Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family
1 Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, USA
2 Biochemical Technologies, Science and Technology Division, Corning Inc., Corning, NY, USA
BMC Pharmacology and Toxicology 2013, 14:17 doi:10.1186/2050-6511-14-17Published: 12 March 2013
Additional file 1: Figure S1:
DMR characteristics of a subset of ligands in parental HEK293 cells, Figure S2: A colored heat map based on the DMR of opioid ligands in five different cell lines, Figure S3: A colored heat map based on the selectivity of opioid ligands to block the DMR of control agonists in respective cell lines, Table S1: Opioid ligands and their affinity binding to the MOR, Table S2: Opioid ligands and their affinity binding to the DOR, and Table S3: Opioid ligands and their affinity binding to the KOR.
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