Most Recent Articles: BMC Bioinformaticshttps://bmcbioinformatics.biomedcentral.comMost Recent Articles: BMC BioinformaticsQNetDiff: a quantitative measurement of network rewiringhttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05702-zBacteria in the human body, particularly in the large intestine, are known to be associated with various diseases. To identify disease-associated bacteria (markers), a typical method is to statistically compar...ResearchMon, 18 Mar 2024 00:00:00 GMThttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05702-zShota Nose, Hirotsugu Shiroma, Takuji Yamada and Yushi Uno2024-03-18T00:00:00ZDifferential network connectivity analysis for microbiome data adjusted for clinical covariates using jackknife pseudo-valueshttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05689-7A recent breakthrough in differential network (DN) analysis of microbiome data has been realized with the advent of next-generation sequencing technologies. The DN analysis disentangles the microbial co-abunda...ResearchMon, 18 Mar 2024 00:00:00 GMThttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05689-7Seungjun Ahn and Somnath Datta2024-03-18T00:00:00ZIntegration of scRNA-seq data by disentangled representation learning with condition domain adaptationhttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05706-9The integration of single-cell RNA sequencing data from multiple experimental batches and diverse biological conditions holds significant importance in the study of cellular heterogeneity.ResearchSat, 16 Mar 2024 00:00:00 GMThttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05706-9Renjing Liu, Kun Qian, Xinwei He and Hongwei Li2024-03-16T00:00:00ZUsing protein language models for protein interaction hot spot prediction with limited datahttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05737-2Protein language models, inspired by the success of large language models in deciphering human language, have emerged as powerful tools for unraveling the intricate code of life inscribed within protein sequen...ResearchSat, 16 Mar 2024 00:00:00 GMThttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05737-2Karen Sargsyan and Carmay Lim2024-03-16T00:00:00ZeSVD-DE: cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddingshttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05724-7Single-cell RNA-sequencing (scRNA) datasets are becoming increasingly popular in clinical and cohort studies, but there is a lack of methods to investigate differentially expressed (DE) genes among such datase...ResearchFri, 15 Mar 2024 00:00:00 GMThttps://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05724-7Kevin Z. Lin, Yixuan Qiu and Kathryn Roeder2024-03-15T00:00:00Z