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  • Image attributed to: wikimedia commons-Jason Rogers

    Monitoring influenza: use left or right nostril?

    Nasal swabs collected from left and right nostrils for influenza viral load monitoring displayed considerable sampling variability, highlighting the need for standardized sampling procedures.

    Virology Journal 2014, 11:2
  • Image attributed to: Wikipedia

    Ageing CD4 T cells

    Vineeta Bal and colleagues detect signs of ageing in mouse CD4 T cells as they patrol the body in readiness to participate in antigen-specific immune responses.  Older  cells have lower CD4 levels and a hyporesponsive phenotype associated with increased activation of the DUSP phosphatase and reactive oxygen species, suggesting  the possible use of small molecule inhibitors and anti-oxidants to increase vaccination efficiency in the elderly.

    BMC Biology 2014, 12:106
  • Image attributed to: Figure 7

    MudS mediates binucleation

    MudS, a microtubule binding protein isoform, appears to be a key regulator in production of binucleate cells, by triggering cells to go through mitosis without cytokinesis, during development of the Drosophila male accessory gland.

    BMC Developmental Biology 2014, 14:46
  • Image attributed to: Bruno in Columbus/wikipedia

    Dictyostelium density linked to predatory success

    Farmer and non-farmer clones of the social amoeba Dictyostelium discoideum do not differ in their ability to consume novel toxic strains of E. coli with increased numbers of bacteria or amoebae improving their respective likelihood of competitive victory over the other.

    BMC Microbiology 2014, 14:328
  • Minimizing “failure to rescue” in surgery

    August and colleagues examine the factors leading to their transhiatal esophagectomy program achieving low mortality rates. The findings show that focus on avoiding "failure to rescue" and a surgeon-driven commitment to quality improvement may lead to low mortality rates for this surgical procedure.

    Annals of Surgical Innovation and Research 2014, 8:9
  • Chromosomal aberrations in genetic disease

    Chromosomal aberrations underlie genetic disease in roughly 15% of patients with multiple congenital abnormalities and/or mental retardation. A new review discusses current methods for breakpoint identification and their impact on the interpretation of chromosome abmormalities.

    Molecular Cytogenetics 2014, 7:100
  • Image attributed to: Klaus D Peter CC-BY 2.0

    Percutaneous versus surgical tracheotomy

    In critically ill adult patients, percutaneous tracheotomy techniques can be performed faster than a surgical tracheostomy and also reduce stoma inflammation and infection.

    Critical Care 2014, 18:544
  • Image attributed to: istock

    Limited evidence for flu vaccine benefits

    In a systematic review, evidence for the protective effects of influenza vaccination in patients with end-stage renal disease is limited, highlighting the need for more studies to assess vaccine effectiveness in this at-risk population.

    BMC Medicine 2014, 12:244
  • Image attributed to: Flickr (CC, Ashish Jain)

    Tobacco use linked to social factors

    Population-based data from 30 sub-Saharan African countries provides country-level prevalence estimates of tobacco use, demonstrating varying use of smoking and smokeless tobacco that are linked to social determinants such as gender, age and education.

    BMC Medicine 2014, 12:243
  • Image attributed to: From wikimedia, by Nilfanion and Dr Greg, CC

    Cancer risk by ethnicity in England

    Analysis of cancer incidence data in England reveals that risk of breast and gynaecological cancers varies by ethnic group but groups typically grouped together are not homogenous with regards to their cancer risk.

    BMC Cancer 2014, 14:979
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