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  • A phenomic approach to improving drug therapy

    Discussing a novel integrated approach to personalized medicine that begins with phenomic data, is stratified by genomics, and is ultimately refined by metabolomic pathway data.

    Human Genomics 2014, 8:16
  • Image attributed to: Flickr: Boonyarit Cheunsuchon

    Social class associated with serum lipid levels

    Occupational social class and educational level are associated with serum lipid levels and the relationships are more evident in women than in men, suggesting the variations may be attributed to factors such as obesity and physical activity.

    BMC Public Health 2014, 14:782
  • Image attributed to: James Heilman CC BY-SA 3.0

    Bronchodilator efficacy decreases in COPD lungs

    Acute FEV1 and FVC responses to bronchodilators decreased progressively over 4 years in patients with moderate to severe COPD, potentially impacting on the clinical responses to bronchodilator therapy.

    Respiratory Research 2014, 15:102
  • Cell-free DNA

    Bardelli and Siravegna on the liquid biopsies: how DNA circulating in the blood is used as a diagnostic tool in cancer

    Genome Biology 2014, 15:449
  • Single cell genomics

    Nick Navin reviews new techniques and strategies to study cancer at the single cell level

    Genome Biology 2014, 15:452
  • AML-related methylation regulation

    An analysis of DNA methylation changes during AML's treatment with DNMT inhibitors identifies genes specifically targeted by the drugs

    Genome Biology 2014, 15:406
  • X chromosome sequencing

    A new approach using deep sequencing of X chromosome allows the study of cancer progression in colorectal cancer

    Genome Biology 2014, 15:437
  • Circulating tumor cells

    Johann de Bono and colleagues on the frontiers of cancer monitoring with ciculating tumor cells

    Genome Biology 2014, 15:448
  • Image attributed to: istock photo

    DNR orders guide treatment decisions

    Patients with a do-not-resuscitate (DNR)-Comfort-Care order receive fewer aggressive treatment interventions after initiating the DNR order, suggesting that clear indication of medical care requirements for DNR patients ensures appropriate treatment.

    BMC Medicine 2014, 12:146
  • Image attributed to: From de Bekker et al 2014

    Mind control in zombie ants

    Parasitic Ophiocordyceps fungi, who turn their ant hosts into ‘zombies’, can infect and kill multiple ant species but only manipulate behaviour in their specific host species; this could be related to the metabolites they secrete.

    BMC Evolutionary Biology 2014, 14:166
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