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51.

445
Accesses

Research article   Open Access

Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

James S Foster, Lindsay M Fish, Jonathan E Phipps, Charles T Bruker, James M Lewis, John L Bell, Alan Solomon, Daniel P Kestler BMC Cancer 2013, 13:227 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

52.

440
Accesses

Research article   Open Access Highly Accessed

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

Andrea Köhrmann, Ulrike Kammerer, Michaela Kapp, Johannes Dietl, Jelena Anacker BMC Cancer 2009, 9:188 (16 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

53.

438
Accesses

Research article   Open Access Highly Accessed

Genome-wide expression patterns associated with oncogenesis and sarcomatous transdifferentation of cholangiocarcinoma

Min-A Seol, In-Sun Chu, Mi-Jin Lee, Goung-Ran Yu, Xiang-Dan Cui, Baik-Hwan Cho, Eun-Kyung Ahn, Sun-Hee Leem, In-Hee Kim, Dae-Ghon Kim BMC Cancer 2011, 11:78 (19 February 2011)

Abstract | Full text | PDF | PubMed

54.

436
Accesses

Case report   Open Access Highly Accessed

Primary pancreatic lymphoma – pancreatic tumours that are potentially curable without resection, a retrospective review of four cases

Peter S Grimison, Melvin T Chin, Michelle L Harrison, David Goldstein BMC Cancer 2006, 6:117 (4 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

55.

418
Accesses

Study protocol   Open Access Highly Accessed

Conquer fear: protocol of a randomised controlled trial of a psychological intervention to reduce fear of cancer recurrence

Phyllis N Butow, Melanie L Bell, Allan B Smith, Joanna E Fardell, Belinda Thewes, Jane Turner, Jemma Gilchrist, Jane Beith, Afaf Girgis, Louise Sharpe, Sophy Shih, Cathrine Mihalopoulos, members of the Conquer Fear Authorship Group BMC Cancer 2013, 13:201 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

56.

414
Accesses

Research article   Open Access Highly Accessed

Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

Olfa Derbel, Qing Wang, Françoise Desseigne, Michel Rivoire, Pierre Meeus, Patrice Peyrat, Mattia Stella, Isabelle Martel-Lafay, Anne-Isabelle Lemaistre, Christelle de La Fouchardière BMC Cancer 2013, 13:200 (23 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

57.

418
Accesses

Research article   Open Access Highly Accessed

Magnetic resonance imaging for lung cancer detection: Experience in a population of more than 10,000 healthy individuals

Nai-Yuan Wu, Hui-Cheng Cheng, James S Ko, Yu-Chen Cheng, Po-Wei Lin, Wei-Chan Lin, Cheng-Yen Chang, Der-Ming Liou BMC Cancer 2011, 11:242 (13 June 2011)

Abstract | Full text | PDF | PubMed

58.

411
Accesses

Technical advance   Open Access

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Hee-Sheung Lee, Nicholas CO Lee, Brenda R Grimes, Alexander Samoshkin, Artem V Kononenko, Ruchi Bansal, Hiroshi Masumoto, William C Earnshaw, Natalay Kouprina, Vladimir Larionov BMC Cancer 2013, 13:252 (22 May 2013)

Abstract | Provisional PDF | PubMed

59.

405
Accesses

Research article   Open Access Highly Accessed

PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells

Hao Liu, Abdul Qader Omer Al-aidaroos, Haihe Wang, Ke Guo, Jie Li, Hua Fei Zhang, Qi Zeng BMC Cancer 2013, 13:80 (18 February 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The protein tyrosine phosphatase PRL-3 (Phosphatase of Regenerating Liver-3) is highly expressed in human ovarian cancer patient samples and may promote cancer cell migration, invasion and metastasis via inhibition of c-fos transcriptional regulation of integrin alpha2 signaling.

60.

398
Accesses

Research article   Open Access Highly Accessed

Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator

Philip Vlaicu, Philipp Mertins, Thomas Mayr, Peter Widschwendter, Beyhan Ataseven, Bernhard Högel, Wolfgang Eiermann, Pjotr Knyazev, Axel Ullrich BMC Cancer 2013, 13:197 (18 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

61.

400
Accesses

Research article   Open Access

Age dependence of tumor genetics in unfavorable neuroblastoma: arrayCGH profiles of 34 consecutive cases, using a Swedish 25-year neuroblastoma cohort for validation

Cihan Cetinkaya, Tommy Martinsson, Johanna Sandgren, Catarina Träger, Per Kogner, Jan Dumanski, Teresita Díaz de Ståhl, Fredrik Hedborg BMC Cancer 2013, 13:231 (9 May 2013)

Abstract | Full text | PDF | PubMed

62.

393
Accesses

Review   Open Access Highly Accessed

Functional significance of erythropoietin in renal cell carcinoma

Christudas Morais, David W Johnson, David A Vesey, Glenda C Gobe BMC Cancer 2013, 13:14 (10 January 2013)

Abstract | Full text | PDF | PubMed

63.

391
Accesses

Research article   Open Access

Anti-cancer effects of newly developed chemotherapeutic agent, glycoconjugated palladium (II) complex, against cisplatin-resistant gastric cancer cells

Mamoru Tanaka, Hiromi Kataoka, Shigenobu Yano, Hiromi Ohi, Keisuke Kawamoto, Takashi Shibahara, Tsutomu Mizoshita, Yoshinori Mori, Satoshi Tanida, Takeshi Kamiya, Takashi Joh BMC Cancer 2013, 13:237 (14 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

64.

390
Accesses

Research article   Open Access Highly Accessed

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway

Daniel Habermehl, Bernd Kammerer, René Handrick, Therese Eldh, Charlotte Gruber, Nils Cordes, Peter T Daniel, Ludwig Plasswilm, Michael Bamberg, Claus Belka, Verena Jendrossek BMC Cancer 2006, 6:14 (17 January 2006)

Abstract | Full text | PDF | PubMed

65.

381
Accesses

Research article   Open Access

MicroRNA profile of paclitaxel-resistant serous ovarian carcinoma based on formalin-fixed paraffin-embedded samples

Xiao Li, Yaer Lu, Yaxia Chen, Weiguo Lu, Xing Xie BMC Cancer 2013, 13:216 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

66.

380
Accesses

Research article   Open Access

Prognostic significance of peripheral monocyte count in patients with extranodal natural killer/T-cell lymphoma

Jia-Jia Huang, Ya-Jun Li, Yi Xia, Yu Wang, Wen-Xiao Wei, Ying-Jie Zhu, Tong-Yu Lin, Hui-Qiang Huang, Wen-Qi Jiang, Zhi-Ming Li BMC Cancer 2013, 13:222 (3 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

67.

378
Accesses

Research article   Open Access

Genetic variation in TLR or NFkappaB pathways and the risk of breast cancer: a case-control study

Alexa J Resler, Kathleen E Malone, Lisa G Johnson, Mari Malkki, Effie W Petersdorf, Barbara McKnight, Margaret M Madeleine BMC Cancer 2013, 13:219 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

68.

377
Accesses

Research article   Open Access

Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model

Tao Hu, Chunhua Zhang, Qiongling Tang, Yanan Su, Bo Li, Long Chen, Zheng Zhang, Tianchi Cai, Yuechun Zhu BMC Cancer 2013, 13:251 (22 May 2013)

Abstract | Provisional PDF | PubMed

69.

373
Accesses

Research article   Open Access Highly Accessed

Steroid hormone receptor expression in ovarian cancer: progesterone receptor B as prognostic marker for patient survival

Miriam Lenhard, Lennerová Tereza, Sabine Heublein, Nina Ditsch, Isabelle Himsl, Doris Mayr, Klaus Friese, Udo Jeschke BMC Cancer 2012, 12:553 (24 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Estrogen receptors ER-alpha/-beta and progesterone receptors PR-A/-B are frequently expressed in ovarian cancer with a certain variability relating to histological subtype, grade and stage; and multivariate analysis suggests that PR-B is an independent prognostic marker for patient survival.

70.

368
Accesses

Research article   Open Access

Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma

Chiharu Tabata, Eisuke Shibata, Rie Tabata, Shingo Kanemura, Koji Mikami, Yoshitaka Nogi, Eriko Masachika, Tomoyuki Nishizaki, Takashi Nakano BMC Cancer 2013, 13:205 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

71.

367
Accesses

Research article   Open Access

Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemotherapy

Mamoru Takada, Toru Higuchi, Katsunori Tozuka, Hiroyuki Takei, Masayuki Haruta, Junko Watanabe, Fumio Kasai, Kenichi Inoue, Masafumi Kurosumi, Masaru Miyazaki, Aiko Sato-Otsubo, Seishi Ogawa, Yasuhiko Kaneko BMC Cancer 2013, 13:241 (16 May 2013)

Abstract | Full text | PDF | PubMed

72.

363
Accesses

Research article   Open Access

Correlation of CD44v6 expression with ovarian cancer progression and recurrence

Jun Shi, Zhou Zhou, Wen Di, Ningli Li BMC Cancer 2013, 13:182 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

73.

361
Accesses

Research article   Open Access Highly Accessed

Diagnostic value of fine-needle aspiration biopsy for breast mass: a systematic review and meta-analysis

Ying-Hua Yu, Wei Wei, Jian-Lun Liu BMC Cancer 2012, 12:41 (25 January 2012)

Abstract | Full text | PDF | PubMed

74.

362
Accesses

Research article   Open Access Highly Accessed

Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

Ho-Keun Kwon, Ji-Sun Hwang, Jae-Seon So, Choong-Gu Lee, Anupama Sahoo, Jae-Ha Ryu, Won Jeon, Byoung Ko, Chang-Rok Im, Sung Lee, Zee Park, Sin-Hyeog Im BMC Cancer 2010, 10:392 (24 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

75.

354
Accesses

Research article   Open Access Highly Accessed

Quality of life in patients with breast cancer before and after diagnosis: an eighteen months follow-up study

Ali Montazeri, Mariam Vahdaninia, Iraj Harirchi, Mandana Ebrahimi, Fatemeh Khaleghi, Soghra Jarvandi BMC Cancer 2008, 8:330 (11 November 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

76.

348
Accesses

Research article   Open Access Highly Accessed

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

Catharina Medrek, Fredrik Pontén, Karin Jirström, Karin Leandersson BMC Cancer 2012, 12:306 (23 July 2012)

Abstract | Full text | PDF | PubMed

77.

348
Accesses

Research article   Open Access

Alteration of gene expression profiles during mycoplasma-induced malignant cell transformation

Shimin Zhang, Shien Tsai, Shyh-Ching Lo BMC Cancer 2006, 6:116 (4 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

348
Accesses

Research article   Open Access Highly Accessed

Hypoxic enhancement of exosome release by breast cancer cells

Hamish W King, Michael Z Michael, Jonathan M Gleadle BMC Cancer 2012, 12:421 (24 September 2012)

Abstract | Full text | PDF | PubMed

79.

347
Accesses

Research article   Open Access Highly Accessed

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

Junliang Ma, Lunxu Liu, Guowei Che, Nanbin Yu, Fuqiang Dai, Zongbing You BMC Cancer 2010, 10:112 (25 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

80.

341
Accesses

Technical advance   Open Access

Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection

Giada V Zapparoli, Robert N Jorissen, Chelsee A Hewitt, Michelle McBean, David A Westerman, Alexander Dobrovic BMC Cancer 2013, 13:206 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

81.

344
Accesses

Research article   Open Access

Characteristic mTOR activity in Hodgkin-lymphomas offers a potential therapeutic target in high risk disease -- a combined tissue microarray, in vitro and in vivo study

Ágnes Márk, Melinda Hajdu, Zsófia Váradi, Tamás Béla Sticz, Noémi Nagy, Judit Csomor, Lajos Berczi, Viktória Varga, Monika Csóka, László Kopper, Anna Sebestyén BMC Cancer 2013, 13:250 (22 May 2013)

Abstract | Provisional PDF | PubMed

82.

339
Accesses

Research article   Open Access Highly Accessed

The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer

Yan Ni Loh, Ellen L Hedditch, Laura A Baker, Eve Jary, Robyn L Ward, Caroline E Ford BMC Cancer 2013, 13:174 (2 April 2013)

Abstract | Full text | PDF | PubMed

83.

337
Accesses

Research article   Open Access Highly Accessed

Nottingham Prognostic Index in Triple-Negative Breast Cancer: a reliable prognostic tool?

André Albergaria, Sara Ricardo, Fernanda Milanezi, Vítor Carneiro, Isabel Amendoeira, Daniella Vieira, Jorge Cameselle-Teijeiro, Fernando Schmitt BMC Cancer 2011, 11:299 (15 July 2011)

Abstract | Full text | PDF | PubMed

84.

337
Accesses

Research article   Open Access Highly Accessed

Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression

Xinlan Fan, Xu Chen, Weixi Deng, Guangzheng Zhong, Qingqing Cai, Tianxin Lin BMC Cancer 2013, 13:61 (5 February 2013)

Abstract | Full text | PDF | PubMed

85.

331
Accesses

Study protocol   Open Access

Preoperative chemosensitivity testing as Predictor of Treatment benefit in Adjuvant stage III colon cancer (PePiTA): Protocol of a prospective BGDO (Belgian Group for Digestive Oncology) multicentric study

Alain Hendlisz, Vassilis Golfinopoulos, Amelie Deleporte, Marianne Paesmans, Hazem El Mansy, Camilo Garcia, Marc Peeters, Lieven Annemans, Caroline Vandeputte, Marion Maetens, Ivan Borbath, Damien Dresse, Ghislain Houbiers, Michael Fried, Ahmad Awada, Martine Piccart, Jean-Luc Van Laethem, Patrick Flamen BMC Cancer 2013, 13:190 (12 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

86.

335
Accesses

Research article   Open Access

Association between delayed initiation of adjuvant CMF or anthracycline-based chemotherapy and survival in breast cancer: a systematic review and meta-analysis

Ke-Da Yu, Sheng Huang, Jia-Xin Zhang, Guang-Yu Liu, Zhi-Ming Shao BMC Cancer 2013, 13:240 (16 May 2013)

Abstract | Provisional PDF | PubMed

87.

334
Accesses

Research article   Open Access Highly Accessed

Identification of a biomarker panel for colorectal cancer diagnosis

Amaia García-Bilbao, Rubén Armañanzas, Ziortza Ispizua, Begoña Calvo, Ana Alonso-Varona, Iñaki Inza, Pedro Larrañaga, Guillermo López-Vivanco, Blanca Suárez-Merino, Mónica Betanzos BMC Cancer 2012, 12:43 (26 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

88.

334
Accesses

Research article   Open Access Highly Accessed

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

Alexandria M Haslehurst, Madhuri Koti, Moyez Dharsee, Paulo Nuin, Ken Evans, Joseph Geraci, Timothy Childs, Jian Chen, Jieran Li, Johanne Weberpals, Scott Davey, Jeremy Squire, Paul C Park, Harriet Feilotter BMC Cancer 2012, 12:91 (19 March 2012)

Abstract | Full text | PDF | PubMed

89.

334
Accesses

Research article   Open Access Highly Accessed

Patterns of regional lymph node metastasis of nasopharyngeal carcinoma: A meta-analysis of clinical evidence

Francis CH Ho, Ivan WK Tham, Arul Earnest, Khai Lee, Jiade J Lu BMC Cancer 2012, 12:98 (21 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

90.

332
Accesses

Research article   Open Access Highly Accessed

Differences in integrin expression and signaling within human breast cancer cells

Aliakbar Taherian, Xinlei Li, Yongqing Liu, Thomas A Haas BMC Cancer 2011, 11:293 (13 July 2011)

Abstract | Full text | PDF | PubMed

91.

329
Accesses

Review   Open Access Highly Accessed

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

Vasilis P Androutsopoulos, Aristidis M Tsatsakis, Demetrios A Spandidos BMC Cancer 2009, 9:187 (16 June 2009)

Abstract | Full text | PDF | PubMed

92.

324
Accesses

Research article   Open Access Highly Accessed

Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process

Uma R Chandran, Changqing Ma, Rajiv Dhir, Michelle Bisceglia, Maureen Lyons-Weiler, Wenjing Liang, George Michalopoulos, Michael Becich, Federico A Monzon BMC Cancer 2007, 7:64 (12 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

93.

322
Accesses

Research article   Open Access

A novel IgE antibody targeting the prostate-specific antigen as a potential prostate cancer therapy

Tracy R Daniels-Wells, Gustavo Helguera, Richard K Leuchter, Rafaela Quintero, Maggie Kozman, José A Rodríguez, Elizabeth Ortiz-Sánchez, Otoniel Martínez-Maza, Birgit C Schultes, Christopher F Nicodemus, Manuel L Penichet BMC Cancer 2013, 13:195 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

94.

316
Accesses

Study protocol   Open Access Highly Accessed

Manual lymphatic drainage therapy in patients with breast cancer related lymphoedema

Marta Martín, Miguel A Hernández, Cristina Avendaño, Francisco Rodríguez, Helena Martínez BMC Cancer 2011, 11:94 (9 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

95.

318
Accesses

Research article   Open Access Highly Accessed

Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells

Eduardo C Filippi-Chiela, Marcos Paulo Thomé, Mardja Manssur Bueno e Silva, Alessandra Luíza Pelegrini, Pitia Flores Ledur, Bernardo Garicochea, Lauren L Zamin, Guido Lenz BMC Cancer 2013, 13:147 (22 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

96.

315
Accesses

Research article   Open Access Highly Accessed

Early detection of breast cancer: benefits and risks of supplemental breast ultrasound in asymptomatic women with mammographically dense breast tissue. A systematic review

Monika Nothacker, Volker Duda, Markus Hahn, Mathias Warm, Friedrich Degenhardt, Helmut Madjar, Susanne Weinbrenner, Ute-Susann Albert BMC Cancer 2009, 9:335 (20 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

97.

309
Accesses

Research article   Open Access Highly Accessed

In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells

Drazen B Zimonjic, Lai N Chan, Veenu Tripathi, Jie Lu, Ohyun Kwon, Nicholas C Popescu, Douglas R Lowy, Fuyuhiko Tamanoi BMC Cancer 2013, 13:198 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

98.

308
Accesses

Review   Open Access Highly Accessed

Kaposi sarcoma in unusual locations

Liron Pantanowitz, Bruce J Dezube BMC Cancer 2008, 8:190 (7 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

99.

304
Accesses

Research article   Open Access

Detection of antibodies directed at M. hyorhinis p37 in the serum of men with newly diagnosed prostate cancer

Cydney Urbanek, Steve Goodison, Myron Chang, Stacy Porvasnik, Noburo Sakamoto, Chen-zhong Li, Susan K Boehlein, Charles J Rosser BMC Cancer 2011, 11:233 (10 June 2011)

Abstract | Full text | PDF | PubMed

100.

305
Accesses

Research article   Open Access

Evaluation of hypoxia in a feline model of head and neck cancer using 64Cu-ATSM positron emission tomography/computed tomography

Elizabeth A Ballegeer, Nicole J Madrill, Kevin L Berger, Dalen W Agnew, Elizabeth A McNiel BMC Cancer 2013, 13:218 (30 April 2013)

Abstract | Provisional PDF | PubMed

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