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Perioperative medicine and outcome

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Research article   Open Access Highly Accessed

Effect of remifentanil infusion rate on stress response in orthopedic surgery using a tourniquet application

Taketo Shinoda, Wakako Murakami, Yasuo Takamichi, Hiroki Iizuka, Masaaki Tanaka, Yuto Kuwasako BMC Anesthesiology 2013, 13:14 (10 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Higher doses of the analgesic Remifentanil , a standard in balanced anaesthesia, diminishes tourniquet-pain induced stress hormones including cortisol and ACTH, which may aid in stabilizing hemodynamic deviations, thereby improving surgical outcomes

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