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Articles

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  • Image attributed to: istock folder (lung)

    Clinical score predicts COPD mortality

    A clinical score predicts short-term mortality risk in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) that attend the emergency department, suggesting the score could help guide clinical decision making.

    BMC Medicine 2014, 12:66
  • Image attributed to: istock

    Verbal autopsy can quantify SCD burden

    Verbal autopsy tools have strong agreement with hospital diagnoses in identifying sickle cell disease (SCD) as a cause of death in children, suggesting they will be useful to quantify the contribution of SCD to childhood mortality in Africa.

    BMC Medicine 2014, 12:65
  • TNF alpha inhibitor therapy can decrease erosion

    Axial spondyloarthritis patients receiving tumor necrosis factor (TNF) alpha inhibitor therapy experience greater fat metaplasia and less erosion in the sacroiliac joints in comparison to standard therapy.

    Arthritis Research & Therapy 2014, 16:R100
  • Surveillance leads to rabies reduction

    Introduction of a national surveillance programme for rabies has led to a reduction in incidence of the disease with regulation of post-exposure prophylaxis quality together with improved management and vaccination of domesticated animals key for its success.

    BMC Infectious Diseases 2014, 14:212
  • Image attributed to: iStock

    Impact of obesity on healthcare

    Andrew Renehan and Iain Buchan comment on a recent large scale study showing that elevated body mass index is linked to increased hospital admission rates in England, and discuss the direct impact of obesity on the healthcare system.

    BMC Medicine 2014, 12:64
  • Regulators of TRAIL in breast cancer

    Novel molecular regulators of the tumor necrosis factor-related apoptosis inducing ligand (TRAIL) pathway in breast cancer cells were identified, suggesting their role in combination with TRAIL as potential therapeutic targets for breast cancer.

    Breast Cancer Research 2014, 16:R41
  • Image attributed to: Katia Del Rio-Tsonis - a chick eye at E4 (BrdU staining)

    Understanding retinal regeneration

    Following injury of the retinal pigmented epithelium (RPE), dedifferentiation and increased FGF2 expression initiate repair, but Del Rio-Tsonis and colleagues identify the importance of the RNA binding factor Lin28, which can direct the complete reprogramming of the RPE in this regeneration process in the chick eye.

    BMC Biology 2014, 12:28
  • Every dog has its day: a new journal for canine genetics and epidemiology

    We are delighted to announce the launch of Canine Genetics and Epidemiology, an open access journal published by BioMed Central with the support and backing of the UK Kennel Club.

    Canine Genetics and Epidemiology 2014, 1:1
  • Image attributed to: NASA, Wikimedia Commons

    African microbiome research

    Leading researchers present their recommendations for harnessing microbiome and probiotic research in Sub-Saharan Africa.

    Microbiome 2014, 2:12
  • Image attributed to: From Rico et al.

    Gene expression in patient-derived xenografts

    Transcriptomic analysis shows for the first time that patient-derived xenografts in mice are more closely related to primary tumors than cell lines are for pancreatic tumors.

    Genome Medicine 2014, 6:27
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