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1.
Drop drying on surfaces determines chemical reactivity - the specific case of immobilization of oligonucleotides on microarrays
Jens Sobek, Catharine Aquino, Wilfried Weigel, Ralph Schlapbach BMC Biophysics 2013, 6 :8 (12 June 2013)
Abstract | Full text | PDF
| ePUB | PubMed
2.
A biophysical model for transcription factories
Ana Z Canals-Hamann, Ricardo das Neves, Joyce E Reittie, Carlos Iñiguez, Shamit Soneji, Tariq Enver, Veronica J Buckle, Francisco J Iborra BMC Biophysics 2013, 6 :2 (9 February 2013)
Abstract | Full text | PDF
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Editor’s summary
Chromatin can act as a multi-block copolymer with active-inactive monomers that spontaneously self-organize to form microdomains, demonstrating that geometrical constraints alone can potentially yield an organized transcription factory.
3.
Pulling chromatin apart: Unstacking or Unwrapping?
Jean Marc Victor, Jordanka Zlatanova, Maria Barbi, Julien Mozziconacci BMC Biophysics 2012, 5 :21 (27 November 2012)
Abstract | Full text | PDF
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Editor’s summary
A zig-zag model of chromatin fiber morphology is able to quantitatively explain the mechanical properties of chromatin under external stress, and provides an alternative explanation to the widespread solenoid model interpretation.
4.
Hierarchies in eukaryotic genome organization: Insights from polymer theory and simulations
Balaji VS Iyer, Martin Kenward, Gaurav Arya BMC Biophysics 2011, 4 :8 (15 April 2011)
Abstract | Full text | PDF
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Editor’s summary
Gaurav Arya and colleagues review results from state-of-the-art microscopy and chromosome conformation capture techniques that are being used to understand the three dimensional structure of the genome and the physical principles governing its folding.
