BMC Biology is the flagship biology journal of the BMC series, publishing peer-reviewed research and methodology articles of special importance and broad interest in any area of biology, as well as reviews, opinion pieces, comment and Q&As on topics of special or topical interest.

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  • Miranda Robertson, BioMed Central

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    Evolutionary capacitance and evolvability

    Joanna Masel

    Joanna Masel explains how evolvability may be conferred by molecular "switches" that can expose cryptic mutations and allow selection to act on them, with the potential for adaptive changes in phenotype.

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    Natural genetic variation, proteostasis and aging

    Matt Kaeberlein

    Commenting on a study showing that genetic variation in wild strains of C. elegans modifies polyglutamine disease, Matt Kaeberlein explains why this nematode worm has proved a useful model for studying age-associated failures of protein homeostasis, and why the new research holds therapeutic promise.

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    The mathematics of HIV infection

    Alan Perelson, Ruy Ribeiro

    Alan Perelson and Ruy Ribeiro explain how differential equations that model the dynamics of HIV replication in its human host have led to important quantitative insights into the biology of HIV infection.

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    Big science, zombie projects, and what is really inside the cell

    Gregory Petsko

    Gregory Petsko, writing for the BMC Biology tenth birthday Open questions series, argues, with his usual forthrightness, that we need to pay more attention to where the balance of ‘big’ and ‘little’ science is going, and remember how little we know about the interior of the cell.

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Journal of Biology

BMC Biology assimilated the philosophy and distinguished Editorial Board and history of its sister journal Journal of Biology on fusion of the two journals in 2010. The full archive of Journal of Biology is available from its own archive website, and the objectives and aspirations of the combined journal are explained in the editorial that accompanied the fusion.

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ISSN: 1741-7007