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Functional divergence of the brain-size regulating
gene MCPH1 during primate evolution and the
origin of humans
Lei Shi, Ming Li, Qiang Lin, Xuebin Qi, Bing Su BMC Biology 2013, 11:62 (22 May 2013)
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Bacteroides thetaiotaomicron and Faecalibacterium
prausnitzii influence the production of mucus
glycans and the development of goblet cells in the
colonic epithelium of a gnotobiotic model rodent
Laura Wrzosek, Sylvie Miquel, Marie-Louise Noordine, Stephan Bouet, Marie Joncquel Chevalier-Curt, Véronique Robert, Catherine Philippe, Chantal Bridonneau, Claire Cherbuy, Catherine Robbe-Masselot, Philippe Langella, Muriel Thomas BMC Biology 2013, 11:61 (21 May 2013)
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In pursuit of an HIV vaccine: an interview with Andrew McMichael
Andrew J McMichael BMC Biology 2013, 11:60 (21 May 2013)
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Can the immune system be induced to protect itself against HIV infection? Andrew McMichael gives his perspective in an interview, explaining the challenges faced in making a vaccine and why he remains optimistic about the potential of eliciting strong T cell responses for controlling the virus.
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Thirty years on: HIV receptor gymnastics and the prevention of infection
Robin A Weiss BMC Biology 2013, 11:57 (21 May 2013)
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Robin Weiss, in an article to mark the 30th anniversary of the discovery of the human immunodeficiency virus (HIV), reviews the complex interactions of the virus with the specialized surface molecules by which it gains entry into cells, and how this has led to drugs that block it.
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Q&A: Antibiotic resistance: what more do we know and what more can we do?
Gerard D Wright BMC Biology 2013, 11:51 (17 May 2013)
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Antibiotic resistance is both an ancient phenomenon and a worsening medical problem. Gerard Wright explains why, and what should be done about it.
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On the origin of POU5F1
Stephen Frankenberg, Marilyn B Renfree BMC Biology 2013, 11:56 (9 May 2013)
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Spatial and temporal in vivo analysis of circulating and sessile immune cells in mosquitoes: hemocyte mitosis following infection
Jonas G King, Julián F Hillyer BMC Biology 2013, 11:55 (30 April 2013)
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Observations on the number, location, phagocytic activity and cell division of hemocytes in the body cavity of mosquitoes sheds new light on the biology of insect immune system cells.
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Somatic and visceral nervous systems - an ancient duality
Paola Bertucci, Detlev Arendt BMC Biology 2013, 11:54 (30 April 2013)
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The idea that vertebrates are composed of a ‘visceral’ and ‘somatic’ self, responding to internal and external stimuli, respectively, was first put forward in the 19th century. Now, molecular fingerprinting indicates a duality between the somatic and visceral nervous systems that appears to predate Bilataria.
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Ancient origin of somatic and visceral neurons
Marc Nomaksteinsky, Stefan Kassabov, Zoubida Chettouh, Henri-Corto Stoeklé, Laure Bonnaud, Gilles Fortin, Eric R Kandel, Jean-François Brunet BMC Biology 2013, 11:53 (30 April 2013)
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The great American palaeontologist and anatomist Alfred Romer speculated that early in animal life, an emerging somatic nervous system, focused on the outside world, struggled to dominate the visceral nervous system that takes care of the internal systems that keep us alive. Jean-François Brunet and colleagues identify the molecular signatures that tell the evolutionary tale of this duality.
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Statistical support for the hypothesis of developmental constraint in marsupial skull evolution
C Verity Bennett, Anjali Goswami BMC Biology 2013, 11:52 (26 April 2013)
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High-density linkage mapping in a pine tree reveals a genomic region associated with inbreeding depression and provides clues to the extent and distribution of meiotic recombination
Emilie Chancerel, Jean-Baptiste Lamy, Isabelle Lesur, Céline Noirot, Christophe Klopp, François Ehrenmann, Christophe Boury, Grégoire Le Provost, Philippe Label, Céline Lalanne, Valérie Léger, Franck Salin, Jean-Marc Gion, Christophe Plomion BMC Biology 2013, 11:50 (18 April 2013)
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Radial glial cells play a key role in echinoderm neural regeneration
Vladimir S Mashanov, Olga R Zueva, José E García-Arrarás BMC Biology 2013, 11:49 (18 April 2013)
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Repair of a cut radial nerve cord in a sea cucumber is mediated by radial glial cells that dedifferentiate, divide and give rise to new neurons.
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Tropical rain forest evolution: palms as a model group
Thomas LP Couvreur, William J Baker BMC Biology 2013, 11:48 (15 April 2013)
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White-nose syndrome in bats: illuminating the darkness
Paul M Cryan, Carol Meteyer, Justin G Boyles, David S Blehert BMC Biology 2013, 11:47 (15 April 2013)
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Seeing the Tree of Life behind the phylogenetic forest
Pere Puigbò, Yuri I Wolf, Eugene V Koonin BMC Biology 2013, 11:46 (15 April 2013)
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Arthropods and inherited bacteria: from counting the symbionts to understanding how symbionts count
Olivier Duron, Gregory DD Hurst BMC Biology 2013, 11:45 (15 April 2013)
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Segment assembly, structure alignment and iterative simulation in protein structure prediction
Yang Zhang, Jeffrey Skolnick BMC Biology 2013, 11:44 (15 April 2013)
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Systematic curation of protein and genetic interaction data for computable biology
Kara Dolinski, Andrew Chatr-aryamontri, Mike Tyers BMC Biology 2013, 11:43 (15 April 2013)
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Neurosensory transmission without a synapse: new perspectives on taste signaling
Sue C Kinnamon BMC Biology 2013, 11:42 (15 April 2013)
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Fuzzy species revisited
William P Hanage BMC Biology 2013, 11:41 (15 April 2013)
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The new micro-kingdoms of eukaryotes
Jan Pawlowski BMC Biology 2013, 11:40 (15 April 2013)
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Tenth anniversary updates from our authors
Penelope Austin, Kester Jarvis BMC Biology 2013, 11:39 (15 April 2013)
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Of flies and men: insights on organismal metabolism from fruit flies
Akhila Rajan, Norbert Perrimon BMC Biology 2013, 11:38 (15 April 2013)
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For many reasons metabolism is now a high-profile topic, and in an update to mark the tenth anniversary of BMC Biology, Norbert Perrimon and Akhila Rajan review the remarkable similarities that make Drosophila a model for mammalian metabolism, and some recent advances made possible by the advantages of this model organism.
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Drugging Hedgehog: signaling the pathway to translation
Tom J Carney, Philip W Ingham BMC Biology 2013, 11:37 (15 April 2013)
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Editor’s summary
Ten years ago Jeff Porter and colleagues published a screen for small-molecule modulators of the Hedgehog signaling pathway in the Journal of Biology. For BMC Biology’s 10th anniversary, Tom Carney and Philip Ingham discuss the far-reaching clinical impact of some of the agonists and antagonists they discovered.
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Domesticating the beast
Virginia Walbot BMC Biology 2013, 11:35 (15 April 2013)
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Editor’s summary
In 2009, Virginia Walbot commented ‘Are we training pit bulls to review our manuscripts?’ Revisiting the topic, she asks if we can tame our pit bull reviewers by involving students more in peer review and teaching them to see things from an authors’ perspective and the perspective of the journal that is responsible for making a decision on publication.
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