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Revalidation and rationale for high pKa values of unconjugated bilirubin
J Donald Ostrow, Pasupati Mukerjee BMC Biochemistry 2007, 8:7 (2 May 2007)
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Mapping of possible prion protein self-interaction domains using peptide arrays
Alan Rigter, Jan PM Langeveld, Drophatie Timmers-Parohi, Jorg G Jacobs, Peter LJM Moonen, Alex Bossers BMC Biochemistry 2007, 8:6 (12 April 2007)
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Editor’s summary
Peptide arrays reveal several distinct binding sequences for self-interactions between prion proteins, sequences in which variation affects binding patterns and may lead to strain differences in prion disease.
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p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts
Yuichi Tsuchiya, Shigeru Yamashita BMC Biochemistry 2007, 8:5 (11 April 2007)
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A novel bifunctional N-acetylglutamate synthase-kinase from Xanthomonas campestris that is closely related to mammalian N-acetylglutamate synthase
Qiuhao Qu, Hiroki Morizono, Dashuang Shi, Mendel Tuchman, Ljubica Caldovic BMC Biochemistry 2007, 8:4 (10 April 2007)
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Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa
Isaac M Westwood, Edith Sim BMC Biochemistry 2007, 8:3 (20 March 2007)
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Expression and localization of estrogenic type 12 17β-hydroxysteroid dehydrogenase in the cynomolgus monkey
Hong Liu, ShuFang Zheng, Véronique Bellemare, Georges Pelletier, Fernand Labrie, Van Luu-The BMC Biochemistry 2007, 8:2 (5 February 2007)
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Effect of polyamines and synthetic polyamine-analogues on the expression of antizyme (AtoC) and its regulatory genes
Panagiota S Filippou, Efthimia E Lioliou, Christos A Panagiotidis, Constantinos M Athanassopoulos, Thomas Garnelis, Dionyssios Papaioannou, Dimitrios A Kyriakidis BMC Biochemistry 2007, 8:1 (15 January 2007)
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Acyl-CoA-binding and self-associating properties of a recombinant 13.3 kDa N-terminal fragment of diacylglycerol acyltransferase-1 from oilseed rape
Randall J Weselake, Milan Madhavji, Steve J Szarka, Nii A Patterson, William B Wiehler, Cory L Nykiforuk, Tracy L Burton, Parveen S Boora, Steven C Mosimann, Nora A Foroud, Benjamin J Thibault, Maurice M Moloney, André Laroche, Tara L Furukawa-Stoffer BMC Biochemistry 2006, 7:24 (27 December 2006)
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Characterization of a β-glucanase produced by Rhizopus microsporus var. microsporus, and its potential for application in the brewing industry
Klecius Celestino, Ricardo B Cunha, Carlos R Felix BMC Biochemistry 2006, 7:23 (5 December 2006)
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Limited proteolysis of human histone deacetylase 1
Nayana Kamath, Paulina Karwowska-Desaulniers, Mary Kay H Pflum BMC Biochemistry 2006, 7:22 (5 October 2006)
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The DNA polymerase activity of Pol ε holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts
Koh Shikata, Taro Sasa-Masuda, Yukiko Okuno, Shou Waga, Akio Sugino BMC Biochemistry 2006, 7:21 (22 August 2006)
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Identification, cloning and characterization of a novel 47 kDa murine PKA C subunit homologous to human and bovine Cβ2
Ane Funderud, Heidi H Henanger, Tilahun T Hafte, Paul S Amieux, Sigurd Ørstavik, Bjørn S Skålhegg BMC Biochemistry 2006, 7:20 (4 August 2006)
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Editor’s summary
Protein kinase A catalytic subunit terminology in mice has been aligned to that of humans: a newly discovered mouse lymph-specific splice variant is designated cbeta2 and the brain-expressed isoform is now called cbeta4.
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Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation – molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor
Akira Higashibata, Mari Imamizo-Sato, Masaya Seki, Takashi Yamazaki, Noriaki Ishioka BMC Biochemistry 2006, 7:19 (28 June 2006)
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Editor’s summary
Simulated microgravity disrupts actin fibers, and is now shown to downregulate a Rho guanine nucleotide exchange factor and repress Rho GTPase activity in bovine endothelial cells, implicating this pathway in the transduction of gravitational signals.
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Benchmarking pKa prediction
Matthew N Davies, Christopher P Toseland, David S Moss, Darren R Flower BMC Biochemistry 2006, 7:18 (2 June 2006)
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Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle
Simone Badal, Paul D Brown, Dalip Ragoobirsingh BMC Biochemistry 2006, 7:17 (27 May 2006)
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Editor’s summary
Nitric oxide (NO) donors reduce insulin receptor-beta levels and alter phosphorylation of insulin receptor substrate-1 in rat skeletal muscle cells, suggesting that NO induces insulin resistance by regulating insulin-mediated signal transduction.
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Identification of a Bacillus thuringiensis Cry11Ba toxin-binding aminopeptidase from the mosquito, Anopheles quadrimaculatus
Mohd Abdullah, Algimantas P Valaitis, Donald H Dean BMC Biochemistry 2006, 7:16 (22 May 2006)
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Calcium adsorption and displacement: characterization of lipid monolayers and their interaction with membrane-active peptides/proteins
Sven O Hagge, Malte U Hammer, Andre Wiese, Ulrich Seydel, Thomas Gutsmann BMC Biochemistry 2006, 7:15 (3 May 2006)
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Aquaporin-11: A channel protein lacking apparent transport function expressed in brain
Daniel A Gorelick, Jeppe Praetorius, Takashi Tsunenari, Søren Nielsen, Peter Agre BMC Biochemistry 2006, 7:14 (1 May 2006)
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Editor’s summary
Although mammalian aquaporin-11 is related to integral membrane transport proteins, it lacks a transport function when expressed in Xenopus oocyte plasma membranes and localizes intracellularly within neurons, so it may represent a functionally distinct subfamily.
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Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-α-acetyltransferase
Thomas Arnesen, Matthew J Betts, Frédéric Pendino, David A Liberles, Dave Anderson, Jaime Caro, Xianguo Kong, Jan E Varhaug, Johan R Lillehaug BMC Biochemistry 2006, 7:13 (25 April 2006)
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Editor’s summary
The discovery of a gene, human Arrest defective 2 (hARD2), that may complement the function of its homolog hARD1 and interact with the N-acetyltransferase NATH, highlights the potential complexity of protein N-alpha-acetylation in mammals.
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The effect of engineered disulfide bonds on the stability of Drosophila melanogaster acetylcholinesterase
Omid Siadat, Andrée Lougarre, Lucille Lamouroux, Caroline Ladurantie, Didier Fournier BMC Biochemistry 2006, 7:12 (16 April 2006)
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The PLAC1-homology region of the ZP domain is sufficient for protein polymerisation
Luca Jovine, William G Janssen, Eveline S Litscher, Paul M Wassarman BMC Biochemistry 2006, 7:11 (6 April 2006)
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Editor’s summary
The N-terminal of the zona pellucida domain is sufficient to enable a protein to fold and form filaments, suggesting only this half is critical for polymerization and that the C-terminal domain plays a regulatory role.
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Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain
Santiago Cal, Juan R Peinado, María Llamazares, Víctor Quesada, Angela Moncada-Pazos, Cecilia Garabaya, Carlos López-Otín BMC Biochemistry 2006, 7:9 (27 March 2006)
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Editor’s summary
Polyserase-3, a novel secretory, non-glycosylated serine protease containing two tandem protease domains, is catalytically active as a dimer, and although sharing some features with other human polyserases, it has a unique expression pattern.
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EAAC1 is expressed in rat and human prostate epithelial cells; functions as a high-affinity L-aspartate transporter; and is regulated by prolactin and testosterone
Renty B Franklin, Jing Zou, Ziqiang Yu, Les C Costello BMC Biochemistry 2006, 7:10 (27 March 2006)
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Editor’s summary
Previously known only as a glutamate transporter, EAAC1 is now identified as the main aspartate uptake system in rat and human prostate epithelial cells under testosterone and prolactin regulation.
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Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomics
Joachim Füllekrug, Anna Shevchenko, Andrej Shevchenko, Kai Simons BMC Biochemistry 2006, 7:8 (13 March 2006)
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Editor’s summary
Two key epithelial polarity markers have been characterized by a combination of tandem mass spectrometry and homology based proteomics, an effective technique for identifying membrane proteins when no genome sequence is available.
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The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site
Katrin de Graaf, Hanna Czajkowska, Sabine Rottmann, Len C Packman, Richard Lilischkis, Bernhard Lüscher, Walter Becker BMC Biochemistry 2006, 7:7 (2 March 2006)
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