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Cellular and membrane biochemistry

This section incorporates all aspects of cellular and membrane biochemistry, including but not limited to: cell signaling and trafficking, chemical biology of the cell, membrane proteins and energy transduction, and macromolecular chemistry.

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1.

Research article   Open Access Highly Accessed

Metazoan-like signaling in a unicellular receptor tyrosine kinase

Kira P Schultheiss, Barbara P Craddock, Michael Tong, Markus Seeliger, W Todd Miller BMC Biochemistry 2013, 14:4 (12 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

RTKB2 kinase from the unicellular choanoflagellate Monosiga brevicollis demonstrates regulatory functions as complex as those performed by mammalian receptor tyrosine kinases (RTKs), showing that complex signal transduction circuitry predates the evolution of metazoans.

2.

Research article   Open Access Highly Accessed

Presenilin-1 regulates the constitutive turnover of the fibronectin matrix in endothelial cells

Rita De Gasperi, Miguel A Gama Sosa, Gregory A Elder BMC Biochemistry 2012, 13:28 (21 December 2012)

Abstract | Full text | PDF | PubMed

3.

Research article   Open Access Highly Accessed

Arg188 in rice sucrose transporter OsSUT1 is crucial for substrate transport

Ye Sun, John M Ward BMC Biochemistry 2012, 13:26 (21 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Arginine-188 of the plant sucrose uptake transporter OsSUT1 is required for substrate translocation but not interaction, implicating the involvement of an alternative substrate binding site in substrate recognition.

4.

Research article   Open Access Highly Accessed

Proteomic analysis on N, N ′-dinitrosopiperazine-mediated metastasis of nasopharyngeal carcinoma 6-10B cells

Yuejin Li, Na Liu, Damao Huang, Zhenlin Zhang, Zhengke Peng, Chaojun Duan, Xiaowei Tang, Gongjun Tan, Guangrong Yan, Wenhua Mei, Faqing Tang BMC Biochemistry 2012, 13:25 (19 November 2012)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783

Wei Tian, Like Qu, Lin Meng, Caiyun Liu, Jian Wu, Chengchao Shou BMC Biochemistry 2012, 13:22 (23 October 2012)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access Highly Accessed

Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1

Juha Grönholm, Sari Vanhatupa, Daniela Ungureanu, Jouni Väliaho, Tuomo Laitinen, Jarkko Valjakka, Olli Silvennoinen BMC Biochemistry 2012, 13:20 (8 October 2012)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access Highly Accessed

Identification of avian wax synthases

Eva-Maria Biester, Janine Hellenbrand, Jens Gruber, Mats Hamberg, Margrit Frentzen BMC Biochemistry 2012, 13:4 (4 February 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Homology searching of avian databases has identified wax synthase genes expressed in the bird preen gland; analysis of the expressed proteins confirms they are capable of catalysing wax synthesis.

8.

Research article   Open Access

Hyaluronan synthase mediates dye translocation across liposomal membranes

Andria P Medina, Jialing Lin, Paul H Weigel BMC Biochemistry 2012, 13:2 (25 January 2012)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I

Mohammad A Hossain, Sereyrath Ngeth, Teddy Chan, Michael N Oda, Gordon A Francis BMC Biochemistry 2012, 13:1 (16 January 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Lipid-bound apolipoproteins on the surface of spherical high density lipoprotein (HDL) particles can behave like lipid-free apolipoprotein A-I (apoA-I) to increase ATP-binding cassette transporter A1 (ABCA1) protein levels and activity.

10.

Research article   Open Access Highly Accessed

Fatty acyl-CoA reductases of birds

Janine Hellenbrand, Eva-Maria Biester, Jens Gruber, Mats Hamberg, Margrit Frentzen BMC Biochemistry 2011, 12:64 (12 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Fatty acyl-CoA reductases (FARs) cloned from the preening glands of barn owls, chickens and geese represent two distinct groups of isozymes that may be involved in wax ester biosynthesis and other pathways such as ether lipid synthesis

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