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Self-consistent field theory for the interactions between keratin intermediate filaments
Anna Akinshina, Etienne Jambon-Puillet, Patrick B Warren, Massimo G Noro BMC Biophysics 2013, 6:12 (5 September 2013)
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Kinetic effects of TiO2 fine particles and nanoparticles aggregates on the nanomechanical properties of human neutrophils assessed by force spectroscopy
Everton Luis da Rosa BMC Biophysics 2013, 6:11 (19 August 2013)
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Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies
Anke Steinbach, Christine K Maurer, Elisabeth Weidel, Claudia Henn, Christian Brengel, Rolf W Hartmann, Matthias Negri BMC Biophysics 2013, 6:10 (1 August 2013)
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Interactions of the amphiphiles arbutin and tryptophan with phosphatidylcholine and phosphatidylethanolamine bilayers in the dry state
Antoaneta V Popova, Dirk K Hincha BMC Biophysics 2013, 6:9 (24 July 2013)
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Drop drying on surfaces determines chemical reactivity - the specific case of immobilization of oligonucleotides on microarrays
Jens Sobek, Catharine Aquino, Wilfried Weigel, Ralph Schlapbach BMC Biophysics 2013, 6:8 (12 June 2013)
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Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?
Xiaodong Pang, Huan-Xiang Zhou BMC Biophysics 2013, 6:7 (3 June 2013)
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Editor’s summary
Xiaodong Pang and Huan-Xiang Zhou discuss a recent study in BMC Biophysics that sheds new light on mechanisms of receptor activation, and argue that coexistence of monomers and dimers may be common for cell surface receptors.
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Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells
Marina S Dietz, Daniel Haße, Davide M Ferraris, Antonia Göhler, Hartmut H Niemann, Mike Heilemann BMC Biophysics 2013, 6:6 (3 June 2013)
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Single-molecule photobleaching reveals that the MET receptor exists as both dimers and monomers on cell membranes in the absence of a ligand, with the proportion of dimers increasing significantly upon ligand binding.
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Time-resolved force distribution analysis
Bogdan I Costescu, Frauke Gräter BMC Biophysics 2013, 6:5 (1 May 2013)
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Time-resolved force distribution analysis is a new method to monitor the fluctuations of internal forces in complex macromolecular structures, and is an alternative approach to coordinate-based methods for analyzing structural transitions.
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Improving accuracy of cell and chromophore concentration measurements using optical density
John A Myers, Brandon S Curtis, Wayne R Curtis BMC Biophysics 2013, 6:4 (22 April 2013)
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Wavelet-based protocols for ion channel electrophysiology
Armin Kargol BMC Biophysics 2013, 6:3 (14 March 2013)
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A biophysical model for transcription factories
Ana Z Canals-Hamann, Ricardo das Neves, Joyce E Reittie, Carlos Iñiguez, Shamit Soneji, Tariq Enver, Veronica J Buckle, Francisco J Iborra BMC Biophysics 2013, 6:2 (9 February 2013)
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Chromatin can act as a multi-block copolymer with active-inactive monomers that spontaneously self-organize to form microdomains, demonstrating that geometrical constraints alone can potentially yield an organized transcription factory.
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Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences
Rasha Bassam, Ilya Digel, Juergen Hescheler, Ayseguel Temiz Artmann, Gerhard M Artmann BMC Biophysics 2013, 6:1 (4 January 2013)
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Stochastic dynamics of virus capsid formation: direct versus hierarchical self-assembly
Johanna E Baschek, Heinrich C R Klein, Ulrich S Schwarz BMC Biophysics 2012, 5:22 (17 December 2012)
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Computational modeling of the way that viruses are able to self-assemble their protein capsid coats suggests that for complex viruses with more stable bonds, a piecemeal hierarchical assembly process is most likely.
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Pulling chromatin apart: Unstacking or Unwrapping?
Jean Marc Victor, Jordanka Zlatanova, Maria Barbi, Julien Mozziconacci BMC Biophysics 2012, 5:21 (27 November 2012)
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A zig-zag model of chromatin fiber morphology is able to quantitatively explain the mechanical properties of chromatin under external stress, and provides an alternative explanation to the widespread solenoid model interpretation.
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Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells
Frederik W Lund, Michael A Lomholt, Lukasz M Solanko, Robert Bittman, Daniel Wüstner BMC Biophysics 2012, 5:20 (18 October 2012)
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Hierarchical super-structure identified by polarized light microscopy, electron microscopy and nanoindentation: Implications for the limits of biological control over the growth mode of abalone sea shells
Andreas S Schneider, Birgit Heiland, Nicolas J Peter, Christina Guth, Eduard Arzt, Ingrid M Weiss BMC Biophysics 2012, 5:19 (12 September 2012)
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The hierarchical super-structure of abalone mollusc shells can be revealed by conventional light microscopy methods, opening the potential to study shell growth mechanisms in vivo at high resolution.
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Intracellular chemical gradients: morphing principle in bacteria
Robert G Endres BMC Biophysics 2012, 5:18 (7 September 2012)
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Robert Endres discusses a new study in BMC Biophysics that supports the emerging view that intracellular chemical gradients can exist in bacterial cells, and how these may limit in vitro analyses.
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Physical constraints on the establishment of intracellular spatial gradients in bacteria
Carolina Tropini, Naveed Rabbani, Kerwyn Huang BMC Biophysics 2012, 5:17 (29 August 2012)
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Effects of spermine NONOate and ATP on the thermal stability of hemoglobin
Rasha Bassam, Juergen Hescheler, Ayseguel Temiz-Artmann, Gerhard M Artmann, Ilya Digel BMC Biophysics 2012, 5:16 (28 August 2012)
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Flexibility of EF-hand motifs: structural and thermodynamic studies of Calcium Binding Protein-1 from Entamoeba histolytica with Pb2+, Ba2+, and Sr2+
Shivesh Kumar, Ejaz Ahmad, Sanjeev Kumar, Rizwan Khan, Samudrala Gourinath BMC Biophysics 2012, 5:15 (20 August 2012)
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Molecular dynamics simulations on aqueous two-phase systems - Single PEG-molecules in solution
Stefan A Oelmeier, Florian Dismer, Jürgen Hubbuch BMC Biophysics 2012, 5:14 (8 August 2012)
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A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors
Subhodeep Moitra, Kalyan C Tirupula, Judith Klein-Seetharaman, Christopher Langmead BMC Biophysics 2012, 5:13 (29 June 2012)
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Intrinsic thermodynamics of ethoxzolamide inhibitor binding to human carbonic anhydrase XIII
Lina Baranauskienė, Daumantas Matulis BMC Biophysics 2012, 5:12 (7 June 2012)
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Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase
Maria L Kireeva, Kristopher Opron, Steve A Seibold, Céline Domecq, Robert I Cukier, Benoit Coulombe, Mikhail Kashlev, Zachary F Burton BMC Biophysics 2012, 5:11 (7 June 2012)
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Editor’s summary
The catalytic confirmation of the RNA polymerase ternary elongation complex (TEC) has a closed trigger loop with a relatively dehydrated active site, in contrast to the inactive open confirmation of the trigger loop which supports translocation.
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Can dietary fibre help provide safer food products for sufferers of gluten intolerance? A well-established biophysical probe may help towards providing an answer
M Kök, Richard Gillis, Shirley Ang, David Lafond, Arthur S Tatham, Gary Adams, Stephen E Harding BMC Biophysics 2012, 5:10 (17 May 2012)
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Stephen Harding and colleagues speculate on the role that the ultracentrifuge assay procedure could play in detecting non-toxic biopolymers capable of sequestering ingested gluten peptides, with the eventual aim of reducing gluten intolerance symptoms.
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