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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Biochemistry published by BioMed Central
BMC Biochemistry is an open access journal publishing original peer-reviewed research articles in all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.
BMC Biochemistry (ISSN 1471-2091) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
BMC Biochemistry 2010, 11 :9
A database of thiamine diphosphate (ThDP) dependent enzymes includes multisequence alignments and phylogenetic trees for families of the enzymes, structural information, and SNPs of human enzymes that might be related to disease.
BMC Biochemistry 2010, 11 :4
Amodiaquine inhibits the activity of Plasmodium falciparum phosphoethanolamine methyltransferase and, as this enzyme is essential for survival of the malaria parasite and is not found in mammals, the inhibitor is an ideal candidate for drug development.
BMC Biochemistry 2010, 11 :1
A bacterial homologue of the maize orthophosphate dikinase regulatory protein, cloned from Escherichia coli, catalyses both the inactivation and activation of phosphoenolpyruvate synthetase, by ADP-dependent phosphorylation, and Pi-dependent pyrophosphorylation respectively.
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Database
The Thiamine diphosphate dependent Enzyme Engineering Database: A tool for the systematic analysis of sequence and structure relations Michael Widmann, Robert Radloff, Jurgen Pleiss BMC Biochemistry 2010, 11 :9 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Orthophosphate binding at the dimer interface of Corynebacterium callunae starch phosphorylase: mutational analysis of its role for activity and stability of the enzyme Mario Mueller, Bernd Nidetzky BMC Biochemistry 2010, 11 :8 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
NMR characterisation of the minimal interacting regions of centrosomal proteins 4.1R and NuMA1: effect of phosphorylation Miguel A Trevino, Mar Rodriguez-Rodriguez, Isabel Correas, Miguel Marcilla, Juan P Albar, Manuel Rico, Maria ANGELES Jimenez, Marta Bruix BMC Biochemistry 2010, 11 :7 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity Sakihito Kitajima, Kaeko Kamei, Shigeru Taketani, Masamitsu Yamaguchi, Fumiko Kawai, Aino Komatsu, Yoshihiro Inukai BMC Biochemistry 2010, 11 :6 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples Sergio Goncalves, Vincent Paupe, Emmanuel P Dassa, Jean-Jacques Briere, Judith Favier, Anne-Paule Gimenez-Roqueplo, Paule Benit, Pierre Rustin BMC Biochemistry 2010, 11 :5 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay April M Bobenchik, Jae-Yeon Choi, Arunima Mishra, Iulian N Rujan, Bing Hao, Dennis R Voelker, Jeffrey C Hoch, Choukri Ben Mamoun BMC Biochemistry 2010, 11 :4 (19 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae Darren Greetham, Jill Vickerstaff, Daniel Shenton, Gabriel G Perrone, Ian W Dawes, Chris M Grant BMC Biochemistry 2010, 11 :3 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Mechanism of attenuation of leptin signaling under chronic ligand stimulation Holger Knobelspies, Julia Zeidler, Paul Hekerman, Simone Bamberg-Lemper, Walter Becker BMC Biochemistry 2010, 11 :2 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Cloning and characterization of Escherichia coli DUF299: a bifunctional ADP-dependent kinase - Pi -dependent pyrophosphorylase from bacteria Jim N Burnell BMC Biochemistry 2010, 11 :1 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of four novel phosphorylation sites in estrogen receptor Christopher C Williams, Aninda Basu, Abeer El-Gharbawy, Latonya M Carrier, Carolyn L Smith, Brian G Rowan BMC Biochemistry 2009, 10 :36 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Carbohydrate intake and cardiometabolic risk factors in high BMI African American children Sushma Sharma, Lindsay S Roberts, Robert H Lustig, Sharon E Fleming Nutrition & Metabolism 2010, 7 :10 (9 [Abstract ] [Provisional PDF ]
Research article
BDNF Val66Met polymorphism and protein levels in Amniotic Fluid Annamaria Cattaneo, Luisella Bocchio-Chiavetto, Roberta Zanardini, Eleonora Marchina, Daniela Bellotti, Elena Milanesi, Stefania Moraschi, Francesca Calabrese, Sergio Barlati, Marco Andrea Riva, Massimo Gennarelli BMC Neuroscience 2010, 11 :16 (8 [Abstract ] [Provisional PDF ]
Research article
Food seeking in spite of harmful consequences is under prefrontal cortical noradrenergic control Emanuele Claudio Latagliata, Enrico Patrono, Stefano Puglisi-Allegra, Rossella Ventura BMC Neuroscience 2010, 11 :15 (8 [Abstract ] [Provisional PDF ]
Research
Regulations of the key mediators in inflammation and atherosclerosis by Aspirin in human macrophages Li Lu, Hong Liu, Jiahe Peng, Lin Gan, Lili Shen, Qian Zhang, Liangpeng Li, Li Zhang, Chang Su, Yu Jiang Lipids in Health and Disease 2010, 9 :16 (6 [Abstract ] [Provisional PDF ]
Research
CD73 represses pro-inflammatory responses in human endothelial cells Jana KG Gruenewald, Anne J Ridley Journal of Inflammation 2010, 7 :10 (5 [Abstract ] [Provisional PDF ]
Review
Ceramide and ceramide 1-phosphate in health and disease Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba, Antonio Gomez-Munoz Lipids in Health and Disease 2010, 9 :15 (5 [Abstract ] [Provisional PDF ]
Research article
Mining protein loops using a structural alphabet and
statistical exceptionality Leslie Regad, Juliette Martin, Gregory Nuel, Anne-claude Camproux BMC Bioinformatics 2010, 11 :75 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion Siyi Hu, Nathalie Delorme, Zhenzhen Liu, Tao Liu, Cruz Velasco-Gonzalez, Jone Garai, Ashok Pullikuth, Shahriar Koochekpour Molecular Cancer 2010, 9 :30 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability Qifeng Jiang, Renjian Huang, Shaoxi Cai, Chih-Lueh A Wang Journal of Biomedical Science 2010, 17 :6 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short report
High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells Theresia R Kress, Thomas Raabe, Stephan M Feller Cell Communication and Signaling 2010, 8 :1 (2 [Abstract ] [Provisional PDF ] [1 comment ]
Featured articles
: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2