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  • Image attributed to:

    Protein filaments as fences

    Simulation models of the the pooling of phospholipid PIP2 show that protein filaments must consist of multiple rows or be buried below the surface of the membrane to act as effective molecular fences.

    BMC Biophysics 2014, 7:13
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    Tools to model molecular reactions

    To simulate biophysical interactions in the cell, various particle-based reaction-diffusion software packages are available, all with differing degrees of sophistication, computational cost and utility in answering biological questions.

    BMC Biophysics 2014, 7:11
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    Analyzing asymmetric cell division

    An efficient analytical model can quantifiably assess the contributions of the various active and passive processes that drive unequal segregation of different macromolecules, organelles and complexes during cell division in yeast.

    BMC Biophysics 2014, 7:10
  • Image attributed to: Fig 4C Tamamis et al BMC Biophysics

    Modelling GPCR protein-ligand complexes

    A computational framework for modelling the complex between the G-protein‐coupled  receptor C5aR and its PMX53 antagonist peptide agree well with experimental data and may form the basis for generating reliable models of protein-ligand complexes of unknown structure.

    BMC Biophysics 2014, 7:5
  • Image attributed to: Bro Jeffrey Pioquinto, SJ_Flickr cc

    Next-generation training in biophysics

    An innovative graduate training program in biophysics and structural biology aims to integrate students in activities usually undertaken by more senior faculty members, empowering them to become better prepared for a career in academia.

    BMC Biophysics 2014, 7:6
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