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1.

838
Accesses

Study protocol   Open Access

Short-course radiotherapy followed by neo-adjuvant chemotherapy in locally advanced rectal cancer – the RAPIDO trial

Per J Nilsson, Boudewijn van Etten, Geke AP Hospers, Lars Påhlman, Cornelis JH van de Velde, Regina GH Beets-Tan, Lennart Blomqvist, Jannet C Beukema, Ellen Kapiteijn, Corrie AM Marijnen, Iris D Nagtegaal, Theo Wiggers, Bengt Glimelius BMC Cancer 2013, 13:279 (7 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

778
Accesses

Technical advance   Open Access Highly Accessed

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Hee-Sheung Lee, Nicholas CO Lee, Brenda R Grimes, Alexander Samoshkin, Artem V Kononenko, Ruchi Bansal, Hiroshi Masumoto, William C Earnshaw, Natalay Kouprina, Vladimir Larionov BMC Cancer 2013, 13:252 (22 May 2013)

Abstract | Full text | PDF | PubMed

3.

768
Accesses

Research article   Open Access Highly Accessed

Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model

Tao Hu, Chunhua Zhang, Qiongling Tang, Yanan Su, Bo Li, Long Chen, Zheng Zhang, Tianchi Cai, Yuechun Zhu BMC Cancer 2013, 13:251 (22 May 2013)

Abstract | Provisional PDF | PubMed

4.

764
Accesses

Research article   Open Access Highly Accessed

NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients

Kerstin Willander, Ravi Dutta, Jonas Ungerbäck, Rebeqa Gunnarsson, Gunnar Juliusson, Mats Fredrikson, Mats Linderholm, Peter Söderkvist BMC Cancer 2013, 13:274 (4 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

757
Accesses

Research article   Open Access Highly Accessed

Characteristic mTOR activity in Hodgkin-lymphomas offers a potential therapeutic target in high risk disease – a combined tissue microarray, in vitro and in vivo study

Ágnes Márk, Melinda Hajdu, Zsófia Váradi, Tamás Béla Sticz, Noémi Nagy, Judit Csomor, Lajos Berczi, Viktória Varga, Monika Csóka, László Kopper, Anna Sebestyén BMC Cancer 2013, 13:250 (22 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

740
Accesses

Research article   Open Access Highly Accessed

Destructive impact of t-lymphocytes, NK and mast cells on basal cell layers: implications for tumor invasion

Hongyan Yuan, Yi-Hsuan Hsiao, Yiyu Zhang, Jinlian Wang, Chao Yin, Rong Shen, Yiping Su BMC Cancer 2013, 13:258 (25 May 2013)

Abstract | Provisional PDF | PubMed

7.

722
Accesses

Reviewer acknowledgement   Open Access

Reviewer Acknowledgements

Christna Chap BMC Cancer 2013, 13:186 (5 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

714
Accesses

Case report   Open Access Highly Accessed

Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4–ALK-rearranged non–small–cell lung cancer harbored coexisting EGFR mutation

Akihiko Miyanaga, Kumi Shimizu, Rintaro Noro, Masahiro Seike, Kazuhiro Kitamura, Seiji Kosaihira, Yuji Minegishi, Takehito Shukuya, Akinobu Yoshimura, Masashi Kawamoto, Shinichi Tsuchiya, Koichi Hagiwara, Manabu Soda, Kengo Takeuchi, Nobuyuki Yamamoto, Hiroyuki Mano, Yuichi Ishikawa, Akihiko Gemma BMC Cancer 2013, 13:262 (29 May 2013)

Abstract | Full text | PDF | PubMed

9.

691
Accesses

Research article   Open Access Highly Accessed

Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain)

Pilar Blay, Iñigo Santamaría, Ana S Pitiot, María Luque, Marta G Alvarado, Ana Lastra, Yolanda Fernández, Ángeles Paredes, José MP Freije, Milagros Balbín BMC Cancer 2013, 13:243 (17 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

699
Accesses

Research article   Open Access Highly Accessed

Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

Peter A Fasching, Katharina Heusinger, Lothar Haeberle, Melitta Niklos, Alexander Hein, Christian M Bayer, Claudia Rauh, Ruediger Schulz-Wendtland, Mayada R Bani, Michael Schrauder, Laura Kahmann, Michael P Lux, Johanna D Strehl, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, David L Wachter BMC Cancer 2011, 11:486 (14 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

680
Accesses

Research article   Open Access Highly Accessed

Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression

Eira S Roth, David T Fetzer, Bruce J Barron, Usha A Joseph, Isis W Gayed, David Q Wan BMC Cancer 2009, 9:274 (7 August 2009)

Abstract | Full text | PDF | PubMed

12.

657
Accesses

Research article   Open Access Highly Accessed

Celecoxib alleviates tamoxifen-instigated angiogenic effects by ROS-dependent VEGF/VEGFR2 autocrine signaling

B N Kumar, Shashi Rajput, Kaushik Dey, Aditya Parekh, Subhasis Das, Abhijit Mazumdar, Mahitosh Mandal BMC Cancer 2013, 13:273 (3 June 2013)

Abstract | Full text | PDF | PubMed

13.

653
Accesses

Research article   Open Access Highly Accessed

The intraportal injection model: A practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer

Andreas Thalheimer, Christoph Otto, Marco Bueter, Bertram Illert, Stefan Gattenlohner, Martin Gasser, Detlef Meyer, Martin Fein, Christoph T Germer, Ana M Waaga-Gasser BMC Cancer 2009, 9:29 (24 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

649
Accesses

Research article   Open Access Highly Accessed

Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line

Sara R Martins-Neves, Áurio O Lopes, Anália do Carmo, Artur A Paiva, Paulo C Simões, Antero J Abrunhosa, Célia MF Gomes BMC Cancer 2012, 12:139 (4 April 2012)

Abstract | Full text | PDF | PubMed

15.

642
Accesses

Software   Open Access Highly Accessed

An electronic application for rapidly calculating Charlson comorbidity score

William H Hall, Ramanathan Ramachandran, Samir Narayan, Ashesh B Jani, Srinivasan Vijayakumar BMC Cancer 2004, 4:94 (20 December 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

642
Accesses

Research article   Open Access Highly Accessed

Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

Arantza Fariña Sarasqueta, Giusi Forte, Wim E Corver, Noel F de Miranda, Dina Ruano, Ronald van Eijk, Jan Oosting, Rob AEM Tollenaar, Tom van Wezel, Hans Morreau BMC Cancer 2013, 13:277 (5 June 2013)

Abstract | Full text | PDF | PubMed

17.

620
Accesses

Research article   Open Access Highly Accessed

Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer

Yutaka Yamamoto, Takashi Ishikawa, Yasuo Hozumi, Masahiko Ikeda, Hiroji Iwata, Hiroko Yamashita, Tatsuya Toyama, Takashi Chishima, Shigehira Saji, Mutsuko Yamamoto-Ibusuki, Hirotaka Iwase BMC Cancer 2013, 13:239 (16 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

18.

614
Accesses

Research article   Open Access Highly Accessed

Constructions of sex and intimacy after cancer: Q methodology study of people with cancer, their partners, and health professionals

Janette Perz, Jane M Ussher, Emilee Gilbert BMC Cancer 2013, 13:270 (31 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

601
Accesses

Research article   Open Access

Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma

Shao-Bo Liang, Yan-Ming Deng, Ning Zhang, Rui-Liang Lu, Hai Zhao, Hai-Yang Chen, Shao-En Li, Dong-Sheng Liu, Yong Chen BMC Cancer 2013, 13:260 (27 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

20.

586
Accesses

Research article   Open Access

Nuclear TK1 expression is an independent prognostic factor for survival in pre-malignant and malignant lesions of the cervix

Gang Chen, Cheng He, Ling Li, An Lin, Xiongwei Zheng, Ellen He, Sven Skog BMC Cancer 2013, 13:249 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

21.

569
Accesses

Research article   Open Access Highly Accessed

Gastric cancer surgery: Billroth I or Billroth II for distal gastrectomy?

Birendra K Sah, Ming-Min Chen, Min Yan, Zheng-Gang Zhu BMC Cancer 2009, 9:428 (9 December 2009)

Abstract | Full text | PDF | PubMed

22.

568
Accesses

Research article   Open Access Highly Accessed

Atypical glandular cells in conventional cervical smears: Incidence and follow-up

René Scheiden, Catherine Wagener, Ulrich Knolle, Walter Dippel, Catherine Capesius BMC Cancer 2004, 4:37 (19 July 2004)

Abstract | Full text | PDF | PubMed

23.

553
Accesses

Research article   Open Access Highly Accessed

Equol enhances tamoxifen’s anti-tumor activity by induction of caspase-mediated apoptosis in MCF-7 breast cancer cells

Christiana Charalambous, Chara A Pitta, Andreas I Constantinou BMC Cancer 2013, 13:238 (15 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

24.

546
Accesses

Research article   Open Access

Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer

Bhupendra Singh, Anwesha Chatterjee, Amruta M Ronghe, Nimee K Bhat, Hari K Bhat BMC Cancer 2013, 13:253 (22 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

25.

546
Accesses

Research article   Open Access

Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China

Sheng Zhou, Juan Cui, Zong Fan, Xue Li, Ji Li, Bao Liu, Dong Zhang, Hong Liu, Xue Zhao, Xin Song, Ran Wang, Ze Yan, Hui Yi, Li Wang BMC Cancer 2013, 13:259 (25 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

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