Most Recent Articles: BMC Biologyhttps://bmcbiol.biomedcentral.comMost Recent Articles: BMC BiologyModeling antibody drug conjugate potential using a granzyme B antibody fusion proteinhttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01860-xAntibody drug conjugates (ADCs) constitute a promising class of targeted anti-tumor therapeutics that harness the selectivity of monoclonal antibodies with the potency of cytotoxic drugs. ADC development is be...Research articleThu, 14 Mar 2024 00:00:00 GMThttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01860-xTrevor S. Anderson, Amanda L. McCormick, Savanna L. Smith and Devin B. Lowe2024-03-14T00:00:00ZDNA methylation haplotype block signatures responding to Staphylococcus aureus subclinical mastitis and association with production and health traitshttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01843-yDNA methylation has been documented to play vital roles in diseases and biological processes. In bovine, little is known about the regulatory roles of DNA methylation alterations on production and health trait...Research articleThu, 14 Mar 2024 00:00:00 GMThttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01843-yMengqi Wang, Nathalie Bissonnette, Mario Laterrière, Pier-Luc Dudemaine, David Gagné, Jean-Philippe Roy, Marc-André Sirard and Eveline M. Ibeagha-Awemu2024-03-14T00:00:00ZThe fitness trade-off between growth and stress resistance determines the phenotypic landscapehttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01856-7A central challenge in biology is to discover a principle that determines individual phenotypic differences within a species. The growth rate is particularly important for a unicellular organism, and the growt...Research articleWed, 13 Mar 2024 00:00:00 GMThttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01856-7Dongsan Kim, Chae Young Hwang and Kwang-Hyun Cho2024-03-13T00:00:00ZAn odorant receptor mediates the avoidance of Plutella xylostella against parasitoidhttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01862-9Ecosystems are brimming with myriad compounds, including some at very low concentrations that are indispensable for insect survival and reproduction. Screening strategies for identifying active compounds are t...Research articleWed, 13 Mar 2024 00:00:00 GMThttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01862-9Yipeng Liu, Sai Zhang, Song Cao, Emmanuelle Jacquin-Joly, Qiong Zhou, Yang Liu and Guirong Wang2024-03-13T00:00:00ZMitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophilahttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01858-5Mitochondria participate in various cellular processes including energy metabolism, apoptosis, autophagy, production of reactive oxygen species, stress responses, inflammation and immunity. However, the role o...Research articleWed, 13 Mar 2024 00:00:00 GMThttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01858-5Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale and Tiina S. Salminen2024-03-13T00:00:00Z