Human parechovirus, Aichi virus and salivirus were found in fecal samples from children in Hong Kong with gastroenteritis, providing the first information on the epidemiology of these emerging viruses in this region.
Patients over 65 years with visual impairment are more likely to have physical and mental comorbidities in comparison to their peers without visual impairment, indicating the need for specialized care to address individual needs in this patient group.
Evidence suggests that gene-environment interactions could modify breast cancer risk; Olivia Fletcher and Frank Dudbridge discuss progress in elucidating these interactions, highlighting that further validation in large cohort studies is required.
The authors investigated bovine viral diarrhoea virus (BVDV) transmission risk by combining statistical analysis of real serological data from surveyed beef and dairy herds with simulated data from a dynamic model.
Antigenic diversity of apical membrane antigen 1 (AMA1) in Plasmodium falciparum malaria is restricted to three alleles, suggesting that a multi-allele vaccine targeting limited AMA1 variants should confer protection against malaria.
In severely obese people, weight loss required for improvements in health-related quality of life (HRQL) is greater than conventional thresholds, and surgical treatment results in better HRQL, providing insights into effective weight loss strategies.
An R package that integrates functional annotation and biological knowledge to prioritize candidate functional variants, particularly in non-coding regions.
A computational approach to investigate 1.2 million somatic mutations in 36 cancer types using 3D protein structure information to identify putative cancer drivers and drug response biomarkers.
William Petri et al. comment on a recent trial showing that an anti-inflammatory drug is safe to treat environmental enteropathy (EE) in malnourished children, and indicate that although preliminary, this approach holds promise for the treatment of EE.
The house fly genome shows that it is genetically adapted to high pathogen loads and living in association with animal waste
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