Discussing a novel integrated approach to personalized medicine that begins with phenomic data, is stratified by genomics, and is ultimately refined by metabolomic pathway data.
Occupational social class and educational level are associated with serum lipid levels and the relationships are more evident in women than in men, suggesting the variations may be attributed to factors such as obesity and physical activity.
Acute FEV1 and FVC responses to bronchodilators decreased progressively over 4 years in patients with moderate to severe COPD, potentially impacting on the clinical responses to bronchodilator therapy.
Bardelli and Siravegna on the liquid biopsies: how DNA circulating in the blood is used as a diagnostic tool in cancer
Nick Navin reviews new techniques and strategies to study cancer at the single cell level
An analysis of DNA methylation changes during AML's treatment with DNMT inhibitors identifies genes specifically targeted by the drugs
A new approach using deep sequencing of X chromosome allows the study of cancer progression in colorectal cancer
Johann de Bono and colleagues on the frontiers of cancer monitoring with ciculating tumor cells
Patients with a do-not-resuscitate (DNR)-Comfort-Care order receive fewer aggressive treatment interventions after initiating the DNR order, suggesting that clear indication of medical care requirements for DNR patients ensures appropriate treatment.
Parasitic Ophiocordyceps fungi, who turn their ant hosts into ‘zombies’, can infect and kill multiple ant species but only manipulate behaviour in their specific host species; this could be related to the metabolites they secrete.
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