Exposure to UVC reduced ctb-1 and nd-5 expression at early timepoints, but resulted in higher levels of all mRNAs at later times (wild-type N2 strain).ctb-1 and nd-5 are mtDNA-encoded, and C34B2.8, D2030.4, K09A9.5, polg-1 are nDNA-encoded, mitochondrial proteins. polg-1 is graphed separately to avoid obscuring the smaller fold-changes observed in the other genes; note different y-axes. p < 0.0001 for all main and interactive effects, 3 factor ANOVA. Fold change is relative to the mRNA of the same gene at the same time without UVC exposure. n = 3–6.
Leung et al. BMC Pharmacology and Toxicology 2013 14:9 doi:10.1186/2050-6511-14-9