Open Access

The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma

Qi Zhou, Yafeng Wang, Baogang Peng, Lijian Liang, Jiaping Li BMC Cancer 2013, 13:244 (20 May 2013)

Abstract | Provisional PDF

2.

Research article   Open Access

Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells

Emelie Karnevi, Katarzyna Said, Roland Andersson, Ann H Rosendahl BMC Cancer 2013, 13:235 (10 May 2013)

Abstract | Provisional PDF | PubMed

3.

Research article   Open Access

Cisplatin-induced caspase activation mediates PTEN cleavage in ovarian cancer cells: a potential mechanism of chemoresistance

Mohan Singh, Parvesh Chaudhry, Francois Fabi, Eric Asselin BMC Cancer 2013, 13:233 (10 May 2013)

Abstract | Provisional PDF | PubMed

4.

Research article   Open Access

Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

James S Foster, Lindsay M Fish, Jonathan E Phipps, Charles T Bruker, James M Lewis, John L Bell, Alan Solomon, Daniel P Kestler BMC Cancer 2013, 13:227 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research article   Open Access Highly Accessed

Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors

Kirsten Ludwig, Edison S Tse, Jean YJ Wang BMC Cancer 2013, 13:221 (2 May 2013)

Abstract | Provisional PDF | PubMed

6.

Research article   Open Access

VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma

Bharat K Majeti, Joseph H Lee, Brett H Simmons, Farbod Shojaei BMC Cancer 2013, 13:213 (29 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

Research article   Open Access

Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis

Zhongsheng Peng, Jonathon Heath, Cinthia Drachenberg, Jean-Pierre Raufman, Guofeng Xie BMC Cancer 2013, 13:204 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

Research article   Open Access

JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1

Xia Zhan, Xiaobing Feng, Ying Kong, Yi Chen, Wenfu Tan BMC Cancer 2013, 13:180 (4 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

Research article   Open Access

Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities

Christian Marfels, Miriam Hoehn, Ernst Wagner, Michael Günther BMC Cancer 2013, 13:176 (2 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research article   Open Access Highly Accessed

The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer

Yan Ni Loh, Ellen L Hedditch, Laura A Baker, Eve Jary, Robyn L Ward, Caroline E Ford BMC Cancer 2013, 13:174 (2 April 2013)

Abstract | Full text | PDF | PubMed

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