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Articles

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  • Surveillance leads to rabies reduction

    Introduction of a national surveillance programme for rabies has led to a reduction in incidence of the disease with regulation of post-exposure prophylaxis quality together with improved management and vaccination of domesticated animals key for its success.

    BMC Infectious Diseases 2014, 14:212
  • Image attributed to: iStock

    Impact of obesity on healthcare

    Andrew Renehan and Iain Buchan comment on a recent large scale study showing that elevated body mass index is linked to increased hospital admission rates in England, and discuss the direct impact of obesity on the healthcare system.

    BMC Medicine 2014, 12:64
  • Image attributed to: Katia Del Rio-Tsonis - a chick eye at E4 (BrdU staining)

    Understanding retinal regeneration

    Following injury of the retinal pigmented epithelium (RPE), dedifferentiation and increased FGF2 expression initiate repair, but Del Rio-Tsonis and colleagues identify the importance of the transcription factor Lin28, which can direct the complete reprogramming of the RPE in this regeneration process in the chick eye.

    BMC Biology 2014, 12:28
  • Regulators of TRAIL in breast cancer

    Novel molecular regulators of the tumor necrosis factor-related apoptosis inducing ligand (TRAIL) pathway in breast cancer cells were identified, suggesting their role in combination with TRAIL as potential therapeutic targets for breast cancer.

    Breast Cancer Research 2014, 16:R41
  • Eye disorders in golden retrievers linked to novel mutation in TTC8

    The authors use whole genome scanning to identify an association between the gene TTC8 and inherited eye disorders in golden retrievers. A single mutation in TTC8 was found by DNA sequencing, and then confirmed by screening a larger number of dogs.

    Canine Genetics and Epidemiology 2014, 1:4
  • Genetics of eye disorders in the dog

    Cathryn Mellersh looks at the mutations that have been associated with inherited eye disorders in the dog. Similarities between eye structure and disease in humans and dogs point to an increased role for dogs in helping us to understand and treat eye disorders in both species.

    Canine Genetics and Epidemiology 2014, 1:3
  • Approaches to canine health surveillance

    Authors at the Royal Veterinary College and the University of Sydney review the history and development of health surveillance systems in canine medicine. These systems each have their own strengths and weaknesses when it comes to monitoring dog health.

    Canine Genetics and Epidemiology 2014, 1:2
  • Every dog has its day: a new journal for canine genetics and epidemiology

    We are delighted to announce the launch of Canine Genetics and Epidemiology, an open access journal published by BioMed Central with the support and backing of the UK Kennel Club.

    Canine Genetics and Epidemiology 2014, 1:1
  • Image attributed to: NASA, Wikimedia Commons

    African microbiome research

    Leading researchers present their recommendations for harnessing microbiome and probiotic research in Sub-Saharan Africa.

    Microbiome 2014, 2:12
  • Image attributed to: From Rico et al.

    Gene expression in patient-derived xenografts

    Transcriptomic analysis shows for the first time that patient-derived xenografts in mice are more closely related to primary tumors than cell lines are for pancreatic tumors.

    Genome Medicine 2014, 6:27
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