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Volume 4 (2006) - March 2006

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Research article   Open Access Highly Accessed

Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25

Tod R Clapp, Kathryn F Medler, Sami Damak, Robert F Margolskee, Sue C Kinnamon BMC Biology 2006, 4:7 (30 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Taste receptor cells in mice for bitter, sweet and umami use G-protein coupled receptors but lack calcium currents and presynaptic SNAP-25 protein, indicating that they do not use conventional synapses to relay taste stimuli.

Research article   Open Access Highly Accessed

Streambed microstructure predicts evolution of development and life history mode in the plethodontid salamander Eurycea tynerensis

Ronald M Bonett, Paul T Chippindale BMC Biology 2006, 4:6 (2 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Whether a salamander remains in aquatic form or metamorphoses depends on the nature of the local streambed sediment, demonstrating how habitat changes drive evolution, potentially resulting in speciation.