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1.

10000
Accesses

Research article   Open Access Highly Accessed

Secular trends of salted fish consumption and nasopharyngeal carcinoma: a multi-jurisdiction ecological study in 8 regions from 3 continents

Hiu-Ying Lau, Chit-Ming Leung, Yap-Hang Chan, Anne Wing-Mui Lee, Dora Lai-Wan Kwong, Maria Lung, Tai-Hing Lam BMC Cancer 2013, 13:298 (19 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

3031
Accesses

Review   Open Access Highly Accessed

Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment

Marlies E Heuvers, Joachim G Aerts, Robin Cornelissen, Harry Groen, Henk C Hoogsteden, Joost P Hegmans BMC Cancer 2012, 12:580 (5 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

2845
Accesses

Study protocol   Open Access Highly Accessed

A randomized, phase III trial of capecitabine plus bevacizumab (Cape-Bev) versus capecitabine plus irinotecan plus bevacizumab (CAPIRI-Bev) in first-line treatment of metastatic colorectal cancer: The AIO KRK 0110 Trial/ML22011 Trial

Clemens Giessen, Ludwig von Weikersthal, Axel Hinke, Sebastian Stintzing, Frank Kullmann, Ursula Vehling-Kaiser, Julia Mayerle, Markus Bangerter, Claudio Denzlinger, Markus Sieber, Christian Teschendorf, Jens Freiberg-Richter, Christoph Schulz, Dominik Modest, Nicolas Moosmann, Philipp Aubele, Volker Heinemann BMC Cancer 2011, 11:367 (23 August 2011)

Abstract | Full text | PDF | PubMed

4.

1894
Accesses

Technical advance   Open Access Highly Accessed

Simultaneous identification of 36 mutations in KRAS codons 61and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit

Hideaki Bando, Takayuki Yoshino, Eiji Shinozaki, Tomohiro Nishina, Kentaro Yamazaki, Kensei Yamaguchi, Satoshi Yuki, Shinya Kajiura, Satoshi Fujii, Takeharu Yamanaka, Katsuya Tsuchihara, Atsushi Ohtsu BMC Cancer 2013, 13:405 (3 September 2013)

Abstract | Full text | PDF | PubMed

5.

1472
Accesses

Research article   Open Access

Different regression equations relate age to the incidence of Lauren types 1 and 2 stomach cancer in the SEER database: these equations are unaffected by sex or race

Mitchell S Wachtel, Yan Zhang, Maurizio Chiriva-Internati, Eldo E Frezza BMC Cancer 2006, 6:65 (15 March 2006)

Abstract | Full text | PDF | PubMed

6.

1425
Accesses

Research article   Open Access Highly Accessed

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion

Takaya Shimura, Michihiro Yoshida, Shinji Fukuda, Masahide Ebi, Yoshikazu Hirata, Tsutomu Mizoshita, Satoshi Tanida, Hiromi Kataoka, Takeshi Kamiya, Shigeki Higashiyama, Takashi Joh BMC Cancer 2012, 12:205 (30 May 2012)

Abstract | Full text | PDF | PubMed

7.

1407
Accesses

Research article   Open Access Highly Accessed

Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process

Uma R Chandran, Changqing Ma, Rajiv Dhir, Michelle Bisceglia, Maureen Lyons-Weiler, Wenjing Liang, George Michalopoulos, Michael Becich, Federico A Monzon BMC Cancer 2007, 7:64 (12 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

1404
Accesses

Research article   Open Access Highly Accessed

Id2 promotes the invasive growth of MCF-7 and SKOV-3 cells by a novel mechanism independent of dimerization to basic helix-loop-helix factors

Yuanguang Meng, Chenglei Gu, Zhiqiang Wu, Yali Zhao, Yiling Si, Xiaobing Fu, Weidong Han BMC Cancer 2009, 9:75 (4 March 2009)

Abstract | Full text | PDF | PubMed

9.

1268
Accesses

Research article   Open Access

Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer

Florian R Fritzsche, Wilko Weichert, Annika Röske, Volker Gekeler, Thomas Beckers, Carsten Stephan, Klaus Jung, Katharina Scholman, Carsten Denkert, Manfred Dietel, Glen Kristiansen BMC Cancer 2008, 8:381 (19 December 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

1101
Accesses

Research article   Open Access Highly Accessed

Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

Reinhold Wasserkort, Alexandra Kalmar, Gabor Valcz, Sandor Spisak, Manuel Krispin, Kinga Toth, Zsolt Tulassay, Andrew Z Sledziewski, Bela Molnar BMC Cancer 2013, 13:398 (30 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

1099
Accesses

Research article   Open Access Highly Accessed

Classical homeopathy in the treatment of cancer patients - a prospective observational study of two independent cohorts

Matthias Rostock, Johannes Naumann, Corina Guethlin, Lars Guenther, Hans H Bartsch, Harald Walach BMC Cancer 2011, 11:19 (17 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments

12.

932
Accesses

Research article   Open Access Highly Accessed

Metabolic system alterations in pancreatic cancer patient serum: potential for early detection

Shawn A Ritchie, Hirofumi Akita, Ichiro Takemasa, Hidetoshi Eguchi, Elodie Pastural, Hiroaki Nagano, Morito Monden, Yuichiro Doki, Masaki Mori, Wei Jin, Tolulope T Sajobi, Dushmanthi Jayasinghe, Bassirou Chitou, Yasuyo Yamazaki, Thayer White, Dayan B Goodenowe BMC Cancer 2013, 13:416 (12 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

879
Accesses

Research article   Open Access Highly Accessed

Cancer odor in the blood of ovarian cancer patients: a retrospective study of detection by dogs during treatment, 3 and 6 months afterward

György Horvath, Håkan Andersson, Szilárd Nemes BMC Cancer 2013, 13:396 (26 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

14.

876
Accesses

Research article   Open Access Highly Accessed

Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts

Sherrill L Macura, Jeremy L Steinbacher, Maximilian B MacPherson, Melissa J Lathrop, Mutlay Sayan, Jedd M Hillegass, Stacie L Beuschel, Timothy N Perkins, Page C Spiess, Albert van der Vliet, Kelly J Butnor, Arti Shukla, Marilyn Wadsworth, Christopher C Landry, Brooke T Mossman BMC Cancer 2013, 13:400 (11 September 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Silica microparticles loaded with doxorubicin (DOX) and modified with a mesothelin specific antibody demonstrate higher effectiveness and lower toxicity than DOX systemic treatment in a mouse xenograft model of human peritoneal mesothelioma.

15.

813
Accesses

Research article   Open Access Highly Accessed

HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop

Zanobia A Syed, Weihong Yin, Kendall Hughes, Jennifer N Gill, Runhua Shi, John L Clifford BMC Cancer 2011, 11:180 (19 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

810
Accesses

Technical advance   Open Access Highly Accessed

Automatic registration of multi-modal microscopy images for integrative analysis of prostate tissue sections

Giuseppe Lippolis, Anders Edsjö, Leszek Helczynski, Anders Bjartell, Niels Overgaard BMC Cancer 2013, 13:408 (5 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

807
Accesses

Research article   Open Access Highly Accessed

Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells

Xinfeng Yu, Xuemei Zhang, Ishwori B Dhakal, Marjorie Beggs, Susan Kadlubar, Dali Luo BMC Cancer 2012, 12:29 (20 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

802
Accesses

Research article   Open Access Highly Accessed

Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells

Seth W Perry, Jill M Schueckler, Kathleen Burke, Giuseppe L Arcuri, Edward B Brown BMC Cancer 2013, 13:411 (5 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

763
Accesses

Research article   Open Access Highly Accessed

Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer

Xing-Hua Liang, Ling-ling Li, Geng-Gang Wu, Yi-Cheng Xie, Guang-Xian Zhang, Wei Chen, Hai-Feng Yang, Qi-Long Liu, Wen-Hong Li, Wen-guang He, Yan-Nian Huang, Xian-Cheng Zeng BMC Cancer 2013, 13:412 (5 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

20.

763
Accesses

Research article   Open Access

Genome wide in silico SNP-tumor association analysis

Ping Qiu, Luquan Wang, Mitch Kostich, Wei Ding, Jason S Simon, Jonathan R Greene BMC Cancer 2004, 4:4 (29 January 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

755
Accesses

Research article   Open Access Highly Accessed

Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

Ho-Keun Kwon, Ji-Sun Hwang, Jae-Seon So, Choong-Gu Lee, Anupama Sahoo, Jae-Ha Ryu, Won Jeon, Byoung Ko, Chang-Rok Im, Sung Lee, Zee Park, Sin-Hyeog Im BMC Cancer 2010, 10:392 (24 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

746
Accesses

Research article   Open Access Highly Accessed

Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth

Vita M Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov, Carl Morrison, William G Cance BMC Cancer 2013, 13:342 (11 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

745
Accesses

Software   Open Access Highly Accessed

An electronic application for rapidly calculating Charlson comorbidity score

William H Hall, Ramanathan Ramachandran, Samir Narayan, Ashesh B Jani, Srinivasan Vijayakumar BMC Cancer 2004, 4:94 (20 December 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

720
Accesses

Research article   Open Access

Cancer risk assessment of ethyl carbamate in alcoholic beverages from Brazil with special consideration to the spirits cachaça and tiquira

Dirk W Lachenmeier, Maria CP Lima, Ian CC Nóbrega, José AP Pereira, Florence Kerr-Corrêa, Fotis Kanteres, Jürgen Rehm BMC Cancer 2010, 10:266 (8 June 2010)

Abstract | Full text | PDF | PubMed

25.

718
Accesses

Research article   Open Access Highly Accessed

Long-term exposure to hypoxia inhibits tumor progression of lung cancer in rats and mice

Lunyin Yu, Charles A Hales BMC Cancer 2011, 11:331 (3 August 2011)

Abstract | Full text | PDF | PubMed

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