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Volume 11 (2013) - February 2013

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Research article   Open Access

A functional genomics screen for microRNA regulators of NF-kappaB signaling

Anthony O Olarerin-George, Lauren Anton, Yih-Chii Hwang, Michal A Elovitz, John B Hogenesch BMC Biology 2013, 11:19 (28 February 2013)

Abstract | Provisional PDF

Editorial   Open Access

Q&A: Re-review opt-out and painless publishing

Miranda Robertson BMC Biology 2013, 11:18 (28 February 2013)

Abstract | Full text | PDF |  Editor’s summary

BMC Biology operates on the principle that the function of a journal is to facilitate publication of sound research results. Miranda Robertson reviews in Q&A format the journal’s re-review opt-out policy and how it has worked over the four years of its operation.

Comment   Open Access

Open questions: What is there left for cell biologists to do?

Sean Munro BMC Biology 2013, 11:16 (27 February 2013)

Abstract | Full text | PDF |  Editor’s summary

In a contribution to the 10th anniversary series on open questions in biology, Sean Munro asks provocatively what there is left for cell biologists to do, and with great elan and a touch of waspish humor produces five unanswered questions on issues from the special properties of non-dividing cells to the architecture of the brain.

Research article   Open Access

Genome mining for methanobactins

Grace E Kenney, Amy C Rosenzweig BMC Biology 2013, 11:17 (26 February 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Methanotrophic bacteria have potential as a biological methane sink, and methanobactins are a set of peptides important in regulating this activity. A genome mining study highlights genes involved in methanobactin production, but also suggests that not all methanotrophs have them.

Research article   Open Access

Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

Jose Vinuelas, Gael Kaneko, Antoine Coulon, Elodie Vallin, Valerie Morin, Camila Mejia-Pous, Jean-Jacques Kupiec, Guillaume Beslon, Olivier Gandrillon BMC Biology 2013, 11:15 (25 February 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A combined biological and computational approach adds further detail to a growing body of evidence that most genes undergo short bursts of transcription interspersed between long periods of downtime.

Commentary   Open Access

Predicting the evolution of antibiotic resistance

Martijn F Schenk, J Arjan GM de Visser BMC Biology 2013, 11:14 (22 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Commenting on research in BMC Evolutionary Biology, Arjan de Visser and Martijn Schenk discuss how two genetic properties, pleiotropy and epistasis, might help us to predict the evolution of antibiotic resistance.

Research article   Open Access

Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles

Jingxia Xu, Thomas Gridley BMC Biology 2013, 11:13 (13 February 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

MST1, a key player, in enhancing fast skeletal muscle atrophy

Bin Wei, Wen Dui, Dong Liu, Yan Xing, Zengqqiang Yuan, Guangju Ji BMC Biology 2013, 11:12 (1 February 2013)

Abstract | Provisional PDF | PubMed


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