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Volume 3 (2005) - September 2005

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Research article   Open Access Highly Accessed

The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications

The Rice Chromosomes 11 and 12 Sequencing Consortia* BMC Biology 2005, 3:20 (27 September 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Analysis of the complete sequences of rice chromosomes 11 and 12, comprising 1/7 of the whole genome, identifies nearly 6000 genes, of which more than 5% are involved in disease resistance or defense, a greater proportion than on other chromosomes.

Research article   Open Access Highly Accessed

Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans

James A Timmons, Eva Jansson, Helene Fischer, Thomas Gustafsson, Paul L Greenhaff, John Ridden, Jonathan Rachman, Carl Sundberg BMC Biology 2005, 3:19 (2 September 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

High-intensity aerobic training upregulates expression of several extracellular matrix genes in human muscle, including the genes for angiopoietin 1 and TIE2, but only when aerobic capacity increases.