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Volume 3 (2005) - August 2005

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Research article   Open Access Highly Accessed

Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo

Carrie Dickey-Sims, Anthony J Robertson, Dawn E Rupp, John J McCarthy, James A Coffman BMC Biology 2005, 3:18 (2 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Sea urchin embryonic knockdown of either Runx protein or protein kinase C causes extensive apoptosis, while Runx deficiency is rescued by inhibition of caspase-3 and by PKC mRNA injection, providing evidence that Runx maintains PKC levels to ensure cell survival.

Research article   Open Access

Echolocation calls and communication calls are controlled differentially in the brainstem of the bat Phyllostomus discolor

Thomas Fenzl, Gerd Schuller BMC Biology 2005, 3:17 (1 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Contralateral blockade of the paralemniscal area of bats' brains suppresses echolocation calls elicted in the periaqueductal gray matter, but not communication calls, suggesting that the paralemniscal area is essential for echolocation call control.