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Research article   Open Access

Self-consistent field theory for the interactions between keratin intermediate filaments

Anna Akinshina, Etienne Jambon-Puillet, Patrick B Warren, Massimo G Noro BMC Biophysics 2013, 6:12 (5 September 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Kinetic effects of TiO2 fine particles and nanoparticles aggregates on the nanomechanical properties of human neutrophils assessed by force spectroscopy

Everton Luis da Rosa BMC Biophysics 2013, 6:11 (19 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies

Anke Steinbach, Christine K Maurer, Elisabeth Weidel, Claudia Henn, Christian Brengel, Rolf W Hartmann, Matthias Negri BMC Biophysics 2013, 6:10 (1 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

Interactions of the amphiphiles arbutin and tryptophan with phosphatidylcholine and phosphatidylethanolamine bilayers in the dry state

Antoaneta V Popova, Dirk K Hincha BMC Biophysics 2013, 6:9 (24 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

Drop drying on surfaces determines chemical reactivity - the specific case of immobilization of oligonucleotides on microarrays

Jens Sobek, Catharine Aquino, Wilfried Weigel, Ralph Schlapbach BMC Biophysics 2013, 6:8 (12 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

Commentary   Open Access Highly Accessed

Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?

Xiaodong Pang, Huan-Xiang Zhou BMC Biophysics 2013, 6:7 (3 June 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Xiaodong Pang and Huan-Xiang Zhou discuss a recent study in BMC Biophysics that sheds new light on mechanisms of receptor activation, and argue that coexistence of monomers and dimers may be common for cell surface receptors.

Research article   Open Access

Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells

Marina S Dietz, Daniel Haße, Davide M Ferraris, Antonia Göhler, Hartmut H Niemann, Mike Heilemann BMC Biophysics 2013, 6:6 (3 June 2013)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central |  Editor’s summary

Single-molecule photobleaching reveals that the MET receptor exists as both dimers and monomers on cell membranes in the absence of a ligand, with the proportion of dimers increasing significantly upon ligand binding.

Methodology article   Open Access

Time-resolved force distribution analysis

Bogdan I Costescu, Frauke Gräter BMC Biophysics 2013, 6:5 (1 May 2013)

Abstract | Full text | PDF | ePUB |  Editor’s summary

Time-resolved force distribution analysis is a new method to monitor the fluctuations of internal forces in complex macromolecular structures, and is an alternative approach to coordinate-based methods for analyzing structural transitions.

Methodology article   Open Access

Improving accuracy of cell and chromophore concentration measurements using optical density

John A Myers, Brandon S Curtis, Wayne R Curtis BMC Biophysics 2013, 6:4 (22 April 2013)

Abstract | Full text | PDF

Research article   Open Access

Wavelet-based protocols for ion channel electrophysiology

Armin Kargol BMC Biophysics 2013, 6:3 (14 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

A biophysical model for transcription factories

Ana Z Canals-Hamann, Ricardo das Neves, Joyce E Reittie, Carlos Iñiguez, Shamit Soneji, Tariq Enver, Veronica J Buckle, Francisco J Iborra BMC Biophysics 2013, 6:2 (9 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Chromatin can act as a multi-block copolymer with active-inactive monomers that spontaneously self-organize to form microdomains, demonstrating that geometrical constraints alone can potentially yield an organized transcription factory.

Research article   Open Access

Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences

Rasha Bassam, Ilya Digel, Juergen Hescheler, Ayseguel Temiz Artmann, Gerhard M Artmann BMC Biophysics 2013, 6:1 (4 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Stochastic dynamics of virus capsid formation: direct versus hierarchical self-assembly

Johanna E Baschek, Heinrich C R Klein, Ulrich S Schwarz BMC Biophysics 2012, 5:22 (17 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Computational modeling of the way that viruses are able to self-assemble their protein capsid coats suggests that for complex viruses with more stable bonds, a piecemeal hierarchical assembly process is most likely.

Research article   Open Access Highly Accessed

Pulling chromatin apart: Unstacking or Unwrapping?

Jean Marc Victor, Jordanka Zlatanova, Maria Barbi, Julien Mozziconacci BMC Biophysics 2012, 5:21 (27 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A zig-zag model of chromatin fiber morphology is able to quantitatively explain the mechanical properties of chromatin under external stress, and provides an alternative explanation to the widespread solenoid model interpretation.

Research article   Open Access

Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells

Frederik W Lund, Michael A Lomholt, Lukasz M Solanko, Robert Bittman, Daniel Wüstner BMC Biophysics 2012, 5:20 (18 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Hierarchical super-structure identified by polarized light microscopy, electron microscopy and nanoindentation: Implications for the limits of biological control over the growth mode of abalone sea shells

Andreas S Schneider, Birgit Heiland, Nicolas J Peter, Christina Guth, Eduard Arzt, Ingrid M Weiss BMC Biophysics 2012, 5:19 (12 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The hierarchical super-structure of abalone mollusc shells can be revealed by conventional light microscopy methods, opening the potential to study shell growth mechanisms in vivo at high resolution.

Commentary   Open Access Highly Accessed

Intracellular chemical gradients: morphing principle in bacteria

Robert G Endres BMC Biophysics 2012, 5:18 (7 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Robert Endres discusses a new study in BMC Biophysics that supports the emerging view that intracellular chemical gradients can exist in bacterial cells, and how these may limit in vitro analyses.

Research article   Open Access Highly Accessed

Physical constraints on the establishment of intracellular spatial gradients in bacteria

Carolina Tropini, Naveed Rabbani, Kerwyn Huang BMC Biophysics 2012, 5:17 (29 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Effects of spermine NONOate and ATP on the thermal stability of hemoglobin

Rasha Bassam, Juergen Hescheler, Ayseguel Temiz-Artmann, Gerhard M Artmann, Ilya Digel BMC Biophysics 2012, 5:16 (28 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Flexibility of EF-hand motifs: structural and thermodynamic studies of Calcium Binding Protein-1 from Entamoeba histolytica with Pb2+, Ba2+, and Sr2+

Shivesh Kumar, Ejaz Ahmad, Sanjeev Kumar, Rizwan Khan, Samudrala Gourinath BMC Biophysics 2012, 5:15 (20 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Molecular dynamics simulations on aqueous two-phase systems - Single PEG-molecules in solution

Stefan A Oelmeier, Florian Dismer, Jürgen Hubbuch BMC Biophysics 2012, 5:14 (8 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors

Subhodeep Moitra, Kalyan C Tirupula, Judith Klein-Seetharaman, Christopher Langmead BMC Biophysics 2012, 5:13 (29 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Intrinsic thermodynamics of ethoxzolamide inhibitor binding to human carbonic anhydrase XIII

Lina Baranauskienė, Daumantas Matulis BMC Biophysics 2012, 5:12 (7 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase

Maria L Kireeva, Kristopher Opron, Steve A Seibold, Céline Domecq, Robert I Cukier, Benoit Coulombe, Mikhail Kashlev, Zachary F Burton BMC Biophysics 2012, 5:11 (7 June 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The catalytic confirmation of the RNA polymerase ternary elongation complex (TEC) has a closed trigger loop with a relatively dehydrated active site, in contrast to the inactive open confirmation of the trigger loop which supports translocation.

Correspondence   Open Access Highly Accessed

Can dietary fibre help provide safer food products for sufferers of gluten intolerance? A well-established biophysical probe may help towards providing an answer

M Kök, Richard Gillis, Shirley Ang, David Lafond, Arthur S Tatham, Gary Adams, Stephen E Harding BMC Biophysics 2012, 5:10 (17 May 2012)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Stephen Harding and colleagues speculate on the role that the ultracentrifuge assay procedure could play in detecting non-toxic biopolymers capable of sequestering ingested gluten peptides, with the eventual aim of reducing gluten intolerance symptoms.

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