Prompt recognition and treatment of sepsis is essential to reduce mortality risk; in this forum article, clinicians and researchers working in sepsis care discuss the importance of early detection, and special considerations in different patient groups.
To inform the design of patient and public involvement (PPI) training, researchers and PPI contributors were interviewed; results indicate that training for researchers is beneficial, though informants were less inclined to support training for PPI contributors.
Human vertebrae with Schmorl’s nodes, indicative of disc herniation, share more similarities in shape with chimpanzee or orangutan vertebrae than do human vertebrae without Schmorl’s nodes, suggesting sufferers vertebrae are less well adapted to bipedalism.
Three new species of spiny-throated reed frog are described from specimens collected in the Eastern African Afromontane biodiversity hotspot; the limited ranges of the new species raises concerns about their conservation.
The genomes of two species of bumblebee, the European Bombus terrestris and the North American B. impatiens, are sequenced and compared
Evidence from the literature suggests that some risks associated with cigar smoking can be as high or higher than those associated with cigarette smoking, especially at the highest doses and levels of inhalation for cigar smoking.
Thrombocytopenia is associated with disease severity in patients with falciparum malaria, but is no better than established indices to predict patient prognosis, suggesting that thrombocytopenia has limited value in malaria triage and management.
Bumblebees, honeybees and a solitary bee have similar numbers of immune genes so immune gene complement is not linked to sociality
Adipose cells in the tumour microenvironment may be contributing to resistance to Trastuzumab, a targeted treatment for HER2+ breast cancer.
Higher levels of free thyroxine are associated with increased risk of age-related macular degeneration (AMD) and retinal pigment alterations, highlighting a potential role of thyroid hormone signaling in the development of AMD.
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