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  • Multi-drug resistance in sepsis

    Multi-drug resistance is associated with a three-fold increase in the risk of hospital mortality in sepsis due to Gram-negative bacteremia

    Critical Care 2014, 18:596
  • Image attributed to: From Berman and colleagues

    YMAP: yeast mapping analysis pipeline

    A tool for genome-wide visualization and analysis of mutations in Candida albicans, allowing interrogation of copy number variation,SNPs and loss of heterozygosity.

    Genome Medicine 2014, 6:100
  • Image attributed to: From Fig 7 Inouye et al.

    SRST2 for genomic surveillance

    A read-mapping based tool for fast and accurate detection of genes, alleles and multi-locus sequence types from whole genome sequences for common bacterial pathogens.

    Genome Medicine 2014, 6:90
  • A window into the genome

    Tsompana and Buck provide an up-to-date analysis of chromatin accessibility assays, giving a perspective on future improvements necessary for moving the field of chromatin profiling forward.

    Epigenetics & Chromatin 2014, 7:33
  • Image attributed to: A. baumnanni from CDC. credit Janice Carr via wikimedia commons

    Outbreak control guided by genome sequencing

    Whole genome sequencing of multi-drug resistant Acinetobacter baumannii in a prolonged hospital outbreak in Birmingham, UK, advises on control and prevention strategies.

    Genome Medicine 2014, 6:70
  • Image attributed to: legs and joints

    Osteoarthritis patients susceptible to alphaviral infection

    Osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection, indicating osteoarthritis as a risk factor for alphavirus-induced bone pathology.

    Virology Journal 2014, 11:189
  • Image attributed to: Wikipedia, Creative Commons 2.0

    Promiscuity pays

    Monogamous female Drosophila suffer decreased fertility compared to multiply mated females, apparently due to differing transcriptional changes in response to mating; monogamous females have a more virgin-like expression profile than promiscuous females.

    BMC Evolutionary Biology 2014, 14:239
  • Image attributed to: mallard-wikimedia commons-Justin DiPierro

    Discovery of a new Avian Bornavirus genotype

    A previously undescribed genotype of avian bornavirus was isolated from wild ducks in central Oklahoma, enhancing our knowledge on the genetic diversity and epidemiology of this virus.

    Virology Journal 2014, 11:197
  • A methylation array of ethical concerns

    Methylation array data can identify individuals and convey protected health information, yet federal policy dictates that data from these arrays are deposited in publicly available databases.

    Clinical Epigenetics 2014, 6:28
  • Image attributed to: Travis Isaacs

    IGF-1 therapy effective for sudden deafness

    In a randomized clinical trial, sudden deafness refractory to systemic corticosteroid therapy is responsive to topical application of insulin-like growth factor-1 (IGF-1), providing an alternative for patients resistant to systemic glucocorticoids.

    BMC Medicine 2014, 12:219
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