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Research article   Open Access

Proteomic analysis of differentially expressed proteins in vitamin C-treated AGS cells

Arulkumar Nagappan, Hyeon Park, Kwang Park, Jin A Kim, Gyeong Hong, Sang Kang, Jue Zhang, Eun Kim, Won Lee, Chung Won, Gon Kim BMC Biochemistry 2013, 14:24 (26 September 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

A highly conserved arginine residue of the chitosanase from Streptomyces sp. N174 is involved both in catalysis and substrate binding

Marie-Ève Lacombe-Harvey, Mélanie Fortin, Takayuki Ohnuma, Tamo Fukamizo, Thomas Letzel, Ryszard Brzezinski BMC Biochemistry 2013, 14:23 (16 September 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Functional redundancy between trans-Golgi network SNARE family members in Arabidopsis thaliana

Sang-Jin Kim, Diane C Bassham BMC Biochemistry 2013, 14:22 (11 September 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

A proteoliposome fusion assay provides evidence for functional overlap between members of the SYP4 and VTI1 groups of Arabidopsis thaliana SNARE proteins in membrane fusion, in support of previously published genetic data.

Research article   Open Access Highly Accessed

Newly developed TGF-β2 knock down transgenic mouse lines express TGF-β2 differently and its distribution in multiple tissues varies

Yan-Bin XiYang, Fang Wang, Bao-Jiang Qian, Ling You, Bing-Tuan Lu, Wei Zhang, Xiong-Zhi Quan, Wen-Ping Ge, Su Liu, Lian-Feng Zhang, Ting-Hua Wang BMC Biochemistry 2013, 14:21 (6 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

TNFa alter cholesterol metabolism in human macrophages via PKC-θ-dependent pathway

A Sha Ma, Qian Zhang, Zhi Song BMC Biochemistry 2013, 14:20 (3 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants: hydroxylation of 1-methoxynaphthalene

James E Erman, Heather Kilheeney, Anil K Bidwai, Caitlan E Ayala, Lidia B Vitello BMC Biochemistry 2013, 14:19 (30 July 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Mutating Arg48, Trp51, and His52 in the distal heme pocket of cytochrome C peroxidase to alanines improves the binding affinity of apolar substrates and escalates turnover rate, though the constructs are more susceptible to oxidative degradation.

Research article   Open Access Highly Accessed

Identification of the lamin A/C phosphoepitope recognized by the antibody P-STM in mitotic HeLa S3 cells

Jeng-Ting Chen, Chia-Wen Ho, Lang-Ming Chi, Kun-Yi Chien, Ya-Ju Hsieh, Shih-Jie Lin, Jau-Song Yu BMC Biochemistry 2013, 14:18 (19 July 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Transcription start sites and epigenetic analysis of the HSD17B10 proximal promoter

Song-Yu Yang, Carl Dobkin, Xue-Ying He, W Brown BMC Biochemistry 2013, 14:17 (8 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Experimental detection of proteolytic activity in a signal peptide peptidase of Arabidopsis thaliana

Masako Hoshi, Yu Ohki, Keisuke Ito, Taisuke Tomita, Takeshi Iwatsubo, Yoshiro Ishimaru, Keiko Abe, Tomiko Asakura BMC Biochemistry 2013, 14:16 (6 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Probing the stability of the “naked” mucin-like domain of human α-dystroglycan

Manuela Bozzi, Enrico Di Stasio, Giovanni Scaglione, Claudia Desiderio, Claudia Martelli, Bruno Giardina, Francesca Sciandra, Andrea Brancaccio BMC Biochemistry 2013, 14:15 (1 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

Editorial   Open Access Highly Accessed

Interview with Sabato D’Auria, Section Editor for the Chemical Biology section in BMC Biochemistry

Sabato D’Auria BMC Biochemistry 2013, 14:14 (14 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a activation and inhibit lipolysis

Héctor Vázquez-Meza, Martha de Piña, Juan Pardo, Héctor Riveros-Rosas, Rafael Villalobos-Molina, Enrique Piña BMC Biochemistry 2013, 14:13 (30 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Cell attachment on poly(3-hydroxybutyrate)-poly(ethylene glycol) copolymer produced by Azotobacter chroococcum 7B

Anton P Bonartsev, Sergey G Yakovlev, Irina I Zharkova, Arasha P Boskhomdzhiev, Dmitrii V Bagrov, Vera L Myshkina, Tatiana K Makhina, Elena P Kharitonova, Olga V Samsonova, Alexey V Feofanov, Vera V Voinova, Anton L Zernov, Yurii M Efremov, Garina A Bonartseva, Konstantin V Shaitan, Michail P Kirpichnikov BMC Biochemistry 2013, 14:12 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Construction of a chimeric thermoacidophilic beta-endoglucanase

Kristina Kufner, Georg Lipps BMC Biochemistry 2013, 14:11 (29 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Targeted combination of cellulases from Sulfolobus solfataricus and Thermotoga maritima results in a chimera that displays advantageous qualities from both parent enzymes, suggesting that this technique could act as an alternative to point mutational engineering.

Research article   Open Access

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription

Daniel Abankwa, Susan M Millard, Nick Martel, Catherine S Choong, Miao Yang, Lisa M Butler, Grant Buchanan, Wayne D Tilley, Nobuhide Ueki, Michael J Hayman, Gary M Leong BMC Biochemistry 2013, 14:10 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Side chain requirements for affinity and specificity in D5, an HIV-1 antibody derived from the VH1-69 germline segment

Alex Stewart, Joseph S Harrison, Lauren K Regula, Jonathan R Lai BMC Biochemistry 2013, 14:9 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

Reviewer acknowledgement   Open Access Highly Accessed

Annual acknowledgement of manuscript reviewers

Emilie Aime BMC Biochemistry 2013, 14:7 (21 March 2013)

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Research article   Open Access Highly Accessed

Nedd8 processing enzymes in Schizosaccharomyces pombe

Jean E O’Donoghue, Dawadschargal Bech-Otschir, Ida B Larsen, Mairi Wallace, Rasmus Hartmann-Petersen, Colin Gordon BMC Biochemistry 2013, 14:8 (15 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand

Amanda J Boyle, Leigh Ann Roddick, Varsha Bhakta, Melissa D Lambourne, Murray S Junop, Patricia C Liaw, Jeffrey I Weitz, William P Sheffield BMC Biochemistry 2013, 14:6 (7 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An isolated form of N-terminal acidic extension of Heparin cofactor II (HCII 1-75) binds thrombin with a higher affinity than glycosaminoglycans (GAGs), suggesting that this region of Heparin cofactor II (HCII) is required for binding of thrombin exosite 1.

Research article   Open Access Highly Accessed

Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7

Meng Xu, Y Paul Chang, Xiaojiang S Chen BMC Biochemistry 2013, 14:5 (27 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Metazoan-like signaling in a unicellular receptor tyrosine kinase

Kira P Schultheiss, Barbara P Craddock, Michael Tong, Markus Seeliger, W Todd Miller BMC Biochemistry 2013, 14:4 (12 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

RTKB2 kinase from the unicellular choanoflagellate Monosiga brevicollis demonstrates regulatory functions as complex as those performed by mammalian receptor tyrosine kinases (RTKs), showing that complex signal transduction circuitry predates the evolution of metazoans.

Hypothesis   Open Access Highly Accessed

Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor

Vic Norris, Patrick Amar, Guillaume Legent, Camille Ripoll, Michel Thellier, Judit Ovádi BMC Biochemistry 2013, 14:3 (11 February 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Hepatoma-derived growth factor and nucleolin exist in the same ribonucleoprotein complex

Stephanie Bremer, Katharina Klein, Angela Sedlmaier, Mekky Abouzied, Volkmar Gieselmann, Sebastian Franken BMC Biochemistry 2013, 14:2 (10 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy

Saori Kobayashi, Noriko Yoneda-Kato, Nagisa Itahara, Akihiro Yoshida, Jun-ya Kato BMC Biochemistry 2013, 14:1 (6 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity

Meredith J Layton, Mirette Saad, Nicole L Church, Richard B Pearson, Christina A Mitchell, Wayne A Phillips BMC Biochemistry 2012, 13:30 (27 December 2012)

Abstract | Full text | PDF | PubMed

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