Table 1

Symbolic notations used and corresponding units
Insulin aggregation kinetics measured by absorbance or fluorescence
X : Amyloid aggregation growth measured as absorbance at 600 nm, relative ThT fluorescence intensity (%) and ThT fluorescence intensity at 482 nm or 490 nm. Units: absorbance units (AU) or (%).
t : Time. Units: h or d
Xm : Maximum aggregation growth. Units: AU or %
vm : Maximum aggregation rate. Units: AU h−1, AU d−1 or % h−1
λ : Lag phase. Units: h or d
Xm : Maximum insulin aggregation affected by chemical agent. Units: AU or %
vm : Maximum insulin aggregation rate affected by chemical agent. Units: AU h−1, AU d−1 or % h−1
λ• : Lag phase affected by chemical agent. Units: h or d
Concentration effects on insulin aggregation kinetics
C : Concentration of chemical agent. Units: mM or μM
Kx : Maximum response affecting on Xm. Dimensionless
mx : Concentration corresponding to the semi-maximum response affecting on Xm. Units: mM or μM
ax : Shape parameter affecting on Xm. Dimensionless
Kv : Maximum response affecting on vm. Dimensionless
mv : Concentration corresponding to the semi-maximum response affecting on vm. Units: mM or μM
av : Shape parameter affecting on vm. Dimensionless
Kλ : Maximum response affecting on λ. Dimensionless
mλ : Concentration corresponding to the semi-maximum response affecting on λ. Units: mM or μM
aλ : Shape parameter affecting on λ. Dimensionless

Vázquez

Vázquez BMC Pharmacology and Toxicology 2014 15:9   doi:10.1186/2050-6511-15-9

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