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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Tim Sands PhD


Welcome to BMC Bioinformatics published by BioMed Central
BMC Bioinformatics is an open access journal publishing original peer-reviewed research articles in all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology. BMC Bioinformatics (ISSN 1471-2105) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.



BMC Featured articles

Darwin's picture, source Wikipedia
BMC Bioinformatics 2009, 10:S6
Scratchpads, a new social networking tool for natural history researchers and enthusiasts, links information from disparate sources, encourages data sharing, and promotes the ultimate goal of describing and synthesising all facets of the diversity of life.
Adapted from Wikipedia (JWSchmidt)
BMC Bioinformatics 2009, 10:350
Methods for quantifying cellcell contact often rely on global descriptors, such as overall cell density, but a new statistical model that accounts for local interactions, such as individual cell-cell distances, reduces noisy data and effectively describes contact inhibition effects.
Wikipedia
BMC Bioinformatics 2009, 10:342
IQuantitator is a sophisticated and novel software package, which uses a statistical inference approach to integrate multiple iTRAQ experiments, allowing users to estimate changes in protein expression levels under various treatment conditions
Image copyright Javier Rios and colleagues
BMC Bioinformatics 2009, 10:334
Magellanes is a discovery engine that searches the web for bioinformatics services and organizes them into workflows using a semantic approach.
BMC Bioinformatics 2009, 10:324
KEGGconverter offers users a single workflow software which merges selected KGML pathway files into a fully functional metabolic network SBML model, enhanced with default kinetics, and ready for simulation purposes.


BMC  Latest supplements published in BMC Bioinformatics


Volume 10 Suppl 14
Research

Volume 10 Suppl 13
Meeting abstracts
Stockholm, Sweden. 27 June 2009

Volume 10 Suppl 12
Research
Varenna, Italy. 1921 May 2008





BMC  Latest articles published in BMC Bioinformatics        [more info]


Research article
Prediction of protein binding sites in protein structures using hidden Markov support vector machine
Bin Liu, Xiaolong Wang, Lei Lin, Buzhou Tang, Qiwen Dong, Xuan Wang
BMC Bioinformatics 2009, 10:381 (20November2009)
[Abstract] [Provisional PDF]

Methodology article
An experimental loop design for the detection of constitutional chromosomal aberrations by array CGH
Joke Allemeersch, Steven Van Vooren, Femke Hannes, Bart De Moor, Joris Robert Vermeesch, Yves Moreau
BMC Bioinformatics 2009, 10:380 (19November2009)
[Abstract] [Provisional PDF]

Software
SitesIdentify: a protein functional site prediction tool
Tracey Bray, Pedro Chan, Salim Bougouffa, Richard Greaves, Andrew J Doig, Jim Warwicker
BMC Bioinformatics 2009, 10:379 (18November2009)
[Abstract] [Provisional PDF]

Methodology article
Nonlinear preprocessing method for detecting peaks from gas chromatograms
Byonghyo Shim, Hyeyoung Min, Sungroh Yoon
BMC Bioinformatics 2009, 10:378 (18November2009)
[Abstract] [Provisional PDF]

Methodology article
The ontology of biological sequences
Robert Hoehndorf, Janet Kelso, Heinrich Herre
BMC Bioinformatics 2009, 10:377 (18November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
Algorithms for effective querying of compound graph-based pathway databases
Ugur Dogrusoz, Ahmet Cetintas, Emek Demir, Ozgun Babur
BMC Bioinformatics 2009, 10:376 (16November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
A generic algorithm for layout of biological networks
Falk Schreiber, Tim Dwyer, Kim Marriott, Michael Wybrow
BMC Bioinformatics 2009, 10:375 (12November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Linguistic feature analysis for protein interaction extraction
Timur Fayruzov, Martine De Cock, Chris Cornelis, Veronique Hoste
BMC Bioinformatics 2009, 10:374 (12November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
A theoretical approach to spot active regions in antimicrobial proteins
Marc Torrent, Victria M Nogus, Ester Boix
BMC Bioinformatics 2009, 10:373 (11November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Illumina WG-6 BeadChip strips should be normalized separately
Wei Shi, Ashish Banerjee, Matthew E Ritchie, Steve Gerondakis, Gordon K Smyth
BMC Bioinformatics 2009, 10:372 (11November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Genome-wide analysis of major intrinsic proteins in the tree plant Populus trichocarpa: Characterization of XIP subfamily of aquaporins from evolutionary perspective
Anjali B. Gupta, Ramasubbu Sankararamakrishnan
BMC Plant Biology 2009, 9:134 (20November2009)
[Abstract] [Provisional PDF]

Software
Searching for SNPs with cloud computing
Ben Langmead, Michael C Schatz, Jimmy Lin, Mihai Pop, Steven L Salzberg
Genome Biology 2009, 10:R134 (20November2009)
[Abstract] [Provisional PDF]

Method
COMIT: Identification of noncoding motifs under selection in coding sequences
Deniz Kural, Yang Ding, Jiantao Wu, Alicia Korpi, Jeffrey H Chuang
Genome Biology 2009, 10:R133 (20November2009)
[Abstract] [Provisional PDF]

Methodology
HAMSTER: visualizing microarray experiments as a set of minimum spanning trees
Raymond Wan, Larisa Kiseleva, Hajime Harada, Hiroshi Mamitsuka, Paul Horton
Source Code for Biology and Medicine 2009, 4:8 (20November2009)
[Abstract] [Provisional PDF]

Research article
Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells
Yuko Saeki, Takaho Endo, Kaori Ide, Takeshi Nagashima, Noriko Yumoto, Tetsuro Toyoda, Harukazu Suzuki, Yoshihide Hayashizaki, Yoshiyuki Sakaki, Mariko Okada-Hatakeyama
BMC Genomics 2009, 10:545 (20November2009)
[Abstract] [Provisional PDF]

Research article
Differentially expressed genes for aggressive pecking behaviour in laying hens
Bart Buitenhuis, Jakob Hedgaard, Luc Janss, Peter Sorensen
BMC Genomics 2009, 10:544 (19November2009)
[Abstract] [Provisional PDF]

Research
Exceptional error minimization in putative primordial genetic codes
Artem S Novozhilov, Eugene V Koonin
Biology Direct 2009, 4:44 (19November2009)
[Abstract] [Provisional PDF]

Research
Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
Alison K. Bauer, Jennifer Fostel, Laura M. Degraff, Elizabeth A. Rondini, Christopher Walker, Sherry F. Grissom, Julie Foley, Steven R. Kleeberger
Molecular Cancer 2009, 8:107 (19November2009)
[Abstract] [Provisional PDF]

Commentary
Make it better but don't change anything
Jerry M Wright
Automated Experimentation 2009, 1:5 (19November2009)
[Abstract] [Provisional PDF]

Research
CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features
Kobby Essien, Sebastien Vigneau, Sofia Apreleva, Larry N Singh, Marisa S Bartolomei, Sridhar Hannenhalli
Genome Biology 2009, 10:R131 (18November2009)
[Abstract] [Provisional PDF]

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