Methylome analysis of Wilms tumor identifies differentially methylated biomarker regions that can be detected in cell-free circulating DNA
Latin American healthcare is straining to cope with chronic diseases such as diabetes; Armando Arredondo highlights the need for more resources to be allocated to preventive medicine, and discusses ways in which this may be achieved in these settings.
An Editorial summing up our thematic series on 'Cilia assembly mechanisms'. The full article collection can be accessed at www.ciliajournal.com/series/ciliaassemblymechanisms.
Sequencing of VDJ rearrangements and analysis of somatic hypermutations reveals two distinct clonal evolution modes in diffuse large B-cell lymphoma
Woodrat populations that have evolutionary experience of ingesting creosote toxins display similar biotransformation strategies compared to naïve populations, revealing key genes that are upregulated in response to a toxic diet.
New evidence contributing to our understanding of the neuropeptides critical for itch responses, with a look at the tissues in which these peptides are expressed and their positions in the itch circuit.
There is no relationship between days of continuous cover by a single intensivist and patient outcomes in adult, general ICUs in England but intensivist participation in handover is associated with increased mortality.
In a preliminary trial, mesalazine is safe for use in acutely malnourished children with severe environmental enteric dysfunction, indicating that further studies should target host inflammatory responses to treat these children
Many lung cancer-associated lncRNAs and their role in tumorigenesis are revealed in a transcriptional analysis
Next-generation sequencing (NGS) provides a large amount of information about tumor genetics; in this forum article, breast cancer specialists debate whether NGS can guide clinical decision making, or whether it is not yet ready for routine use.
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