2010 November

Spontaneous focal activation of invariant natural killer T cells in the kidney

Focal expression (green-blue) of an interferon-gamma-inducible protein (Irga6) in tubular epithelial cells of the tubular cortex of normal mouse kidney is due to local activation and secretion of interferon gamma by invariant natural killer-like T (iNKT) cells, probably activated by a sporadically expressed endogenous ligand. Similar foci are found in the liver.

Taken from: Jonathan Howard et al., 2010, BMC Biology [View article]

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