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  • Wilms tumor biomarkers

    Methylome analysis of Wilms tumor identifies differentially methylated biomarker regions that can be detected in cell-free circulating DNA

    Genome Biology 2014, 15:434
  • Image attributed to: iStock photos

    Coping with diabetes in Latin America

    Latin American healthcare is straining to cope with chronic diseases such as diabetes; Armando Arredondo highlights the need for more resources to be allocated to preventive medicine, and discusses ways in which this may be achieved in these settings.

    BMC Medicine 2014, 12:136
  • Editorial

    An Editorial summing up our thematic series on 'Cilia assembly mechanisms'.  The full article collection can be accessed at

    Cilia 2014, 3:8
  • B-cell lymphoma relapse

    Sequencing of VDJ rearrangements and analysis of somatic hypermutations reveals two distinct clonal evolution modes in diffuse large B-cell lymphoma

    Genome Biology 2014, 15:432
  • Image attributed to: Peterson B Moose_Wikimedia commons

    Herbivore responses to a toxic diet

    Woodrat populations that have evolutionary experience of ingesting creosote toxins display similar biotransformation strategies compared to naïve populations, revealing key genes that are upregulated in response to a toxic diet.

    BMC Ecology 2014, 14:23
  • Insights into the neurobiology of itch

    New evidence contributing to our understanding of the neuropeptides critical for itch responses, with a look at the tissues in which these peptides are expressed and their positions in the itch circuit.

    Molecular Pain 2014, 10:44
  • Consultant cover and ICU mortality

    There is no relationship between days of continuous cover by a single intensivist and patient outcomes in adult, general ICUs in England but intensivist participation in handover is associated with increased mortality.

    Critical Care 2014, 18:491
  • Image attributed to: CC Flickr geezaweezer

    Mesalazine safe for malnourished children

    In a preliminary trial, mesalazine is safe for use in acutely malnourished children with severe environmental enteric dysfunction, indicating that further studies should target host inflammatory responses to treat these children

    BMC Medicine 2014, 12:133
  • Lung cancer lncRNAs

    Many lung cancer-associated lncRNAs and their role in tumorigenesis  are revealed in a transcriptional analysis

    Genome Biology 2014, 15:429
  • Is NGS ready for the clinic?

    Next-generation sequencing (NGS) provides a large amount of information about tumor genetics; in this forum article, breast cancer specialists debate whether NGS can guide clinical decision making, or whether it is not yet ready for routine use.

    BMC Medicine 2014, 12:140
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