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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Biochemistry published by BioMed Central
BMC Biochemistry is an open access journal publishing original peer-reviewed research articles in all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.
BMC Biochemistry (ISSN 1471-2091) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
BMC Biochemistry 2009, 10 :27
The new version of the Cytochrome P450 Engineering Database (CYPED) contains information on the sequences of 8613 proteins and the structures of 47 proteins, and has been extended by integrating biochemical information from the Cytochrome P450 Knowledgebase.
BMC Biochemistry 2009, 10 :24
Our understanding of how SAPS-related proteins differentially regulate closely-related Ser/Thr phosphatases is advanced by a study indicating that human PP6R3 forms distinctive helical repeats within its conserved SAPS domain and uses interhelical loops to associate with protein phosphatase 6.
BMC Biochemistry 2009, 10 :23
Cathepsin cysteine proteases are active under conditions simulating extracellular and intracellular compartments with a range of pHs and redox potentials, as shown by cleavage of the natural substrate thyroglobulin in distinct ways in different physiologic environments.
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Research article
Purification and characterization of cysteine protease from germinating cotyledons of horse gram Rajeswari Jinka, Vadde Ramakrishna, Sridhar K Rao, Ramakrishna P Rao BMC Biochemistry 2009, 10 :28 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
The Cytochrome P450 Engineering Database: integration of biochemical properties Demet Sirim, Florian Wagner, Andrey Lisitsa, J BMC Biochemistry 2009, 10 :27 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate Christina Ramel, Micha Tobler, Martin Meyer, Laurent Bigler, Marc-Olivier Ebert, Barbara Schellenberg, Robert Dudler BMC Biochemistry 2009, 10 :26 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ser170 of Bacillus thuringiensis Cry1Ab Manduca sexta brush border membranes Oscar Alzate, Craig F Hemann, Cristina Osorio, Russ Hille, Donald H Dean BMC Biochemistry 2009, 10 :25 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Mapping of protein phosphatase-6 association with its SAPS domain regulatory subunit using a model of helical repeats Julien Guergnon, Urszula Derewenda, Jessica R Edelson, David L Brautigan BMC Biochemistry 2009, 10 :24 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions Silvia Jordans, Sa BMC Biochemistry 2009, 10 :23 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of a nuclear localization motif in the serine/arginine protein kinase PSRPK of physarum polycephalum Shide Liu, Zhuolong Zhou, Ziyang Lin, Qiuling Ouyang, Jianhua Zhang, Shengli Tian, Miao Xing BMC Biochemistry 2009, 10 :22 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Contribution of oenocytes and pheromones to courtship behaviour in Drosophila Claude Wicker-Thomas, Ilhem Guenachi, Youssouf F Keita BMC Biochemistry 2009, 10 :21 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Biochemical characterization of malate synthase G of P. aeruginosa Bart Roucourt, Nikki Minnebo, Patrick Augustijns, Kirsten Hertveldt, Guido Volckaert, Rob Lavigne BMC Biochemistry 2009, 10 :20 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity Po-Wen Chang, Amrita Madabushi, A-Lien Lu BMC Biochemistry 2009, 10 :19 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Prediction of protein binding sites in protein structures using hidden Markov support vector machine Bin Liu, Xiaolong Wang, Lei Lin, Buzhou Tang, Qiwen Dong, Xuan Wang BMC Bioinformatics 2009, 10 :381 (20 [Abstract ] [Provisional PDF ]
Research
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells Sara De Boo, Joanna Kopecka, Davide Brusa, Elena Gazzano, Lina Matera, Dario Ghigo, Amalia Bosia, Chiara Riganti Molecular Cancer 2009, 8 :108 (19 [Abstract ] [Provisional PDF ]
Research
Expression of complement system components during aging and amyloid deposition in APP transgenic mice Julia Reichwald, Simone Danner, Karl-Heinz Wiederhold, Matthias Staufenbiel Journal of Neuroinflammation 2009, 6 :35 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Reliability of measuring abductor hallucis muscle parameters using two different diagnostic ultrasound machines Wayne A Hing, Keith Rome, Aylse FM Cameron Journal of Foot and Ankle Research 2009, 2 :33 (16 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Doxorubicin Loaded Polymeric Nanoparticulate Delivery System to
Overcome Drug Resistance in Osteosarcoma
Michiro Susa, Arun K Iyer, Keinosuke Ryu, Francis J Hornicek, Henry Mankin, Mansoor M Amiji, Zhenfeng Duan BMC Cancer 2009, 9 :399 (16 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short Report
The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase Valnes S Rodrigues-Junior, Ardala Breda, Diogenes S Santos, Luiz A Basso BMC Research Notes 2009, 2 :227 (16 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies Prabhakar Rajan, Caroline Dalgliesh, Cyril F Bourgeois, Monika Heiner, Kaveh Emami, Emma L Clark, Albrecht Bindereif, James Stevenin, Craig N Robson, Hing Y Leung, David J Elliott BMC Cell Biology 2009, 10 :82 (13 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor Miryana Mircheva, Diana Boy, Benjamin Weiche, Friederike Hucke, Peter Graumann, Hans-Georg Koch BMC Biology 2009, 7 :76 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The effect of psychological stress on iron absorption in rats Jianbo Chen, Hui Shen, Chengjie Chen, Wanyin Wang, Siyu Yu, Min Zhao, Min Li BMC Gastroenterology 2009, 9 :83 (13 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
A luciferase based viability assay for ATP detection in 384- well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427 Melissa L Sykes, Vicky M Avery Parasites & Vectors 2009, 2 :54 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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