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BMC Biology

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Maria Kowalczuk PhD


Welcome to BMC Biology published by BioMed Central
BMC Biology - the flagship biology journal of the BMC series - publishes research and methodology articles of special importance and broad interest in any area of biology and biomedical sciences. BMC Biology (ISSN 1741-7007) is covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Zoological Record, Thomson Reuters (ISI) and Google Scholar.


BMC  Featured articles   

image from Jupiterimages www.jiunlimited.com
BMC Biology 2009, 7:79
Pigs reared indoors or in isolation have a less healthy gut microbiota than outdoor-reared pigs, and signs of immune activation in gut tissues, reinforcing human data associating childhood hygiene with inflammatory bowel disease.
B. pseudomallei colonies. credits: Gavin Koh
BMC Biology 2009, 7:78
Despite a high level of lateral gene transfer, the phylogeny of Burkholderia pseudomallei is resolved by SNPs in orthologous shared regions, enabling a wider gene-based analysis to define two populations, ancestral Australian, and South East Asian, separated by the Wallace Line.
Wikipedia - Public Domain
BMC Biology 2009, 7:77
A high throughput 3-D culture system succeeds in establishing glandular acini from a human mammary epithelial cell line, and demonstrates the importance of basal polarity-mediated signals and collagen IV in recapitulating apical polarity.
image from manuscript
BMC Biology 2009, 7:76
Bacterial signal recognition particle receptor (FtsY) is almost exclusively membrane-bound in vivo and this localization is important for its role in cotranslational targeting, overturning previous indications that it functioned as a cytosolic protein.
Wikipedia - Public Domain
BMC Biology 2009, 7:75
An approach to identifying the physiological targets of ubiquitin receptors and the biological circuits they regulate is validated by screening for genes whose overexpression slows the growth of yeast cells lacking the ubiquitin-binding proteins Rad23 and Dsk2


BMC  Latest articles published in BMC Biology        [more info]


Research article
Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
Imke E Mulder, Bettina Schmidt, Christopher R Stokes, Marie Lewis, Mick Bailey, Rustam I Aminov, James I Prosser, Bhupinder P Gill, John R Pluske, Claus-Dieter Mayer, Corran Musk, Denise Kelly
BMC Biology 2009, 7:79 (20November2009)
[Abstract] [Provisional PDF]

Research article
Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer
Talima Pearson, Philip Giffard, Stephen Beckstrom-Sternberg, Raymond Auerbach, Heidie Hornstra, Apichai Tuanyok, Erin P Price, Mindy B Glass, Benjamin Leadem, James S Beckstrom-Sternberg, Gerard J Allan, Jeffrey T Foster, David M Wagner, Richard T Okinaka, Siew Hoon Sim, Ofori Pearson, Zaining Wu, Jean Chang, Rajinder Kaul, Alex R Hoffmaster, Thomas S Brettin, Richard A Robison, Mark Mayo, Jay E Gee, Patrick Tan, Bart J Currie, Paul Keim
BMC Biology 2009, 7:78 (18November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium
Cedric Plachot, Lesley S Chaboub, Hibret A Adissu, Lei Wang, Albert Urazaev, Jennifer Sturgis, Elikplimi K Asem, Sophie A Lelievre
BMC Biology 2009, 7:77 (16November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor
Miryana Mircheva, Diana Boy, Benjamin Weiche, Friederike Hucke, Peter Graumann, Hans-Georg Koch
BMC Biology 2009, 7:76 (13November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2
Chang Liu, Dewald van Dyk, Yue Li, Brenda Andrews, Hai Rao
BMC Biology 2009, 7:75 (12November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A remarkable diversity of bone-eating worms (Osedax; Siboglinidae; Annelida)
Robert C Vrijenhoek, Shannon B Johnson, Greg W Rouse
BMC Biology 2009, 7:74 (10November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps
Jochen Trauner, Johannes Schinko, Marc D Lorenzen, Teresa D Shippy, Ernst A Wimmer, Richard W Beeman, Martin Klingler, Gregor Bucher, Susan J Brown
BMC Biology 2009, 7:73 (5November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Massively parallel tag sequencing reveals the complexity of anaerobic marine protistan communities
Thorsten Stoeck, Anke Behnke, Richard Christen, Linda Amaral-Zettler, Maria J Rodriguez-Mora, Andrei Chistoserdov, William Orsi, Virginia P Edgcomb
BMC Biology 2009, 7:72 (3November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The scent of supercolonies: the discovery, synthesis and behavioural verification of ant colony recognition cues
Miriam Brandt, Ellen van Wilgenburg, Robert Sulc, Kenneth J Shea, Neil D Tsutsui
BMC Biology 2009, 7:71 (28October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Genetical genomic determinants of alcohol consumption in rats and humans
Boris Tabakoff, Laura Saba, Morton Printz, Pam Flodman, Colin Hodgkinson, David Goldman, George Koob, Heather N Richardson, Katerina Kechris, Richard L Bell, Norbert Hbner, Matthias Heinig, Michal Pravenec, Jonathan Mangion, Lucie Legault, Maurice Dongier, Katherine M Conigrave, John B Whitfield, John Saunders, Bridget Grant, Paula L Hoffman, WHO/ISBRA Study on State and Trait Markers of Alcoholism
BMC Biology 2009, 7:70 (27October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest selected articles from BMC Medicine


This list contains articles from BMC Medicine that may be of interest to readers of BMC Biology

Research article
Oral high dose ascorbic acid treatment for one year in young CMT1A patients: a randomised, double-blind, placebo-controlled phase II trial
Camiel Verhamme, Rob J de Haan, Marinus Vermeulen, Frank Baas, Marianne de Visser, Ivo N van Schaik
BMC Medicine 2009, 7:70 (12November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect
Sean P Pitroda, Bassam T Wakim, Ravi F Sood, Mara G Beveridge, Michael A Beckett, Dhara M MacDermed, Ralph R Weichselbaum, Nikolai N Khodarev
BMC Medicine 2009, 7:68 (5November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease
Alessandra Pani, Antonella Mandas, Giacomo Diaz, Claudia Abete, Pier Luigi Cocco, Fabrizio Angius, Annalisa Brundu, Nico Muaka, Maria Elena Pais, Antonio Saba, Luigi Barberini, Cristina Zaru, Manuela Palmas, Paolo F Putzu, Alessandra Mocali, Francesco Paoletti, Paolo La Colla, Sandra Dess
BMC Medicine 2009, 7:66 (2November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Debate
Transforming medical professionalism to fit changing health needs
Thomas Plochg, Niek S Klazinga, Barbara Starfield
BMC Medicine 2009, 7:64 (26October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
Simon G Gregory, Jessica J Connelly, Aaron J Towers, Jessica Johnson, Dhani Biscocho, Christina A Markunas, Carla Lintas, Ruth K Abramson, Harry H Wright, Peter Ellis, Cordelia F Langford, Gordon Worley, G Robert Delong, Susan K Murphy, Michael L Cuccaro, Antonello Persico, Margaret A Pericak-Vance
BMC Medicine 2009, 7:62 (22October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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