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	1. 3666 Accesses	Research article A comparison of methods for differential expression analysis of RNA-seq data Charlotte Soneson, Mauro Delorenzi BMC Bioinformatics 2013, 14:91 (9 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	2. 2317 Accesses	Software 4273π: Bioinformatics education on low cost ARM hardware Daniel Barker, David EK Ferrier, Peter WH Holland, John BO Mitchell, Heleen Plaisier, Michael G Ritchie, Steven D Smart BMC Bioinformatics 2013, 14:243 (12 August 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary An open access, open learning method for teaching bioinformatics uses the Raspberry Pi computer and a custom operating system to teach early-career researchers key skills in systems administration and computational biology at low cost.
	3. 2168 Accesses	Methodology article Levenshtein error-correcting barcodes for multiplexed DNA sequencing Tilo Buschmann, Leonid V Bystrykh BMC Bioinformatics 2013, 14:272 (11 September 2013) Abstract \| Provisional PDF \| PubMed
	4. 2080 Accesses	Software NPEBseq: nonparametric empirical bayesian-based procedure for differential expression analysis of RNA-seq data Yingtao Bi, Ramana V Davuluri BMC Bioinformatics 2013, 14:262 (27 August 2013) Abstract \| Full text \| PDF \| PubMed
	5. 1747 Accesses	Methodology article Statistical analysis of real-time PCR data Joshua S Yuan, Ann Reed, Feng Chen, C Neal Stewart BMC Bioinformatics 2006, 7:85 (22 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 1706 Accesses	Software RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome Bo Li, Colin N Dewey BMC Bioinformatics 2011, 12:323 (4 August 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary RSEM is a new user-friendly software tool for quantifying transcript abundance from RNA-seq data that does not rely on a reference genome and is particularly useful for quantification with de novo transcriptome assemblies
	7. 1529 Accesses	Research article Comparing a few SNP calling algorithms using low-coverage sequencing data Xiaoqing Yu, Shuying Sun BMC Bioinformatics 2013, 14:274 (17 September 2013) Abstract \| Full text \| PDF \| PubMed
	8. 1517 Accesses	Software inTB - a data integration platform for molecular and clinical epidemiological analysis of tuberculosis Patrícia Soares, Renato J Alves, Ana B Abecasis, Carlos Penha-Gonçalves, M Gabriela M Gomes, José B Pereira-Leal BMC Bioinformatics 2013, 14:264 (30 August 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	9. 1492 Accesses	Research article Centroid based clustering of high throughput sequencing reads based on n-mer counts Alexander Solovyov, W Lipkin BMC Bioinformatics 2013, 14:268 (8 September 2013) Abstract \| Full text \| PDF \| PubMed
	10. 1465 Accesses	Methodology article Ontology based molecular signatures for immune cell types via gene expression analysis Terrence F Meehan, Nicole A Vasilevsky, Christopher J Mungall, David S Dougall, Melissa A Haendel, Judith A Blake, Alexander D Diehl BMC Bioinformatics 2013, 14:263 (30 August 2013) Abstract \| Full text \| PDF \| PubMed
	11. 1443 Accesses	Software WGCNA: an R package for weighted correlation network analysis Peter Langfelder, Steve Horvath BMC Bioinformatics 2008, 9:559 (29 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| f1000
	12. 1433 Accesses	Software AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides Oscar Conchillo-Solé, Natalia S de Groot, Francesc X Avilés, Josep Vendrell, Xavier Daura, Salvador Ventura BMC Bioinformatics 2007, 8:65 (27 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 1391 Accesses	Methodology article Efficient alignment of RNA secondary structures using sparse dynamic programming Cuncong Zhong, Shaojie Zhang BMC Bioinformatics 2013, 14:269 (8 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	14. 1266 Accesses	Methodology article A balanced iterative random forest for gene selection from microarray data Ali Anaissi, Paul J Kennedy, Madhu Goyal, Daniel R Catchpoole BMC Bioinformatics 2013, 14:261 (27 August 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	15. 1262 Accesses	Methodology article A flexible count data model to fit the wide diversity of expression profiles arising from extensively replicated RNA-seq experiments Mikel Esnaola, Pedro Puig, David Gonzalez, Robert Castelo, Juan R Gonzalez BMC Bioinformatics 2013, 14:254 (21 August 2013) Abstract \| Full text \| PDF \| PubMed
	16. 1253 Accesses	Research article Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments James H Bullard, Elizabeth Purdom, Kasper D Hansen, Sandrine Dudoit BMC Bioinformatics 2010, 11:94 (18 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 1160 Accesses	Research article Learning a Markov Logic network for supervised gene regulatory network inference Céline Brouard, Christel Vrain, Julie Dubois, David Castel, Marie-Anne Debily, Florence d’Alché-Buc BMC Bioinformatics 2013, 14:273 (12 September 2013) Abstract \| Full text \| PDF \| PubMed
	18. 1113 Accesses	Research article The COG database: an updated version includes eukaryotes Roman L Tatusov, Natalie D Fedorova, John D Jackson, Aviva R Jacobs, Boris Kiryutin, Eugene V Koonin, Dmitri M Krylov, Raja Mazumder, Sergei L Mekhedov, Anastasia N Nikolskaya, B Sridhar Rao, Sergei Smirnov, Alexander V Sverdlov, Sona Vasudevan, Yuri I Wolf, Jodie J Yin, Darren A Natale BMC Bioinformatics 2003, 4:41 (11 September 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| f1000
	19. 1096 Accesses	Research article Large-scale extraction of accurate drug-disease treatment pairs from biomedical literature for drug repurposing Rong Xu, QuanQiu Wang BMC Bioinformatics 2013, 14:181 (6 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	20. 1085 Accesses	Software A multiple-alignment based primer design algorithm for genetically highly variable DNA targets Johanna Brodin, Mohan Krishnamoorthy, Gayathri Athreya, Will Fischer, Peter Hraber, Cheryl Gleasner, Lance Green, Bette Korber, Thomas Leitner BMC Bioinformatics 2013, 14:255 (21 August 2013) Abstract \| Full text \| PDF \| PubMed
	21. 1083 Accesses	Research article Benchmarking short sequence mapping tools Ayat Hatem, Doruk Bozdağ, Amanda E Toland, Ümit V Çatalyürek BMC Bioinformatics 2013, 14:184 (7 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A benchmarking suite to analyze well-known next generation sequencing tools, mapping short reads to a reference genome, with respect to various technological and algorithmic perspectives and addressing issues using multiple approaches such as multiple simulators.
	22. 1074 Accesses	Software Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction Jian Ye, George Coulouris, Irena Zaretskaya, Ioana Cutcutache, Steve Rozen, Thomas L Madden BMC Bioinformatics 2012, 13:134 (18 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 1070 Accesses	Research article μHEM for identification of differentially expressed miRNAs using hypercuboid equivalence partition matrix Sushmita Paul, Pradipta Maji BMC Bioinformatics 2013, 14:266 (4 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	24. 1027 Accesses	Software Pathway-PDT: a flexible pathway analysis tool for nuclear families Yo Park, Michael Schmidt, Eden R Martin, Margaret A Pericak-Vance, Ren-Hua Chung BMC Bioinformatics 2013, 14:267 (4 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	25. 1010 Accesses	Software RCircos: an R package for Circos 2D track plots Hongen Zhang, Paul Meltzer, Sean Davis BMC Bioinformatics 2013, 14:244 (10 August 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed